| Full name: phosducin like | Alias Symbol: PhLP|DKFZp564M1863 | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 5082 | HGNC ID: HGNC:8770 | Ensembl Gene: ENSG00000136940 | OMIM ID: 604421 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PDCL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDCL | 5082 | 204449_at | 0.1816 | 0.7598 | |
| GSE20347 | PDCL | 5082 | 204449_at | -0.1598 | 0.2994 | |
| GSE23400 | PDCL | 5082 | 204448_s_at | 0.3005 | 0.0000 | |
| GSE26886 | PDCL | 5082 | 204449_at | 0.1752 | 0.1627 | |
| GSE29001 | PDCL | 5082 | 204449_at | 0.4649 | 0.0404 | |
| GSE38129 | PDCL | 5082 | 204449_at | 0.0031 | 0.9817 | |
| GSE45670 | PDCL | 5082 | 204449_at | 0.1056 | 0.4375 | |
| GSE53622 | PDCL | 5082 | 61889 | 0.1513 | 0.0063 | |
| GSE53624 | PDCL | 5082 | 61889 | 0.2364 | 0.0000 | |
| GSE63941 | PDCL | 5082 | 204449_at | -0.6182 | 0.0594 | |
| GSE77861 | PDCL | 5082 | 204448_s_at | 0.2980 | 0.1765 | |
| GSE97050 | PDCL | 5082 | A_33_P3405360 | 0.1055 | 0.5824 | |
| SRP007169 | PDCL | 5082 | RNAseq | 0.4567 | 0.3127 | |
| SRP008496 | PDCL | 5082 | RNAseq | 0.7667 | 0.0035 | |
| SRP064894 | PDCL | 5082 | RNAseq | 0.3629 | 0.0196 | |
| SRP133303 | PDCL | 5082 | RNAseq | 0.2264 | 0.1018 | |
| SRP159526 | PDCL | 5082 | RNAseq | 0.1137 | 0.5932 | |
| SRP193095 | PDCL | 5082 | RNAseq | 0.0116 | 0.9211 | |
| SRP219564 | PDCL | 5082 | RNAseq | 0.0015 | 0.9964 | |
| TCGA | PDCL | 5082 | RNAseq | 0.1202 | 0.0420 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDCL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDCL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDCL | 5082 | 3 | 9 | 18 | |
| GSE20123 | PDCL | 5082 | 3 | 9 | 18 | |
| GSE43470 | PDCL | 5082 | 5 | 3 | 35 | |
| GSE46452 | PDCL | 5082 | 6 | 13 | 40 | |
| GSE47630 | PDCL | 5082 | 3 | 16 | 21 | |
| GSE54993 | PDCL | 5082 | 3 | 3 | 64 | |
| GSE54994 | PDCL | 5082 | 9 | 10 | 34 | |
| GSE60625 | PDCL | 5082 | 0 | 0 | 11 | |
| GSE74703 | PDCL | 5082 | 5 | 3 | 28 | |
| GSE74704 | PDCL | 5082 | 2 | 6 | 12 | |
| TCGA | PDCL | 5082 | 28 | 24 | 44 |
Total number of gains: 67; Total number of losses: 96; Total Number of normals: 325.
Somatic mutations of PDCL:
Generating mutation plots.
Highly correlated genes for PDCL:
Showing top 20/47 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDCL | LTB4R | 0.717815 | 3 | 0 | 3 |
| PDCL | RFT1 | 0.697702 | 3 | 0 | 3 |
| PDCL | WDPCP | 0.680554 | 3 | 0 | 3 |
| PDCL | ZNF501 | 0.677178 | 3 | 0 | 3 |
| PDCL | RAG2 | 0.663295 | 4 | 0 | 3 |
| PDCL | APTX | 0.661763 | 5 | 0 | 5 |
| PDCL | CCDC142 | 0.660362 | 3 | 0 | 3 |
| PDCL | DCUN1D1 | 0.65059 | 4 | 0 | 3 |
| PDCL | FOLR3 | 0.635808 | 3 | 0 | 3 |
| PDCL | MRPS2 | 0.63201 | 5 | 0 | 3 |
| PDCL | GOLGA1 | 0.620212 | 3 | 0 | 3 |
| PDCL | CCDC43 | 0.612188 | 4 | 0 | 3 |
| PDCL | HIVEP2 | 0.610385 | 6 | 0 | 3 |
| PDCL | METTL4 | 0.603351 | 5 | 0 | 3 |
| PDCL | TCHH | 0.602653 | 4 | 0 | 3 |
| PDCL | ATG16L1 | 0.60085 | 5 | 0 | 3 |
| PDCL | NIFK | 0.593995 | 3 | 0 | 3 |
| PDCL | LAMTOR2 | 0.588546 | 4 | 0 | 3 |
| PDCL | TMCO3 | 0.577351 | 4 | 0 | 3 |
| PDCL | INIP | 0.572528 | 5 | 0 | 4 |
For details and further investigation, click here
