| Full name: solute carrier family 44 member 4 | Alias Symbol: NG22|CTL4|FLJ14491|TPPT|DFNA72 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 80736 | HGNC ID: HGNC:13941 | Ensembl Gene: ENSG00000204385 | OMIM ID: 606107 |
| Drug and gene relationship at DGIdb | |||
SLC44A4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05231 | Choline metabolism in cancer |
Expression of SLC44A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC44A4 | 80736 | 205597_at | -0.0413 | 0.9822 | |
| GSE20347 | SLC44A4 | 80736 | 205597_at | -0.0699 | 0.2476 | |
| GSE23400 | SLC44A4 | 80736 | 205597_at | -0.0696 | 0.1567 | |
| GSE26886 | SLC44A4 | 80736 | 1555203_s_at | -0.0003 | 0.9978 | |
| GSE29001 | SLC44A4 | 80736 | 205597_at | 0.0552 | 0.7258 | |
| GSE38129 | SLC44A4 | 80736 | 205597_at | -0.2267 | 0.1153 | |
| GSE45670 | SLC44A4 | 80736 | 205597_at | -0.2533 | 0.2308 | |
| GSE53622 | SLC44A4 | 80736 | 10845 | -0.8288 | 0.0228 | |
| GSE53624 | SLC44A4 | 80736 | 10845 | -1.2948 | 0.0000 | |
| GSE63941 | SLC44A4 | 80736 | 205597_at | 0.7162 | 0.5607 | |
| GSE77861 | SLC44A4 | 80736 | 205597_at | -0.1195 | 0.3570 | |
| GSE97050 | SLC44A4 | 80736 | A_24_P684183 | 0.1593 | 0.8432 | |
| SRP133303 | SLC44A4 | 80736 | RNAseq | -1.8381 | 0.0028 | |
| SRP159526 | SLC44A4 | 80736 | RNAseq | -1.0311 | 0.2852 | |
| SRP193095 | SLC44A4 | 80736 | RNAseq | -1.3673 | 0.0828 | |
| TCGA | SLC44A4 | 80736 | RNAseq | -2.1230 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SLC44A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC44A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC44A4 | 80736 | 5 | 1 | 24 | |
| GSE20123 | SLC44A4 | 80736 | 5 | 1 | 24 | |
| GSE43470 | SLC44A4 | 80736 | 5 | 1 | 37 | |
| GSE46452 | SLC44A4 | 80736 | 1 | 10 | 48 | |
| GSE47630 | SLC44A4 | 80736 | 7 | 4 | 29 | |
| GSE54993 | SLC44A4 | 80736 | 2 | 1 | 67 | |
| GSE54994 | SLC44A4 | 80736 | 11 | 4 | 38 | |
| GSE60625 | SLC44A4 | 80736 | 0 | 1 | 10 | |
| GSE74703 | SLC44A4 | 80736 | 5 | 0 | 31 | |
| GSE74704 | SLC44A4 | 80736 | 2 | 0 | 18 | |
| TCGA | SLC44A4 | 80736 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of SLC44A4:
Generating mutation plots.
Highly correlated genes for SLC44A4:
Showing top 20/206 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC44A4 | FKTN | 0.806331 | 3 | 0 | 3 |
| SLC44A4 | CASP9 | 0.805171 | 3 | 0 | 3 |
| SLC44A4 | SRRM1 | 0.796791 | 3 | 0 | 3 |
| SLC44A4 | GDPD1 | 0.76278 | 3 | 0 | 3 |
| SLC44A4 | ARL16 | 0.746396 | 3 | 0 | 3 |
| SLC44A4 | SUFU | 0.742784 | 3 | 0 | 3 |
| SLC44A4 | BPIFB1 | 0.741401 | 4 | 0 | 4 |
| SLC44A4 | ACP6 | 0.725021 | 3 | 0 | 3 |
| SLC44A4 | ZNF578 | 0.720498 | 3 | 0 | 3 |
| SLC44A4 | USP48 | 0.714464 | 3 | 0 | 3 |
| SLC44A4 | LINC00271 | 0.700988 | 3 | 0 | 3 |
| SLC44A4 | CXCR5 | 0.698749 | 3 | 0 | 3 |
| SLC44A4 | TSPAN3 | 0.696614 | 3 | 0 | 3 |
| SLC44A4 | CLCN7 | 0.696189 | 3 | 0 | 3 |
| SLC44A4 | KRT33B | 0.694381 | 3 | 0 | 3 |
| SLC44A4 | CTDSP1 | 0.692453 | 3 | 0 | 3 |
| SLC44A4 | TCF25 | 0.687005 | 3 | 0 | 3 |
| SLC44A4 | KIAA2013 | 0.686761 | 3 | 0 | 3 |
| SLC44A4 | MKRN1 | 0.686091 | 3 | 0 | 3 |
| SLC44A4 | NAIF1 | 0.684871 | 4 | 0 | 4 |
For details and further investigation, click here
