| Full name: phytanoyl-CoA dioxygenase domain containing 1 | Alias Symbol: MGC16638 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 254295 | HGNC ID: HGNC:23396 | Ensembl Gene: ENSG00000175287 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PHYHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHYHD1 | 254295 | 226846_at | -1.6556 | 0.0054 | |
| GSE26886 | PHYHD1 | 254295 | 226846_at | -1.2236 | 0.0000 | |
| GSE45670 | PHYHD1 | 254295 | 226846_at | -0.9136 | 0.0003 | |
| GSE53622 | PHYHD1 | 254295 | 53966 | -2.2140 | 0.0000 | |
| GSE53624 | PHYHD1 | 254295 | 26992 | -2.4927 | 0.0000 | |
| GSE63941 | PHYHD1 | 254295 | 226846_at | -0.8506 | 0.4136 | |
| GSE77861 | PHYHD1 | 254295 | 226846_at | -0.4979 | 0.0020 | |
| GSE97050 | PHYHD1 | 254295 | A_23_P307844 | -0.1656 | 0.7639 | |
| SRP007169 | PHYHD1 | 254295 | RNAseq | -0.3691 | 0.6760 | |
| SRP008496 | PHYHD1 | 254295 | RNAseq | -1.0424 | 0.1769 | |
| SRP064894 | PHYHD1 | 254295 | RNAseq | -1.0281 | 0.0125 | |
| SRP133303 | PHYHD1 | 254295 | RNAseq | -2.4735 | 0.0000 | |
| SRP159526 | PHYHD1 | 254295 | RNAseq | -2.6947 | 0.0000 | |
| SRP193095 | PHYHD1 | 254295 | RNAseq | -1.9783 | 0.0000 | |
| SRP219564 | PHYHD1 | 254295 | RNAseq | -1.3945 | 0.0029 | |
| TCGA | PHYHD1 | 254295 | RNAseq | -1.2251 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by PHYHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHYHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHYHD1 | 254295 | 6 | 9 | 15 | |
| GSE20123 | PHYHD1 | 254295 | 6 | 9 | 15 | |
| GSE43470 | PHYHD1 | 254295 | 5 | 8 | 30 | |
| GSE46452 | PHYHD1 | 254295 | 6 | 13 | 40 | |
| GSE47630 | PHYHD1 | 254295 | 3 | 16 | 21 | |
| GSE54993 | PHYHD1 | 254295 | 3 | 3 | 64 | |
| GSE54994 | PHYHD1 | 254295 | 11 | 8 | 34 | |
| GSE60625 | PHYHD1 | 254295 | 0 | 0 | 11 | |
| GSE74703 | PHYHD1 | 254295 | 5 | 6 | 25 | |
| GSE74704 | PHYHD1 | 254295 | 3 | 7 | 10 | |
| TCGA | PHYHD1 | 254295 | 27 | 24 | 45 |
Total number of gains: 75; Total number of losses: 103; Total Number of normals: 310.
Somatic mutations of PHYHD1:
Generating mutation plots.
Highly correlated genes for PHYHD1:
Showing top 20/1684 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHYHD1 | SFTA2 | 0.766369 | 4 | 0 | 4 |
| PHYHD1 | PDLIM2 | 0.762175 | 5 | 0 | 5 |
| PHYHD1 | MKRN2 | 0.761878 | 4 | 0 | 4 |
| PHYHD1 | CNPPD1 | 0.759879 | 6 | 0 | 6 |
| PHYHD1 | ACOX2 | 0.758878 | 6 | 0 | 6 |
| PHYHD1 | EVC2 | 0.75869 | 3 | 0 | 3 |
| PHYHD1 | GPD1L | 0.758542 | 7 | 0 | 7 |
| PHYHD1 | MGST2 | 0.75556 | 7 | 0 | 7 |
| PHYHD1 | MED7 | 0.75513 | 3 | 0 | 3 |
| PHYHD1 | ANKRD35 | 0.75311 | 6 | 0 | 6 |
| PHYHD1 | SNCG | 0.751711 | 3 | 0 | 3 |
| PHYHD1 | CLDND1 | 0.749634 | 3 | 0 | 3 |
| PHYHD1 | USP54 | 0.749303 | 7 | 0 | 7 |
| PHYHD1 | SLC25A27 | 0.746616 | 3 | 0 | 3 |
| PHYHD1 | DLG2 | 0.746589 | 7 | 0 | 6 |
| PHYHD1 | DDAH1 | 0.744374 | 7 | 0 | 7 |
| PHYHD1 | CYB561 | 0.743798 | 3 | 0 | 3 |
| PHYHD1 | PLLP | 0.739776 | 7 | 0 | 7 |
| PHYHD1 | SLC22A15 | 0.738356 | 3 | 0 | 3 |
| PHYHD1 | RMND5B | 0.73759 | 7 | 0 | 7 |
For details and further investigation, click here
