| Full name: defective in cullin neddylation 1 domain containing 1 | Alias Symbol: RP42|SCRO|DCUN1L1|Tes3|SCCRO | ||
| Type: protein-coding gene | Cytoband: 3q26.33 | ||
| Entrez ID: 54165 | HGNC ID: HGNC:18184 | Ensembl Gene: ENSG00000043093 | OMIM ID: 605905 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DCUN1D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCUN1D1 | 54165 | 218583_s_at | 0.2304 | 0.5143 | |
| GSE20347 | DCUN1D1 | 54165 | 218583_s_at | 0.2860 | 0.0136 | |
| GSE23400 | DCUN1D1 | 54165 | 218583_s_at | 0.3733 | 0.0000 | |
| GSE26886 | DCUN1D1 | 54165 | 218583_s_at | -0.1417 | 0.6258 | |
| GSE29001 | DCUN1D1 | 54165 | 218583_s_at | 0.4071 | 0.1141 | |
| GSE38129 | DCUN1D1 | 54165 | 218583_s_at | 0.3600 | 0.0016 | |
| GSE45670 | DCUN1D1 | 54165 | 218583_s_at | 0.2075 | 0.3215 | |
| GSE53622 | DCUN1D1 | 54165 | 44748 | 0.5607 | 0.0000 | |
| GSE53624 | DCUN1D1 | 54165 | 44748 | 0.4351 | 0.0000 | |
| GSE63941 | DCUN1D1 | 54165 | 218583_s_at | 0.8259 | 0.1903 | |
| GSE77861 | DCUN1D1 | 54165 | 218583_s_at | 0.1684 | 0.6277 | |
| GSE97050 | DCUN1D1 | A_21_P0003308 | -0.3347 | 0.2659 | ||
| SRP007169 | DCUN1D1 | 54165 | RNAseq | 0.2741 | 0.5692 | |
| SRP008496 | DCUN1D1 | 54165 | RNAseq | 0.3527 | 0.2510 | |
| SRP064894 | DCUN1D1 | 54165 | RNAseq | -0.0456 | 0.8150 | |
| SRP133303 | DCUN1D1 | 54165 | RNAseq | 0.7584 | 0.0001 | |
| SRP159526 | DCUN1D1 | 54165 | RNAseq | 1.1214 | 0.0010 | |
| SRP193095 | DCUN1D1 | 54165 | RNAseq | 0.1729 | 0.2142 | |
| SRP219564 | DCUN1D1 | 54165 | RNAseq | -0.5149 | 0.1287 | |
| TCGA | DCUN1D1 | 54165 | RNAseq | 0.2316 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DCUN1D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCUN1D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCUN1D1 | 54165 | 25 | 0 | 5 | |
| GSE20123 | DCUN1D1 | 54165 | 25 | 0 | 5 | |
| GSE43470 | DCUN1D1 | 54165 | 24 | 0 | 19 | |
| GSE46452 | DCUN1D1 | 54165 | 19 | 1 | 39 | |
| GSE47630 | DCUN1D1 | 54165 | 27 | 2 | 11 | |
| GSE54993 | DCUN1D1 | 54165 | 1 | 19 | 50 | |
| GSE54994 | DCUN1D1 | 54165 | 40 | 0 | 13 | |
| GSE60625 | DCUN1D1 | 54165 | 0 | 6 | 5 | |
| GSE74703 | DCUN1D1 | 54165 | 20 | 0 | 16 | |
| GSE74704 | DCUN1D1 | 54165 | 17 | 0 | 3 | |
| TCGA | DCUN1D1 | 54165 | 77 | 0 | 19 |
Total number of gains: 275; Total number of losses: 28; Total Number of normals: 185.
Somatic mutations of DCUN1D1:
Generating mutation plots.
Highly correlated genes for DCUN1D1:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCUN1D1 | HOGA1 | 0.838502 | 3 | 0 | 3 |
| DCUN1D1 | LINC01133 | 0.691324 | 3 | 0 | 3 |
| DCUN1D1 | ZNF624 | 0.667542 | 3 | 0 | 3 |
| DCUN1D1 | PDCL | 0.65059 | 4 | 0 | 3 |
| DCUN1D1 | LYPD6 | 0.64703 | 4 | 0 | 3 |
| DCUN1D1 | ZNF639 | 0.640943 | 10 | 0 | 8 |
| DCUN1D1 | ZBTB24 | 0.640827 | 4 | 0 | 3 |
| DCUN1D1 | RAD51 | 0.629639 | 6 | 0 | 4 |
| DCUN1D1 | KIAA1671 | 0.619212 | 4 | 0 | 3 |
| DCUN1D1 | DMP1 | 0.617625 | 3 | 0 | 3 |
| DCUN1D1 | ZNF629 | 0.615979 | 3 | 0 | 3 |
| DCUN1D1 | SNRNP40 | 0.606929 | 3 | 0 | 3 |
| DCUN1D1 | CDK1 | 0.601134 | 5 | 0 | 4 |
| DCUN1D1 | TIMMDC1 | 0.598616 | 4 | 0 | 3 |
| DCUN1D1 | HMBS | 0.597843 | 5 | 0 | 3 |
| DCUN1D1 | CHRNA5 | 0.577102 | 5 | 0 | 3 |
| DCUN1D1 | POLR2H | 0.575427 | 9 | 0 | 7 |
| DCUN1D1 | ETAA1 | 0.575426 | 7 | 0 | 5 |
| DCUN1D1 | HS2ST1 | 0.569858 | 5 | 0 | 3 |
| DCUN1D1 | ENOX2 | 0.568659 | 7 | 0 | 4 |
For details and further investigation, click here
