| Full name: doublecortin domain containing 2 | Alias Symbol: RU2|KIAA1154|DCDC2A|NPHP19 | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 51473 | HGNC ID: HGNC:18141 | Ensembl Gene: ENSG00000146038 | OMIM ID: 605755 |
| Drug and gene relationship at DGIdb | |||
Expression of DCDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCDC2 | 51473 | 222925_at | 0.1291 | 0.8934 | |
| GSE26886 | DCDC2 | 51473 | 222926_at | 0.1213 | 0.2487 | |
| GSE45670 | DCDC2 | 51473 | 222925_at | -0.0733 | 0.3542 | |
| GSE53622 | DCDC2 | 51473 | 169232 | -0.1236 | 0.4621 | |
| GSE53624 | DCDC2 | 51473 | 169232 | -0.3807 | 0.0128 | |
| GSE63941 | DCDC2 | 51473 | 222925_at | -0.0869 | 0.8112 | |
| GSE77861 | DCDC2 | 51473 | 222925_at | -0.1506 | 0.0896 | |
| SRP133303 | DCDC2 | 51473 | RNAseq | -0.7813 | 0.0675 | |
| TCGA | DCDC2 | 51473 | RNAseq | -3.0759 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DCDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCDC2 | 51473 | 4 | 2 | 24 | |
| GSE20123 | DCDC2 | 51473 | 4 | 2 | 24 | |
| GSE43470 | DCDC2 | 51473 | 6 | 0 | 37 | |
| GSE46452 | DCDC2 | 51473 | 1 | 9 | 49 | |
| GSE47630 | DCDC2 | 51473 | 8 | 5 | 27 | |
| GSE54993 | DCDC2 | 51473 | 1 | 1 | 68 | |
| GSE54994 | DCDC2 | 51473 | 11 | 4 | 38 | |
| GSE60625 | DCDC2 | 51473 | 0 | 1 | 10 | |
| GSE74703 | DCDC2 | 51473 | 6 | 0 | 30 | |
| GSE74704 | DCDC2 | 51473 | 1 | 1 | 18 | |
| TCGA | DCDC2 | 51473 | 17 | 20 | 59 |
Total number of gains: 59; Total number of losses: 45; Total Number of normals: 384.
Somatic mutations of DCDC2:
Generating mutation plots.
Highly correlated genes for DCDC2:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCDC2 | ACTL8 | 0.657718 | 3 | 0 | 3 |
| DCDC2 | MUC5B | 0.63245 | 4 | 0 | 3 |
| DCDC2 | TFF1 | 0.615294 | 5 | 0 | 5 |
| DCDC2 | KRT7 | 0.612958 | 4 | 0 | 3 |
| DCDC2 | TMPRSS3 | 0.609781 | 3 | 0 | 3 |
| DCDC2 | BLOC1S1 | 0.585298 | 3 | 0 | 3 |
| DCDC2 | LAT | 0.577985 | 4 | 0 | 4 |
| DCDC2 | LRRC6 | 0.563304 | 3 | 0 | 3 |
| DCDC2 | SCGB1D2 | 0.561471 | 4 | 0 | 3 |
| DCDC2 | SLC44A4 | 0.556993 | 6 | 0 | 3 |
| DCDC2 | GNMT | 0.555866 | 4 | 0 | 3 |
| DCDC2 | CAPN8 | 0.543704 | 5 | 0 | 3 |
| DCDC2 | TESC | 0.542396 | 4 | 0 | 3 |
| DCDC2 | C6orf58 | 0.540836 | 4 | 0 | 3 |
| DCDC2 | NANS | 0.530546 | 4 | 0 | 3 |
| DCDC2 | MLPH | 0.522473 | 4 | 0 | 3 |
For details and further investigation, click here
