| Full name: ETAA1 activator of ATR kinase | Alias Symbol: ETAA16 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 54465 | HGNC ID: HGNC:24648 | Ensembl Gene: ENSG00000143971 | OMIM ID: 613196 |
| Drug and gene relationship at DGIdb | |||
Expression of ETAA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETAA1 | 54465 | 219216_at | 0.0359 | 0.9494 | |
| GSE20347 | ETAA1 | 54465 | 219216_at | 0.2762 | 0.0016 | |
| GSE23400 | ETAA1 | 54465 | 219216_at | 0.1997 | 0.0000 | |
| GSE26886 | ETAA1 | 54465 | 219216_at | 0.5622 | 0.0168 | |
| GSE29001 | ETAA1 | 54465 | 219216_at | 0.1899 | 0.6067 | |
| GSE38129 | ETAA1 | 54465 | 219216_at | 0.3147 | 0.0016 | |
| GSE45670 | ETAA1 | 54465 | 219216_at | 0.1366 | 0.3751 | |
| GSE53622 | ETAA1 | 54465 | 90403 | 0.4030 | 0.0000 | |
| GSE53624 | ETAA1 | 54465 | 90403 | 0.2815 | 0.0000 | |
| GSE63941 | ETAA1 | 54465 | 219216_at | -0.3473 | 0.5218 | |
| GSE77861 | ETAA1 | 54465 | 219216_at | 0.2370 | 0.1780 | |
| GSE97050 | ETAA1 | 54465 | A_23_P51117 | 0.4269 | 0.2261 | |
| SRP007169 | ETAA1 | 54465 | RNAseq | 0.2419 | 0.5315 | |
| SRP008496 | ETAA1 | 54465 | RNAseq | 0.5444 | 0.0271 | |
| SRP064894 | ETAA1 | 54465 | RNAseq | 0.2410 | 0.2116 | |
| SRP133303 | ETAA1 | 54465 | RNAseq | 0.5824 | 0.0002 | |
| SRP159526 | ETAA1 | 54465 | RNAseq | 0.3911 | 0.1724 | |
| SRP193095 | ETAA1 | 54465 | RNAseq | 0.1404 | 0.2831 | |
| SRP219564 | ETAA1 | 54465 | RNAseq | 0.1221 | 0.7557 | |
| TCGA | ETAA1 | 54465 | RNAseq | 0.1597 | 0.0055 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ETAA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETAA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETAA1 | 54465 | 12 | 0 | 18 | |
| GSE20123 | ETAA1 | 54465 | 11 | 0 | 19 | |
| GSE43470 | ETAA1 | 54465 | 6 | 0 | 37 | |
| GSE46452 | ETAA1 | 54465 | 2 | 3 | 54 | |
| GSE47630 | ETAA1 | 54465 | 8 | 0 | 32 | |
| GSE54993 | ETAA1 | 54465 | 0 | 6 | 64 | |
| GSE54994 | ETAA1 | 54465 | 12 | 0 | 41 | |
| GSE60625 | ETAA1 | 54465 | 0 | 3 | 8 | |
| GSE74703 | ETAA1 | 54465 | 6 | 0 | 30 | |
| GSE74704 | ETAA1 | 54465 | 9 | 0 | 11 | |
| TCGA | ETAA1 | 54465 | 36 | 2 | 58 |
Total number of gains: 102; Total number of losses: 14; Total Number of normals: 372.
Somatic mutations of ETAA1:
Generating mutation plots.
Highly correlated genes for ETAA1:
Showing top 20/167 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETAA1 | ALOX12B | 0.726958 | 3 | 0 | 3 |
| ETAA1 | PIGW | 0.660064 | 3 | 0 | 3 |
| ETAA1 | FBXO22 | 0.657 | 5 | 0 | 4 |
| ETAA1 | CCDC34 | 0.632585 | 5 | 0 | 4 |
| ETAA1 | PRMT5 | 0.625812 | 5 | 0 | 4 |
| ETAA1 | RBBP8 | 0.621519 | 8 | 0 | 7 |
| ETAA1 | C15orf40 | 0.620641 | 4 | 0 | 3 |
| ETAA1 | ICE2 | 0.620448 | 6 | 0 | 5 |
| ETAA1 | PRPF40A | 0.618942 | 8 | 0 | 7 |
| ETAA1 | TTC32 | 0.617256 | 4 | 0 | 4 |
| ETAA1 | ATRAID | 0.6167 | 8 | 0 | 8 |
| ETAA1 | MGME1 | 0.61503 | 4 | 0 | 3 |
| ETAA1 | LRRC57 | 0.611687 | 4 | 0 | 3 |
| ETAA1 | TBC1D7 | 0.608287 | 5 | 0 | 3 |
| ETAA1 | POLQ | 0.605515 | 7 | 0 | 4 |
| ETAA1 | PRMT3 | 0.603687 | 8 | 0 | 7 |
| ETAA1 | ST8SIA1 | 0.59802 | 3 | 0 | 3 |
| ETAA1 | LRR1 | 0.59785 | 5 | 0 | 3 |
| ETAA1 | PDCD11 | 0.596529 | 4 | 0 | 3 |
| ETAA1 | EPB41L4B | 0.595378 | 6 | 0 | 3 |
For details and further investigation, click here
