| Full name: cytohesin 1 | Alias Symbol: B2-1|D17S811E|cytohesin-1 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 9267 | HGNC ID: HGNC:9501 | Ensembl Gene: ENSG00000108669 | OMIM ID: 182115 |
| Drug and gene relationship at DGIdb | |||
CYTH1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04072 | Phospholipase D signaling pathway |
Expression of CYTH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYTH1 | 9267 | 202880_s_at | 0.0291 | 0.9713 | |
| GSE20347 | CYTH1 | 9267 | 202880_s_at | -0.1933 | 0.0847 | |
| GSE23400 | CYTH1 | 9267 | 202880_s_at | 0.0191 | 0.8519 | |
| GSE26886 | CYTH1 | 9267 | 202880_s_at | -0.6187 | 0.0004 | |
| GSE29001 | CYTH1 | 9267 | 202880_s_at | 0.0327 | 0.9178 | |
| GSE38129 | CYTH1 | 9267 | 202880_s_at | -0.0470 | 0.7769 | |
| GSE45670 | CYTH1 | 9267 | 202880_s_at | -0.0550 | 0.7559 | |
| GSE53622 | CYTH1 | 9267 | 532 | -0.4469 | 0.0000 | |
| GSE53624 | CYTH1 | 9267 | 532 | -0.3707 | 0.0000 | |
| GSE63941 | CYTH1 | 9267 | 202880_s_at | 0.7694 | 0.1282 | |
| GSE77861 | CYTH1 | 9267 | 202880_s_at | -0.0676 | 0.7849 | |
| GSE97050 | CYTH1 | 9267 | A_33_P3380405 | 0.3332 | 0.2750 | |
| SRP007169 | CYTH1 | 9267 | RNAseq | -0.8206 | 0.0293 | |
| SRP008496 | CYTH1 | 9267 | RNAseq | -0.9166 | 0.0000 | |
| SRP064894 | CYTH1 | 9267 | RNAseq | -0.3793 | 0.0019 | |
| SRP133303 | CYTH1 | 9267 | RNAseq | -0.4077 | 0.0000 | |
| SRP159526 | CYTH1 | 9267 | RNAseq | -0.6098 | 0.0008 | |
| SRP193095 | CYTH1 | 9267 | RNAseq | -0.4006 | 0.0089 | |
| SRP219564 | CYTH1 | 9267 | RNAseq | -0.2361 | 0.4784 | |
| TCGA | CYTH1 | 9267 | RNAseq | -0.0460 | 0.3392 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CYTH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYTH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYTH1 | 9267 | 4 | 3 | 23 | |
| GSE20123 | CYTH1 | 9267 | 4 | 3 | 23 | |
| GSE43470 | CYTH1 | 9267 | 3 | 4 | 36 | |
| GSE46452 | CYTH1 | 9267 | 33 | 0 | 26 | |
| GSE47630 | CYTH1 | 9267 | 8 | 1 | 31 | |
| GSE54993 | CYTH1 | 9267 | 2 | 5 | 63 | |
| GSE54994 | CYTH1 | 9267 | 10 | 5 | 38 | |
| GSE60625 | CYTH1 | 9267 | 6 | 0 | 5 | |
| GSE74703 | CYTH1 | 9267 | 3 | 2 | 31 | |
| GSE74704 | CYTH1 | 9267 | 4 | 3 | 13 | |
| TCGA | CYTH1 | 9267 | 29 | 9 | 58 |
Total number of gains: 106; Total number of losses: 35; Total Number of normals: 347.
Somatic mutations of CYTH1:
Generating mutation plots.
Highly correlated genes for CYTH1:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYTH1 | C6orf132 | 0.712086 | 3 | 0 | 3 |
| CYTH1 | GRIPAP1 | 0.703458 | 3 | 0 | 3 |
| CYTH1 | GPHA2 | 0.693206 | 3 | 0 | 3 |
| CYTH1 | SPAG4 | 0.688388 | 4 | 0 | 3 |
| CYTH1 | ADAMTS13 | 0.688376 | 3 | 0 | 3 |
| CYTH1 | GALNT5 | 0.673886 | 3 | 0 | 3 |
| CYTH1 | OTUB2 | 0.670788 | 5 | 0 | 4 |
| CYTH1 | PHLDB3 | 0.667156 | 5 | 0 | 4 |
| CYTH1 | PRPF6 | 0.657512 | 4 | 0 | 4 |
| CYTH1 | PLEKHN1 | 0.64916 | 3 | 0 | 3 |
| CYTH1 | RAET1E | 0.648644 | 3 | 0 | 3 |
| CYTH1 | HECTD1 | 0.644665 | 3 | 0 | 3 |
| CYTH1 | ADCK5 | 0.640348 | 3 | 0 | 3 |
| CYTH1 | RAB11FIP4 | 0.63826 | 5 | 0 | 4 |
| CYTH1 | BOK | 0.636373 | 3 | 0 | 3 |
| CYTH1 | AMN | 0.634786 | 4 | 0 | 3 |
| CYTH1 | TECPR1 | 0.629738 | 4 | 0 | 4 |
| CYTH1 | THEG | 0.629232 | 3 | 0 | 3 |
| CYTH1 | SEC13 | 0.626205 | 5 | 0 | 4 |
| CYTH1 | DEGS2 | 0.624896 | 4 | 0 | 3 |
For details and further investigation, click here
