| Full name: X-ray radiation resistance associated 1 | Alias Symbol: FLJ00225 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 143570 | HGNC ID: HGNC:18868 | Ensembl Gene: ENSG00000166435 | OMIM ID: 609788 |
| Drug and gene relationship at DGIdb | |||
Expression of XRRA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XRRA1 | 143570 | 230557_at | 0.5081 | 0.4848 | |
| GSE26886 | XRRA1 | 143570 | 230557_at | 0.0235 | 0.8881 | |
| GSE45670 | XRRA1 | 143570 | 230557_at | 0.1420 | 0.1004 | |
| GSE53622 | XRRA1 | 143570 | 16835 | 0.3728 | 0.0213 | |
| GSE53624 | XRRA1 | 143570 | 16835 | 0.5081 | 0.0000 | |
| GSE63941 | XRRA1 | 143570 | 237666_at | 0.4279 | 0.0638 | |
| GSE77861 | XRRA1 | 143570 | 230557_at | -0.1274 | 0.4816 | |
| GSE97050 | XRRA1 | 143570 | A_23_P370162 | -0.4833 | 0.2018 | |
| SRP007169 | XRRA1 | 143570 | RNAseq | 0.3021 | 0.4624 | |
| SRP008496 | XRRA1 | 143570 | RNAseq | 0.9209 | 0.0090 | |
| SRP064894 | XRRA1 | 143570 | RNAseq | 0.0913 | 0.8012 | |
| SRP133303 | XRRA1 | 143570 | RNAseq | -0.5257 | 0.0021 | |
| SRP159526 | XRRA1 | 143570 | RNAseq | 0.0608 | 0.9126 | |
| SRP193095 | XRRA1 | 143570 | RNAseq | -0.3781 | 0.0442 | |
| SRP219564 | XRRA1 | 143570 | RNAseq | 1.1376 | 0.0460 | |
| TCGA | XRRA1 | 143570 | RNAseq | -0.1073 | 0.1919 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by XRRA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XRRA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XRRA1 | 143570 | 7 | 8 | 15 | |
| GSE20123 | XRRA1 | 143570 | 7 | 7 | 16 | |
| GSE43470 | XRRA1 | 143570 | 5 | 4 | 34 | |
| GSE46452 | XRRA1 | 143570 | 7 | 22 | 30 | |
| GSE47630 | XRRA1 | 143570 | 6 | 14 | 20 | |
| GSE54993 | XRRA1 | 143570 | 8 | 3 | 59 | |
| GSE54994 | XRRA1 | 143570 | 8 | 15 | 30 | |
| GSE60625 | XRRA1 | 143570 | 4 | 3 | 4 | |
| GSE74703 | XRRA1 | 143570 | 4 | 3 | 29 | |
| GSE74704 | XRRA1 | 143570 | 5 | 3 | 12 | |
| TCGA | XRRA1 | 143570 | 22 | 33 | 41 |
Total number of gains: 83; Total number of losses: 115; Total Number of normals: 290.
Somatic mutations of XRRA1:
Generating mutation plots.
Highly correlated genes for XRRA1:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XRRA1 | C19orf47 | 0.836682 | 3 | 0 | 3 |
| XRRA1 | CRYBB2 | 0.803306 | 3 | 0 | 3 |
| XRRA1 | CADM3 | 0.782865 | 3 | 0 | 3 |
| XRRA1 | TIGD1 | 0.776271 | 3 | 0 | 3 |
| XRRA1 | PPP2R3A | 0.770647 | 3 | 0 | 3 |
| XRRA1 | RAB3GAP2 | 0.769545 | 3 | 0 | 3 |
| XRRA1 | DRAP1 | 0.76814 | 3 | 0 | 3 |
| XRRA1 | VAMP2 | 0.76464 | 3 | 0 | 3 |
| XRRA1 | ZNF683 | 0.764083 | 3 | 0 | 3 |
| XRRA1 | MAPRE3 | 0.746035 | 3 | 0 | 3 |
| XRRA1 | WDR82 | 0.744954 | 3 | 0 | 3 |
| XRRA1 | CCDC159 | 0.741272 | 3 | 0 | 3 |
| XRRA1 | MED9 | 0.730678 | 3 | 0 | 3 |
| XRRA1 | ENTPD2 | 0.729648 | 3 | 0 | 3 |
| XRRA1 | FAM53B | 0.728481 | 3 | 0 | 3 |
| XRRA1 | RILP | 0.719206 | 3 | 0 | 3 |
| XRRA1 | A4GALT | 0.718026 | 3 | 0 | 3 |
| XRRA1 | ZNF787 | 0.716131 | 3 | 0 | 3 |
| XRRA1 | NR1H2 | 0.716025 | 3 | 0 | 3 |
| XRRA1 | IL3RA | 0.711128 | 3 | 0 | 3 |
For details and further investigation, click here
