| Full name: aarF domain containing kinase 5 | Alias Symbol: FLJ35454 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 203054 | HGNC ID: HGNC:21738 | Ensembl Gene: ENSG00000173137 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADCK5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADCK5 | 203054 | 228524_at | 0.4788 | 0.1665 | |
| GSE26886 | ADCK5 | 203054 | 228524_at | 0.2854 | 0.0462 | |
| GSE45670 | ADCK5 | 203054 | 228524_at | 0.2859 | 0.0304 | |
| GSE53622 | ADCK5 | 203054 | 79707 | 0.2818 | 0.0114 | |
| GSE53624 | ADCK5 | 203054 | 79707 | 0.4112 | 0.0000 | |
| GSE63941 | ADCK5 | 203054 | 228524_at | 0.4864 | 0.1987 | |
| GSE77861 | ADCK5 | 203054 | 228524_at | 0.0562 | 0.8150 | |
| GSE97050 | ADCK5 | 203054 | A_23_P94365 | 0.1201 | 0.5515 | |
| SRP007169 | ADCK5 | 203054 | RNAseq | -0.5300 | 0.3412 | |
| SRP008496 | ADCK5 | 203054 | RNAseq | 0.0283 | 0.9467 | |
| SRP064894 | ADCK5 | 203054 | RNAseq | 1.2433 | 0.0000 | |
| SRP133303 | ADCK5 | 203054 | RNAseq | 0.2701 | 0.1273 | |
| SRP159526 | ADCK5 | 203054 | RNAseq | -0.0300 | 0.9159 | |
| SRP193095 | ADCK5 | 203054 | RNAseq | 0.2794 | 0.0727 | |
| SRP219564 | ADCK5 | 203054 | RNAseq | 0.3812 | 0.4254 | |
| TCGA | ADCK5 | 203054 | RNAseq | 0.3654 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ADCK5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADCK5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADCK5 | 203054 | 17 | 1 | 12 | |
| GSE20123 | ADCK5 | 203054 | 17 | 1 | 12 | |
| GSE43470 | ADCK5 | 203054 | 16 | 2 | 25 | |
| GSE46452 | ADCK5 | 203054 | 28 | 0 | 31 | |
| GSE47630 | ADCK5 | 203054 | 25 | 1 | 14 | |
| GSE54993 | ADCK5 | 203054 | 0 | 25 | 45 | |
| GSE54994 | ADCK5 | 203054 | 39 | 1 | 13 | |
| GSE60625 | ADCK5 | 203054 | 3 | 4 | 4 | |
| GSE74703 | ADCK5 | 203054 | 14 | 1 | 21 | |
| GSE74704 | ADCK5 | 203054 | 10 | 0 | 10 | |
| TCGA | ADCK5 | 203054 | 63 | 2 | 31 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of ADCK5:
Generating mutation plots.
Highly correlated genes for ADCK5:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADCK5 | CD70 | 0.738669 | 3 | 0 | 3 |
| ADCK5 | TRIM31 | 0.7141 | 3 | 0 | 3 |
| ADCK5 | PKLR | 0.712564 | 3 | 0 | 3 |
| ADCK5 | SLC22A13 | 0.709486 | 3 | 0 | 3 |
| ADCK5 | SPAG4 | 0.706903 | 3 | 0 | 3 |
| ADCK5 | MICALL2 | 0.702969 | 4 | 0 | 3 |
| ADCK5 | FERMT3 | 0.692088 | 3 | 0 | 3 |
| ADCK5 | ST3GAL1 | 0.69177 | 4 | 0 | 3 |
| ADCK5 | DNAL4 | 0.690584 | 3 | 0 | 3 |
| ADCK5 | FBXO15 | 0.686683 | 3 | 0 | 3 |
| ADCK5 | TMEM9 | 0.684036 | 3 | 0 | 3 |
| ADCK5 | CPNE9 | 0.680254 | 3 | 0 | 3 |
| ADCK5 | TONSL | 0.675032 | 5 | 0 | 5 |
| ADCK5 | PHF21A | 0.673204 | 3 | 0 | 3 |
| ADCK5 | ZBTB7B | 0.67001 | 3 | 0 | 3 |
| ADCK5 | GNLY | 0.665286 | 3 | 0 | 3 |
| ADCK5 | SOX12 | 0.664948 | 4 | 0 | 3 |
| ADCK5 | PTPRCAP | 0.660028 | 3 | 0 | 3 |
| ADCK5 | SURF2 | 0.657636 | 4 | 0 | 3 |
| ADCK5 | CHMP1A | 0.657183 | 4 | 0 | 3 |
For details and further investigation, click here
