| Full name: zinc finger protein 574 | Alias Symbol: FLJ22059 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 64763 | HGNC ID: HGNC:26166 | Ensembl Gene: ENSG00000105732 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNF574:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF574 | 64763 | 218762_at | 0.4172 | 0.4850 | |
| GSE20347 | ZNF574 | 64763 | 218762_at | -0.0111 | 0.9231 | |
| GSE23400 | ZNF574 | 64763 | 218762_at | -0.0344 | 0.4898 | |
| GSE26886 | ZNF574 | 64763 | 218762_at | 0.6795 | 0.0000 | |
| GSE29001 | ZNF574 | 64763 | 218762_at | 0.1805 | 0.7179 | |
| GSE38129 | ZNF574 | 64763 | 218762_at | 0.0302 | 0.7210 | |
| GSE45670 | ZNF574 | 64763 | 218762_at | 0.0241 | 0.8538 | |
| GSE53622 | ZNF574 | 64763 | 149706 | 0.0738 | 0.1697 | |
| GSE53624 | ZNF574 | 64763 | 149706 | 0.0612 | 0.3328 | |
| GSE63941 | ZNF574 | 64763 | 218762_at | 0.4407 | 0.0634 | |
| GSE77861 | ZNF574 | 64763 | 218762_at | 0.0250 | 0.9340 | |
| GSE97050 | ZNF574 | 64763 | A_23_P89931 | 0.3414 | 0.1857 | |
| SRP007169 | ZNF574 | 64763 | RNAseq | -0.6446 | 0.0858 | |
| SRP008496 | ZNF574 | 64763 | RNAseq | -0.3859 | 0.1660 | |
| SRP064894 | ZNF574 | 64763 | RNAseq | 0.1833 | 0.3963 | |
| SRP133303 | ZNF574 | 64763 | RNAseq | -0.0678 | 0.7615 | |
| SRP159526 | ZNF574 | 64763 | RNAseq | 0.2510 | 0.4803 | |
| SRP193095 | ZNF574 | 64763 | RNAseq | 0.0114 | 0.9159 | |
| SRP219564 | ZNF574 | 64763 | RNAseq | 0.2906 | 0.3521 | |
| TCGA | ZNF574 | 64763 | RNAseq | 0.0468 | 0.3606 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF574 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF574:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF574 | 64763 | 4 | 4 | 22 | |
| GSE20123 | ZNF574 | 64763 | 4 | 3 | 23 | |
| GSE43470 | ZNF574 | 64763 | 4 | 11 | 28 | |
| GSE46452 | ZNF574 | 64763 | 47 | 1 | 11 | |
| GSE47630 | ZNF574 | 64763 | 8 | 6 | 26 | |
| GSE54993 | ZNF574 | 64763 | 17 | 4 | 49 | |
| GSE54994 | ZNF574 | 64763 | 7 | 12 | 34 | |
| GSE60625 | ZNF574 | 64763 | 9 | 0 | 2 | |
| GSE74703 | ZNF574 | 64763 | 4 | 7 | 25 | |
| GSE74704 | ZNF574 | 64763 | 4 | 1 | 15 | |
| TCGA | ZNF574 | 64763 | 14 | 15 | 67 |
Total number of gains: 122; Total number of losses: 64; Total Number of normals: 302.
Somatic mutations of ZNF574:
Generating mutation plots.
Highly correlated genes for ZNF574:
Showing top 20/691 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF574 | ZNF628 | 0.837828 | 3 | 0 | 3 |
| ZNF574 | PPRC1 | 0.828815 | 3 | 0 | 3 |
| ZNF574 | CYB5R3 | 0.763642 | 4 | 0 | 4 |
| ZNF574 | PLXNA1 | 0.759888 | 3 | 0 | 3 |
| ZNF574 | PTPRK | 0.759852 | 3 | 0 | 3 |
| ZNF574 | SPSB1 | 0.752276 | 3 | 0 | 3 |
| ZNF574 | KHSRP | 0.744474 | 5 | 0 | 5 |
| ZNF574 | PRX | 0.742918 | 3 | 0 | 3 |
| ZNF574 | CBS | 0.742508 | 3 | 0 | 3 |
| ZNF574 | CBLB | 0.737072 | 3 | 0 | 3 |
| ZNF574 | TMEM184B | 0.735205 | 3 | 0 | 3 |
| ZNF574 | MYPOP | 0.730908 | 5 | 0 | 4 |
| ZNF574 | B3GNT9 | 0.728122 | 3 | 0 | 3 |
| ZNF574 | TIMM9 | 0.719609 | 3 | 0 | 3 |
| ZNF574 | ADAR | 0.71834 | 3 | 0 | 3 |
| ZNF574 | BRIX1 | 0.717454 | 3 | 0 | 3 |
| ZNF574 | MRPL55 | 0.715493 | 4 | 0 | 4 |
| ZNF574 | BMP8A | 0.713725 | 3 | 0 | 3 |
| ZNF574 | SSC5D | 0.712936 | 3 | 0 | 3 |
| ZNF574 | PARP12 | 0.712171 | 3 | 0 | 3 |
For details and further investigation, click here
