| Full name: DEAD-box helicase 23 | Alias Symbol: prp28|U5-100K|PRPF28|SNRNP100 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 9416 | HGNC ID: HGNC:17347 | Ensembl Gene: ENSG00000174243 | OMIM ID: 612172 |
| Drug and gene relationship at DGIdb | |||
Expression of DDX23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX23 | 9416 | 40465_at | 0.2957 | 0.3865 | |
| GSE20347 | DDX23 | 9416 | 40465_at | 0.2203 | 0.0102 | |
| GSE23400 | DDX23 | 9416 | 201440_at | 0.2382 | 0.0000 | |
| GSE26886 | DDX23 | 9416 | 40465_at | -0.4360 | 0.0247 | |
| GSE29001 | DDX23 | 9416 | 40465_at | 0.2496 | 0.2130 | |
| GSE38129 | DDX23 | 9416 | 40465_at | 0.2798 | 0.0001 | |
| GSE45670 | DDX23 | 9416 | 40465_at | 0.3036 | 0.0005 | |
| GSE53622 | DDX23 | 9416 | 23346 | 0.2986 | 0.0000 | |
| GSE53624 | DDX23 | 9416 | 23346 | 0.4443 | 0.0000 | |
| GSE63941 | DDX23 | 9416 | 40465_at | 0.6724 | 0.0868 | |
| GSE77861 | DDX23 | 9416 | 201440_at | 0.4316 | 0.0029 | |
| GSE97050 | DDX23 | 9416 | A_23_P64770 | 0.3786 | 0.1813 | |
| SRP007169 | DDX23 | 9416 | RNAseq | 2.2090 | 0.0016 | |
| SRP008496 | DDX23 | 9416 | RNAseq | 1.8062 | 0.0001 | |
| SRP064894 | DDX23 | 9416 | RNAseq | 0.3122 | 0.0011 | |
| SRP133303 | DDX23 | 9416 | RNAseq | 0.3649 | 0.0234 | |
| SRP159526 | DDX23 | 9416 | RNAseq | 0.1818 | 0.3326 | |
| SRP193095 | DDX23 | 9416 | RNAseq | 0.2537 | 0.0007 | |
| SRP219564 | DDX23 | 9416 | RNAseq | 0.1281 | 0.5822 | |
| TCGA | DDX23 | 9416 | RNAseq | 0.0170 | 0.6946 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DDX23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX23 | 9416 | 6 | 1 | 23 | |
| GSE20123 | DDX23 | 9416 | 6 | 1 | 23 | |
| GSE43470 | DDX23 | 9416 | 4 | 1 | 38 | |
| GSE46452 | DDX23 | 9416 | 8 | 1 | 50 | |
| GSE47630 | DDX23 | 9416 | 11 | 2 | 27 | |
| GSE54993 | DDX23 | 9416 | 0 | 5 | 65 | |
| GSE54994 | DDX23 | 9416 | 6 | 1 | 46 | |
| GSE60625 | DDX23 | 9416 | 0 | 0 | 11 | |
| GSE74703 | DDX23 | 9416 | 4 | 1 | 31 | |
| GSE74704 | DDX23 | 9416 | 4 | 1 | 15 | |
| TCGA | DDX23 | 9416 | 16 | 12 | 68 |
Total number of gains: 65; Total number of losses: 26; Total Number of normals: 397.
Somatic mutations of DDX23:
Generating mutation plots.
Highly correlated genes for DDX23:
Showing top 20/1166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX23 | UCKL1 | 0.81739 | 3 | 0 | 3 |
| DDX23 | TFIP11 | 0.808525 | 3 | 0 | 3 |
| DDX23 | DUS3L | 0.808341 | 3 | 0 | 3 |
| DDX23 | DOCK6 | 0.776729 | 4 | 0 | 4 |
| DDX23 | RBM15B | 0.758032 | 3 | 0 | 3 |
| DDX23 | NSD1 | 0.757557 | 3 | 0 | 3 |
| DDX23 | ZC3H18 | 0.745784 | 4 | 0 | 4 |
| DDX23 | PIGM | 0.740965 | 3 | 0 | 3 |
| DDX23 | API5 | 0.734814 | 4 | 0 | 4 |
| DDX23 | RBM4B | 0.722418 | 4 | 0 | 3 |
| DDX23 | ZNF564 | 0.719567 | 3 | 0 | 3 |
| DDX23 | KTI12 | 0.718727 | 3 | 0 | 3 |
| DDX23 | MED10 | 0.716907 | 3 | 0 | 3 |
| DDX23 | SPNS1 | 0.716322 | 4 | 0 | 4 |
| DDX23 | ILF3 | 0.711411 | 7 | 0 | 6 |
| DDX23 | ANKRD65 | 0.710641 | 3 | 0 | 3 |
| DDX23 | ATP6AP1 | 0.71057 | 3 | 0 | 3 |
| DDX23 | RPS6KA3 | 0.708675 | 3 | 0 | 3 |
| DDX23 | BOLA1 | 0.705854 | 4 | 0 | 3 |
| DDX23 | ERP27 | 0.703462 | 4 | 0 | 3 |
For details and further investigation, click here
