| Full name: cytochrome b561 | Alias Symbol: FRRS2|CYB561A1 | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 1534 | HGNC ID: HGNC:2571 | Ensembl Gene: ENSG00000008283 | OMIM ID: 600019 |
| Drug and gene relationship at DGIdb | |||
Expression of CYB561:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYB561 | 1534 | 217200_x_at | -0.0256 | 0.9537 | |
| GSE20347 | CYB561 | 1534 | 217200_x_at | -0.2363 | 0.0184 | |
| GSE23400 | CYB561 | 1534 | 217200_x_at | -0.1156 | 0.0056 | |
| GSE26886 | CYB561 | 1534 | 217200_x_at | -0.7085 | 0.0001 | |
| GSE29001 | CYB561 | 1534 | 217200_x_at | -0.1692 | 0.2036 | |
| GSE38129 | CYB561 | 1534 | 217200_x_at | -0.0758 | 0.5777 | |
| GSE45670 | CYB561 | 1534 | 217200_x_at | -0.0086 | 0.9445 | |
| GSE53622 | CYB561 | 1534 | 65712 | -0.0310 | 0.7971 | |
| GSE53624 | CYB561 | 1534 | 65712 | -0.2810 | 0.0000 | |
| GSE63941 | CYB561 | 1534 | 207986_x_at | 0.0017 | 0.9951 | |
| GSE77861 | CYB561 | 1534 | 209163_at | -0.2874 | 0.2041 | |
| GSE97050 | CYB561 | 1534 | A_23_P218331 | 0.2408 | 0.5785 | |
| SRP007169 | CYB561 | 1534 | RNAseq | -1.5789 | 0.0000 | |
| SRP008496 | CYB561 | 1534 | RNAseq | -1.2098 | 0.0000 | |
| SRP064894 | CYB561 | 1534 | RNAseq | -0.5180 | 0.0240 | |
| SRP133303 | CYB561 | 1534 | RNAseq | -0.3430 | 0.1382 | |
| SRP159526 | CYB561 | 1534 | RNAseq | -0.3697 | 0.1623 | |
| SRP193095 | CYB561 | 1534 | RNAseq | -0.5642 | 0.0000 | |
| SRP219564 | CYB561 | 1534 | RNAseq | 0.0482 | 0.9247 | |
| TCGA | CYB561 | 1534 | RNAseq | -0.1238 | 0.0148 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CYB561 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYB561:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYB561 | 1534 | 4 | 1 | 25 | |
| GSE20123 | CYB561 | 1534 | 4 | 1 | 25 | |
| GSE43470 | CYB561 | 1534 | 4 | 0 | 39 | |
| GSE46452 | CYB561 | 1534 | 31 | 0 | 28 | |
| GSE47630 | CYB561 | 1534 | 7 | 1 | 32 | |
| GSE54993 | CYB561 | 1534 | 2 | 5 | 63 | |
| GSE54994 | CYB561 | 1534 | 9 | 5 | 39 | |
| GSE60625 | CYB561 | 1534 | 4 | 0 | 7 | |
| GSE74703 | CYB561 | 1534 | 4 | 0 | 32 | |
| GSE74704 | CYB561 | 1534 | 3 | 1 | 16 | |
| TCGA | CYB561 | 1534 | 30 | 8 | 58 |
Total number of gains: 102; Total number of losses: 22; Total Number of normals: 364.
Somatic mutations of CYB561:
Generating mutation plots.
Highly correlated genes for CYB561:
Showing top 20/669 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYB561 | PLEKHG1 | 0.796104 | 3 | 0 | 3 |
| CYB561 | MARVELD2 | 0.771711 | 3 | 0 | 3 |
| CYB561 | PPM1K | 0.761242 | 3 | 0 | 3 |
| CYB561 | PHYHD1 | 0.743798 | 3 | 0 | 3 |
| CYB561 | MAP7 | 0.737269 | 4 | 0 | 4 |
| CYB561 | BAIAP2L1 | 0.734253 | 3 | 0 | 3 |
| CYB561 | ELAC1 | 0.732588 | 3 | 0 | 3 |
| CYB561 | SLFNL1 | 0.732035 | 3 | 0 | 3 |
| CYB561 | C3orf38 | 0.708968 | 3 | 0 | 3 |
| CYB561 | ZNF555 | 0.705663 | 3 | 0 | 3 |
| CYB561 | TMEM120A | 0.704843 | 5 | 0 | 4 |
| CYB561 | WDR26 | 0.703839 | 5 | 0 | 4 |
| CYB561 | CRYBG3 | 0.700235 | 3 | 0 | 3 |
| CYB561 | HECW2 | 0.699741 | 4 | 0 | 4 |
| CYB561 | DCAF12 | 0.699488 | 4 | 0 | 4 |
| CYB561 | RINT1 | 0.694862 | 5 | 0 | 5 |
| CYB561 | APRT | 0.691797 | 4 | 0 | 4 |
| CYB561 | BTAF1 | 0.686344 | 3 | 0 | 3 |
| CYB561 | SIAH2 | 0.682361 | 3 | 0 | 3 |
| CYB561 | SLC39A11 | 0.681888 | 4 | 0 | 4 |
For details and further investigation, click here
