| Full name: polypeptide N-acetylgalactosaminyltransferase 5 | Alias Symbol: GalNAc-T5 | ||
| Type: protein-coding gene | Cytoband: 2q24.1 | ||
| Entrez ID: 11227 | HGNC ID: HGNC:4127 | Ensembl Gene: ENSG00000136542 | OMIM ID: 615129 |
| Drug and gene relationship at DGIdb | |||
Expression of GALNT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALNT5 | 11227 | 229555_at | -0.5194 | 0.3797 | |
| GSE26886 | GALNT5 | 11227 | 229555_at | -1.9891 | 0.0000 | |
| GSE45670 | GALNT5 | 11227 | 229555_at | 0.0505 | 0.9052 | |
| GSE53622 | GALNT5 | 11227 | 16309 | -0.0399 | 0.8664 | |
| GSE53624 | GALNT5 | 11227 | 22885 | -1.3492 | 0.0000 | |
| GSE63941 | GALNT5 | 11227 | 229555_at | -1.8940 | 0.0377 | |
| GSE77861 | GALNT5 | 11227 | 229555_at | -0.6010 | 0.0020 | |
| GSE97050 | GALNT5 | 11227 | A_24_P408736 | 0.0661 | 0.9520 | |
| SRP007169 | GALNT5 | 11227 | RNAseq | -0.1616 | 0.8161 | |
| SRP008496 | GALNT5 | 11227 | RNAseq | -0.9779 | 0.0411 | |
| SRP064894 | GALNT5 | 11227 | RNAseq | -1.2017 | 0.0002 | |
| SRP133303 | GALNT5 | 11227 | RNAseq | -0.1518 | 0.6187 | |
| SRP159526 | GALNT5 | 11227 | RNAseq | -1.5145 | 0.0605 | |
| SRP193095 | GALNT5 | 11227 | RNAseq | -1.4958 | 0.0000 | |
| SRP219564 | GALNT5 | 11227 | RNAseq | -1.2602 | 0.1339 | |
| TCGA | GALNT5 | 11227 | RNAseq | -0.5977 | 0.0262 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by GALNT5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALNT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALNT5 | 11227 | 4 | 1 | 25 | |
| GSE20123 | GALNT5 | 11227 | 4 | 1 | 25 | |
| GSE43470 | GALNT5 | 11227 | 4 | 1 | 38 | |
| GSE46452 | GALNT5 | 11227 | 1 | 4 | 54 | |
| GSE47630 | GALNT5 | 11227 | 5 | 3 | 32 | |
| GSE54993 | GALNT5 | 11227 | 0 | 4 | 66 | |
| GSE54994 | GALNT5 | 11227 | 11 | 2 | 40 | |
| GSE60625 | GALNT5 | 11227 | 0 | 3 | 8 | |
| GSE74703 | GALNT5 | 11227 | 3 | 1 | 32 | |
| GSE74704 | GALNT5 | 11227 | 3 | 0 | 17 | |
| TCGA | GALNT5 | 11227 | 21 | 10 | 65 |
Total number of gains: 56; Total number of losses: 30; Total Number of normals: 402.
Somatic mutations of GALNT5:
Generating mutation plots.
Highly correlated genes for GALNT5:
Showing top 20/472 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALNT5 | ANKRD22 | 0.781901 | 3 | 0 | 3 |
| GALNT5 | SERPINB3 | 0.739695 | 3 | 0 | 3 |
| GALNT5 | CAPN14 | 0.737606 | 5 | 0 | 5 |
| GALNT5 | KRT80 | 0.73472 | 3 | 0 | 3 |
| GALNT5 | SPNS2 | 0.70729 | 4 | 0 | 3 |
| GALNT5 | SPAG17 | 0.70691 | 4 | 0 | 4 |
| GALNT5 | FAM3D | 0.7025 | 5 | 0 | 4 |
| GALNT5 | ANXA9 | 0.702344 | 5 | 0 | 5 |
| GALNT5 | CLIC3 | 0.697447 | 4 | 0 | 3 |
| GALNT5 | PTK6 | 0.692498 | 6 | 0 | 6 |
| GALNT5 | GBP6 | 0.686817 | 4 | 0 | 3 |
| GALNT5 | CCR6 | 0.686471 | 3 | 0 | 3 |
| GALNT5 | GALK1 | 0.684678 | 3 | 0 | 3 |
| GALNT5 | KRT78 | 0.683375 | 6 | 0 | 6 |
| GALNT5 | GCHFR | 0.682095 | 5 | 0 | 4 |
| GALNT5 | ABLIM1 | 0.681276 | 5 | 0 | 4 |
| GALNT5 | KLK12 | 0.679476 | 4 | 0 | 3 |
| GALNT5 | CYSRT1 | 0.678884 | 5 | 0 | 5 |
| GALNT5 | RAB10 | 0.675685 | 5 | 0 | 4 |
| GALNT5 | TTC9 | 0.675531 | 5 | 0 | 4 |
For details and further investigation, click here
