| Full name: B-TFIID TATA-box binding protein associated factor 1 | Alias Symbol: TAFII170|TAF172|MOT1|TAF-172|TAF(II)170 | ||
| Type: protein-coding gene | Cytoband: 10q23.32 | ||
| Entrez ID: 9044 | HGNC ID: HGNC:17307 | Ensembl Gene: ENSG00000095564 | OMIM ID: 605191 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BTAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTAF1 | 9044 | 209430_at | -0.2227 | 0.6076 | |
| GSE20347 | BTAF1 | 9044 | 209430_at | -0.3703 | 0.0123 | |
| GSE23400 | BTAF1 | 9044 | 209430_at | -0.0793 | 0.4168 | |
| GSE26886 | BTAF1 | 9044 | 209430_at | -0.6427 | 0.0429 | |
| GSE29001 | BTAF1 | 9044 | 209430_at | -0.4674 | 0.0152 | |
| GSE38129 | BTAF1 | 9044 | 209430_at | -0.1930 | 0.1663 | |
| GSE45670 | BTAF1 | 9044 | 209430_at | -0.3822 | 0.0017 | |
| GSE53622 | BTAF1 | 9044 | 2277 | 0.1914 | 0.0055 | |
| GSE53624 | BTAF1 | 9044 | 2277 | -0.0828 | 0.2274 | |
| GSE63941 | BTAF1 | 9044 | 209430_at | -0.3171 | 0.4777 | |
| GSE77861 | BTAF1 | 9044 | 209430_at | -0.2465 | 0.3746 | |
| GSE97050 | BTAF1 | 9044 | A_23_P408675 | 0.2368 | 0.2908 | |
| SRP007169 | BTAF1 | 9044 | RNAseq | -0.1095 | 0.7727 | |
| SRP008496 | BTAF1 | 9044 | RNAseq | 0.0160 | 0.9343 | |
| SRP064894 | BTAF1 | 9044 | RNAseq | -0.5856 | 0.0858 | |
| SRP133303 | BTAF1 | 9044 | RNAseq | -0.1180 | 0.2375 | |
| SRP159526 | BTAF1 | 9044 | RNAseq | -0.7637 | 0.0287 | |
| SRP193095 | BTAF1 | 9044 | RNAseq | -0.2102 | 0.0101 | |
| SRP219564 | BTAF1 | 9044 | RNAseq | -0.8441 | 0.0441 | |
| TCGA | BTAF1 | 9044 | RNAseq | -0.1117 | 0.0169 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BTAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTAF1 | 9044 | 2 | 7 | 21 | |
| GSE20123 | BTAF1 | 9044 | 2 | 6 | 22 | |
| GSE43470 | BTAF1 | 9044 | 0 | 8 | 35 | |
| GSE46452 | BTAF1 | 9044 | 0 | 11 | 48 | |
| GSE47630 | BTAF1 | 9044 | 2 | 14 | 24 | |
| GSE54993 | BTAF1 | 9044 | 7 | 0 | 63 | |
| GSE54994 | BTAF1 | 9044 | 1 | 10 | 42 | |
| GSE60625 | BTAF1 | 9044 | 0 | 0 | 11 | |
| GSE74703 | BTAF1 | 9044 | 0 | 6 | 30 | |
| GSE74704 | BTAF1 | 9044 | 0 | 4 | 16 | |
| TCGA | BTAF1 | 9044 | 7 | 27 | 62 |
Total number of gains: 21; Total number of losses: 93; Total Number of normals: 374.
Somatic mutations of BTAF1:
Generating mutation plots.
Highly correlated genes for BTAF1:
Showing top 20/480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTAF1 | RNF144B | 0.762526 | 3 | 0 | 3 |
| BTAF1 | KRR1 | 0.745046 | 3 | 0 | 3 |
| BTAF1 | ARL6 | 0.734357 | 3 | 0 | 3 |
| BTAF1 | WARS2 | 0.734169 | 3 | 0 | 3 |
| BTAF1 | RHBDD1 | 0.732541 | 3 | 0 | 3 |
| BTAF1 | PDE12 | 0.730153 | 4 | 0 | 4 |
| BTAF1 | GDAP2 | 0.724509 | 4 | 0 | 3 |
| BTAF1 | ZNF700 | 0.72241 | 3 | 0 | 3 |
| BTAF1 | FBXL17 | 0.721221 | 3 | 0 | 3 |
| BTAF1 | GET4 | 0.717871 | 3 | 0 | 3 |
| BTAF1 | PPP2R5E | 0.716671 | 4 | 0 | 4 |
| BTAF1 | DDX50 | 0.714116 | 3 | 0 | 3 |
| BTAF1 | ATG3 | 0.710328 | 3 | 0 | 3 |
| BTAF1 | ZNF506 | 0.707315 | 4 | 0 | 4 |
| BTAF1 | HINT3 | 0.70664 | 4 | 0 | 4 |
| BTAF1 | BCAS2 | 0.703598 | 3 | 0 | 3 |
| BTAF1 | HIPK3 | 0.700424 | 3 | 0 | 3 |
| BTAF1 | CHCHD1 | 0.699981 | 5 | 0 | 5 |
| BTAF1 | ZNF564 | 0.690698 | 3 | 0 | 3 |
| BTAF1 | CYB561 | 0.686344 | 3 | 0 | 3 |
For details and further investigation, click here
