| Full name: cytochrome b5 reductase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 1727 | HGNC ID: HGNC:2873 | Ensembl Gene: ENSG00000100243 | OMIM ID: 613213 |
| Drug and gene relationship at DGIdb | |||
Expression of CYB5R3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYB5R3 | 1727 | 201885_s_at | -0.1249 | 0.5462 | |
| GSE20347 | CYB5R3 | 1727 | 201885_s_at | 0.0464 | 0.7247 | |
| GSE23400 | CYB5R3 | 1727 | 201885_s_at | -0.0389 | 0.6186 | |
| GSE26886 | CYB5R3 | 1727 | 201885_s_at | 0.9421 | 0.0000 | |
| GSE29001 | CYB5R3 | 1727 | 201885_s_at | -0.1164 | 0.5961 | |
| GSE38129 | CYB5R3 | 1727 | 201885_s_at | -0.1599 | 0.3300 | |
| GSE45670 | CYB5R3 | 1727 | 201885_s_at | -0.2153 | 0.1041 | |
| GSE53622 | CYB5R3 | 1727 | 151909 | -0.0735 | 0.3243 | |
| GSE53624 | CYB5R3 | 1727 | 15363 | 0.1843 | 0.0001 | |
| GSE63941 | CYB5R3 | 1727 | 201885_s_at | -1.4180 | 0.0088 | |
| GSE77861 | CYB5R3 | 1727 | 201885_s_at | 0.3276 | 0.0752 | |
| GSE97050 | CYB5R3 | 1727 | A_24_P100277 | 0.2856 | 0.2185 | |
| SRP007169 | CYB5R3 | 1727 | RNAseq | 0.1139 | 0.7513 | |
| SRP008496 | CYB5R3 | 1727 | RNAseq | -0.0074 | 0.9725 | |
| SRP064894 | CYB5R3 | 1727 | RNAseq | 0.2063 | 0.2631 | |
| SRP133303 | CYB5R3 | 1727 | RNAseq | 0.1402 | 0.4261 | |
| SRP159526 | CYB5R3 | 1727 | RNAseq | 0.0111 | 0.9561 | |
| SRP193095 | CYB5R3 | 1727 | RNAseq | 0.4214 | 0.0088 | |
| SRP219564 | CYB5R3 | 1727 | RNAseq | 0.1066 | 0.8185 | |
| TCGA | CYB5R3 | 1727 | RNAseq | -0.0811 | 0.0369 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CYB5R3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYB5R3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYB5R3 | 1727 | 6 | 6 | 18 | |
| GSE20123 | CYB5R3 | 1727 | 6 | 5 | 19 | |
| GSE43470 | CYB5R3 | 1727 | 4 | 6 | 33 | |
| GSE46452 | CYB5R3 | 1727 | 31 | 2 | 26 | |
| GSE47630 | CYB5R3 | 1727 | 9 | 4 | 27 | |
| GSE54993 | CYB5R3 | 1727 | 3 | 6 | 61 | |
| GSE54994 | CYB5R3 | 1727 | 11 | 8 | 34 | |
| GSE60625 | CYB5R3 | 1727 | 5 | 0 | 6 | |
| GSE74703 | CYB5R3 | 1727 | 4 | 4 | 28 | |
| GSE74704 | CYB5R3 | 1727 | 3 | 3 | 14 | |
| TCGA | CYB5R3 | 1727 | 27 | 14 | 55 |
Total number of gains: 109; Total number of losses: 58; Total Number of normals: 321.
Somatic mutations of CYB5R3:
Generating mutation plots.
Highly correlated genes for CYB5R3:
Showing top 20/918 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYB5R3 | ZNF574 | 0.763642 | 4 | 0 | 4 |
| CYB5R3 | RPL19 | 0.748019 | 3 | 0 | 3 |
| CYB5R3 | GALNT15 | 0.700957 | 4 | 0 | 4 |
| CYB5R3 | LTBP2 | 0.698809 | 6 | 0 | 6 |
| CYB5R3 | TBX2 | 0.695619 | 3 | 0 | 3 |
| CYB5R3 | CNPY3 | 0.689591 | 3 | 0 | 3 |
| CYB5R3 | ZNF496 | 0.6817 | 3 | 0 | 3 |
| CYB5R3 | ASAP1 | 0.678312 | 3 | 0 | 3 |
| CYB5R3 | EDNRB | 0.675523 | 6 | 0 | 5 |
| CYB5R3 | COLEC12 | 0.672298 | 7 | 0 | 6 |
| CYB5R3 | B3GNT9 | 0.672203 | 5 | 0 | 5 |
| CYB5R3 | GDI1 | 0.671154 | 4 | 0 | 4 |
| CYB5R3 | C11orf96 | 0.667894 | 5 | 0 | 4 |
| CYB5R3 | RSPO3 | 0.666192 | 5 | 0 | 3 |
| CYB5R3 | TCF21 | 0.664871 | 5 | 0 | 5 |
| CYB5R3 | VIM | 0.663621 | 10 | 0 | 8 |
| CYB5R3 | SYNC | 0.663511 | 6 | 0 | 6 |
| CYB5R3 | TRIM47 | 0.663267 | 3 | 0 | 3 |
| CYB5R3 | DDX24 | 0.662617 | 5 | 0 | 4 |
| CYB5R3 | SSBP4 | 0.661762 | 4 | 0 | 3 |
For details and further investigation, click here
