| Full name: elaC ribonuclease Z 1 | Alias Symbol: D29 | ||
| Type: protein-coding gene | Cytoband: 18q21.2 | ||
| Entrez ID: 55520 | HGNC ID: HGNC:14197 | Ensembl Gene: ENSG00000141642 | OMIM ID: 608079 |
| Drug and gene relationship at DGIdb | |||
Expression of ELAC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELAC1 | 55520 | 222869_s_at | -0.0994 | 0.8836 | |
| GSE20347 | ELAC1 | 55520 | 219325_s_at | -0.1708 | 0.0480 | |
| GSE23400 | ELAC1 | 55520 | 219325_s_at | -0.0893 | 0.0000 | |
| GSE26886 | ELAC1 | 55520 | 222869_s_at | -0.4892 | 0.0234 | |
| GSE29001 | ELAC1 | 55520 | 219325_s_at | -0.1974 | 0.2520 | |
| GSE38129 | ELAC1 | 55520 | 219325_s_at | -0.1471 | 0.0367 | |
| GSE45670 | ELAC1 | 55520 | 222869_s_at | -0.0586 | 0.7612 | |
| GSE53622 | ELAC1 | 55520 | 81209 | -0.3644 | 0.0011 | |
| GSE53624 | ELAC1 | 55520 | 81209 | -0.0623 | 0.5952 | |
| GSE63941 | ELAC1 | 55520 | 222869_s_at | -1.2562 | 0.0300 | |
| GSE77861 | ELAC1 | 55520 | 222869_s_at | -0.0682 | 0.6290 | |
| GSE97050 | ELAC1 | 55520 | A_23_P15944 | 0.0868 | 0.6765 | |
| SRP007169 | ELAC1 | 55520 | RNAseq | -0.9061 | 0.0540 | |
| SRP008496 | ELAC1 | 55520 | RNAseq | 0.1500 | 0.7588 | |
| SRP064894 | ELAC1 | 55520 | RNAseq | 0.0493 | 0.7843 | |
| SRP133303 | ELAC1 | 55520 | RNAseq | -0.3635 | 0.0559 | |
| SRP159526 | ELAC1 | 55520 | RNAseq | 0.1246 | 0.7680 | |
| SRP193095 | ELAC1 | 55520 | RNAseq | -0.1900 | 0.1526 | |
| SRP219564 | ELAC1 | 55520 | RNAseq | 0.0583 | 0.8773 | |
| TCGA | ELAC1 | 55520 | RNAseq | -0.2473 | 0.0022 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ELAC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELAC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELAC1 | 55520 | 1 | 9 | 20 | |
| GSE20123 | ELAC1 | 55520 | 1 | 9 | 20 | |
| GSE43470 | ELAC1 | 55520 | 0 | 4 | 39 | |
| GSE46452 | ELAC1 | 55520 | 1 | 26 | 32 | |
| GSE47630 | ELAC1 | 55520 | 5 | 20 | 15 | |
| GSE54993 | ELAC1 | 55520 | 9 | 0 | 61 | |
| GSE54994 | ELAC1 | 55520 | 1 | 17 | 35 | |
| GSE60625 | ELAC1 | 55520 | 0 | 4 | 7 | |
| GSE74703 | ELAC1 | 55520 | 0 | 4 | 32 | |
| GSE74704 | ELAC1 | 55520 | 1 | 6 | 13 | |
| TCGA | ELAC1 | 55520 | 8 | 45 | 43 |
Total number of gains: 27; Total number of losses: 144; Total Number of normals: 317.
Somatic mutations of ELAC1:
Generating mutation plots.
Highly correlated genes for ELAC1:
Showing top 20/583 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELAC1 | ZNF41 | 0.795709 | 3 | 0 | 3 |
| ELAC1 | ZW10 | 0.771501 | 3 | 0 | 3 |
| ELAC1 | LMBRD2 | 0.757292 | 3 | 0 | 3 |
| ELAC1 | ITPRIPL2 | 0.742314 | 3 | 0 | 3 |
| ELAC1 | CYB561 | 0.732588 | 3 | 0 | 3 |
| ELAC1 | DOCK10 | 0.726557 | 3 | 0 | 3 |
| ELAC1 | DNAJC3 | 0.725947 | 3 | 0 | 3 |
| ELAC1 | NAA35 | 0.719482 | 3 | 0 | 3 |
| ELAC1 | MCPH1 | 0.719369 | 3 | 0 | 3 |
| ELAC1 | CENPV | 0.716916 | 3 | 0 | 3 |
| ELAC1 | MTMR12 | 0.713259 | 4 | 0 | 4 |
| ELAC1 | UGP2 | 0.712868 | 3 | 0 | 3 |
| ELAC1 | NUB1 | 0.70914 | 5 | 0 | 4 |
| ELAC1 | LSM14A | 0.705743 | 3 | 0 | 3 |
| ELAC1 | ZNF564 | 0.704519 | 6 | 0 | 6 |
| ELAC1 | KIAA2026 | 0.704064 | 3 | 0 | 3 |
| ELAC1 | ATG4C | 0.703524 | 4 | 0 | 4 |
| ELAC1 | PACRGL | 0.703498 | 3 | 0 | 3 |
| ELAC1 | AP3M1 | 0.700804 | 3 | 0 | 3 |
| ELAC1 | ZNF784 | 0.700664 | 3 | 0 | 3 |
For details and further investigation, click here
