| Full name: DDB1 and CUL4 associated factor 12 | Alias Symbol: DKFZP434O125|MGC1058|CT102|TCC52 | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 25853 | HGNC ID: HGNC:19911 | Ensembl Gene: ENSG00000198876 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DCAF12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCAF12 | 25853 | 224789_at | -0.0476 | 0.9576 | |
| GSE26886 | DCAF12 | 25853 | 224789_at | -0.6865 | 0.0001 | |
| GSE45670 | DCAF12 | 25853 | 224789_at | -0.0405 | 0.8552 | |
| GSE53622 | DCAF12 | 25853 | 27573 | -0.2381 | 0.0081 | |
| GSE53624 | DCAF12 | 25853 | 27573 | -0.3880 | 0.0000 | |
| GSE63941 | DCAF12 | 25853 | 224789_at | 0.5887 | 0.1456 | |
| GSE77861 | DCAF12 | 25853 | 224789_at | -0.5599 | 0.0657 | |
| GSE97050 | DCAF12 | 25853 | A_23_P255257 | -0.0392 | 0.9216 | |
| SRP007169 | DCAF12 | 25853 | RNAseq | -1.7160 | 0.0000 | |
| SRP008496 | DCAF12 | 25853 | RNAseq | -1.3287 | 0.0000 | |
| SRP064894 | DCAF12 | 25853 | RNAseq | -0.8656 | 0.0000 | |
| SRP133303 | DCAF12 | 25853 | RNAseq | -0.4727 | 0.0002 | |
| SRP159526 | DCAF12 | 25853 | RNAseq | -0.8500 | 0.0007 | |
| SRP193095 | DCAF12 | 25853 | RNAseq | -0.8498 | 0.0000 | |
| SRP219564 | DCAF12 | 25853 | RNAseq | -0.5941 | 0.2464 | |
| TCGA | DCAF12 | 25853 | RNAseq | 0.1115 | 0.0474 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by DCAF12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCAF12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCAF12 | 25853 | 3 | 15 | 12 | |
| GSE20123 | DCAF12 | 25853 | 3 | 15 | 12 | |
| GSE43470 | DCAF12 | 25853 | 3 | 10 | 30 | |
| GSE46452 | DCAF12 | 25853 | 6 | 15 | 38 | |
| GSE47630 | DCAF12 | 25853 | 1 | 20 | 19 | |
| GSE54993 | DCAF12 | 25853 | 6 | 0 | 64 | |
| GSE54994 | DCAF12 | 25853 | 6 | 13 | 34 | |
| GSE60625 | DCAF12 | 25853 | 0 | 0 | 11 | |
| GSE74703 | DCAF12 | 25853 | 2 | 7 | 27 | |
| GSE74704 | DCAF12 | 25853 | 0 | 12 | 8 | |
| TCGA | DCAF12 | 25853 | 17 | 44 | 35 |
Total number of gains: 47; Total number of losses: 151; Total Number of normals: 290.
Somatic mutations of DCAF12:
Generating mutation plots.
Highly correlated genes for DCAF12:
Showing top 20/878 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCAF12 | CLEC16A | 0.776192 | 3 | 0 | 3 |
| DCAF12 | CANT1 | 0.765564 | 4 | 0 | 4 |
| DCAF12 | UBAP1 | 0.74989 | 7 | 0 | 7 |
| DCAF12 | WDR77 | 0.747988 | 3 | 0 | 3 |
| DCAF12 | HMGA1 | 0.743598 | 3 | 0 | 3 |
| DCAF12 | ACAA1 | 0.737546 | 4 | 0 | 4 |
| DCAF12 | OS9 | 0.724356 | 3 | 0 | 3 |
| DCAF12 | DNAJA2 | 0.722845 | 3 | 0 | 3 |
| DCAF12 | ORMDL2 | 0.718742 | 4 | 0 | 4 |
| DCAF12 | NPAS2 | 0.710024 | 3 | 0 | 3 |
| DCAF12 | CPA4 | 0.708031 | 4 | 0 | 4 |
| DCAF12 | CNOT11 | 0.703832 | 3 | 0 | 3 |
| DCAF12 | CDC37L1 | 0.702435 | 4 | 0 | 3 |
| DCAF12 | CYB561 | 0.699488 | 4 | 0 | 4 |
| DCAF12 | TSPAN6 | 0.69903 | 7 | 0 | 7 |
| DCAF12 | FOPNL | 0.698889 | 3 | 0 | 3 |
| DCAF12 | PINK1 | 0.698617 | 3 | 0 | 3 |
| DCAF12 | CASP3 | 0.698171 | 5 | 0 | 4 |
| DCAF12 | AP1B1 | 0.694592 | 4 | 0 | 3 |
| DCAF12 | PLK3 | 0.694266 | 3 | 0 | 3 |
For details and further investigation, click here
