| Full name: crystallin beta-gamma domain containing 3 | Alias Symbol: DKFZp667G2110 | ||
| Type: protein-coding gene | Cytoband: 3q11.2 | ||
| Entrez ID: 131544 | HGNC ID: HGNC:34427 | Ensembl Gene: ENSG00000080200 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CRYBG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYBG3 | 131544 | 214030_at | -0.8095 | 0.0924 | |
| GSE20347 | CRYBG3 | 131544 | 214030_at | -0.9384 | 0.0000 | |
| GSE23400 | CRYBG3 | 131544 | 214030_at | -0.4687 | 0.0000 | |
| GSE26886 | CRYBG3 | 131544 | 214030_at | -0.8049 | 0.0012 | |
| GSE29001 | CRYBG3 | 131544 | 214030_at | -0.8802 | 0.0007 | |
| GSE38129 | CRYBG3 | 131544 | 214030_at | -0.8107 | 0.0000 | |
| GSE45670 | CRYBG3 | 131544 | 214030_at | -0.5394 | 0.0003 | |
| GSE63941 | CRYBG3 | 131544 | 214030_at | -1.1424 | 0.0093 | |
| GSE77861 | CRYBG3 | 131544 | 214030_at | -0.9405 | 0.0063 | |
| GSE97050 | CRYBG3 | A_19_P00321202 | 0.0517 | 0.9111 | ||
| SRP007169 | CRYBG3 | 131544 | RNAseq | -0.5174 | 0.1566 | |
| SRP008496 | CRYBG3 | 131544 | RNAseq | -0.2067 | 0.4082 | |
| SRP064894 | CRYBG3 | 131544 | RNAseq | -1.3073 | 0.0107 | |
| SRP133303 | CRYBG3 | 131544 | RNAseq | -0.9191 | 0.0000 | |
| SRP159526 | CRYBG3 | 131544 | RNAseq | -1.1979 | 0.0132 | |
| SRP193095 | CRYBG3 | 131544 | RNAseq | -0.6502 | 0.0000 | |
| SRP219564 | CRYBG3 | 131544 | RNAseq | -1.6752 | 0.0067 | |
| TCGA | CRYBG3 | 131544 | RNAseq | -0.2285 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by CRYBG3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CRYBG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYBG3 | 131544 | 20 | 1 | 9 | |
| GSE20123 | CRYBG3 | 131544 | 19 | 1 | 10 | |
| GSE43470 | CRYBG3 | 131544 | 18 | 1 | 24 | |
| GSE46452 | CRYBG3 | 131544 | 12 | 7 | 40 | |
| GSE47630 | CRYBG3 | 131544 | 16 | 6 | 18 | |
| GSE54993 | CRYBG3 | 131544 | 2 | 6 | 62 | |
| GSE54994 | CRYBG3 | 131544 | 27 | 5 | 21 | |
| GSE60625 | CRYBG3 | 131544 | 0 | 6 | 5 | |
| GSE74703 | CRYBG3 | 131544 | 14 | 1 | 21 | |
| GSE74704 | CRYBG3 | 131544 | 14 | 1 | 5 | |
| TCGA | CRYBG3|ENSG00000080200.5 | NA | 51 | 11 | 34 |
Total number of gains: 193; Total number of losses: 46; Total Number of normals: 249.
Somatic mutations of CRYBG3:
Generating mutation plots.
Highly correlated genes for CRYBG3:
Showing top 20/1477 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYBG3 | TSPAN31 | 0.790004 | 3 | 0 | 3 |
| CRYBG3 | ZDHHC21 | 0.782354 | 4 | 0 | 4 |
| CRYBG3 | FAM122A | 0.776983 | 3 | 0 | 3 |
| CRYBG3 | SNORA68 | 0.774593 | 4 | 0 | 4 |
| CRYBG3 | ZNF681 | 0.770528 | 3 | 0 | 3 |
| CRYBG3 | UBE2F | 0.766808 | 3 | 0 | 3 |
| CRYBG3 | SMC5-AS1 | 0.757034 | 3 | 0 | 3 |
| CRYBG3 | VAPA | 0.753277 | 3 | 0 | 3 |
| CRYBG3 | MMEL1 | 0.752843 | 4 | 0 | 3 |
| CRYBG3 | MAGI3 | 0.751094 | 4 | 0 | 4 |
| CRYBG3 | ACPP | 0.750907 | 8 | 0 | 8 |
| CRYBG3 | FAM214A | 0.748473 | 4 | 0 | 4 |
| CRYBG3 | RAB11A | 0.747851 | 9 | 0 | 9 |
| CRYBG3 | TJP1 | 0.745439 | 9 | 0 | 9 |
| CRYBG3 | ZNF823 | 0.741607 | 5 | 0 | 5 |
| CRYBG3 | KLB | 0.741031 | 4 | 0 | 4 |
| CRYBG3 | RAB5A | 0.739909 | 9 | 0 | 9 |
| CRYBG3 | C5orf66-AS1 | 0.738302 | 5 | 0 | 5 |
| CRYBG3 | CAST | 0.7383 | 9 | 0 | 9 |
| CRYBG3 | SLC46A2 | 0.737914 | 5 | 0 | 5 |
For details and further investigation, click here
