| Full name: interleukin enhancer binding factor 3 | Alias Symbol: NF90|MPHOSPH4|MPP4|NFAR-1|NFAR110|NFAR-2|TCP110|NF110|DRBP76|NFAR90|NF110b|NF90a|NF90c|NF90ctv|MPP4110 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 3609 | HGNC ID: HGNC:6038 | Ensembl Gene: ENSG00000129351 | OMIM ID: 603182 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ILF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ILF3 | 3609 | 211375_s_at | 0.7142 | 0.1615 | |
| GSE20347 | ILF3 | 3609 | 211375_s_at | 1.0344 | 0.0000 | |
| GSE23400 | ILF3 | 3609 | 211375_s_at | 0.9072 | 0.0000 | |
| GSE26886 | ILF3 | 3609 | 211375_s_at | 0.3883 | 0.0374 | |
| GSE29001 | ILF3 | 3609 | 211375_s_at | 0.8421 | 0.0115 | |
| GSE38129 | ILF3 | 3609 | 211375_s_at | 0.9191 | 0.0000 | |
| GSE45670 | ILF3 | 3609 | 211375_s_at | 0.6339 | 0.0004 | |
| GSE53622 | ILF3 | 3609 | 9731 | 0.4670 | 0.0000 | |
| GSE53624 | ILF3 | 3609 | 9731 | 0.6400 | 0.0000 | |
| GSE63941 | ILF3 | 3609 | 211375_s_at | 0.8660 | 0.0059 | |
| GSE77861 | ILF3 | 3609 | 211375_s_at | 0.9864 | 0.0005 | |
| GSE97050 | ILF3 | 3609 | A_23_P218456 | 0.1983 | 0.3624 | |
| SRP007169 | ILF3 | 3609 | RNAseq | 1.3688 | 0.0002 | |
| SRP008496 | ILF3 | 3609 | RNAseq | 1.2952 | 0.0000 | |
| SRP064894 | ILF3 | 3609 | RNAseq | 0.3852 | 0.0182 | |
| SRP133303 | ILF3 | 3609 | RNAseq | 0.4468 | 0.0047 | |
| SRP159526 | ILF3 | 3609 | RNAseq | 0.4551 | 0.1397 | |
| SRP193095 | ILF3 | 3609 | RNAseq | 0.4576 | 0.0000 | |
| SRP219564 | ILF3 | 3609 | RNAseq | 0.6342 | 0.0955 | |
| TCGA | ILF3 | 3609 | RNAseq | 0.1120 | 0.0044 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ILF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ILF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ILF3 | 3609 | 4 | 3 | 23 | |
| GSE20123 | ILF3 | 3609 | 3 | 1 | 26 | |
| GSE43470 | ILF3 | 3609 | 3 | 6 | 34 | |
| GSE46452 | ILF3 | 3609 | 47 | 1 | 11 | |
| GSE47630 | ILF3 | 3609 | 4 | 7 | 29 | |
| GSE54993 | ILF3 | 3609 | 16 | 3 | 51 | |
| GSE54994 | ILF3 | 3609 | 6 | 13 | 34 | |
| GSE60625 | ILF3 | 3609 | 9 | 0 | 2 | |
| GSE74703 | ILF3 | 3609 | 3 | 4 | 29 | |
| GSE74704 | ILF3 | 3609 | 0 | 1 | 19 | |
| TCGA | ILF3 | 3609 | 15 | 14 | 67 |
Total number of gains: 110; Total number of losses: 53; Total Number of normals: 325.
Somatic mutations of ILF3:
Generating mutation plots.
Highly correlated genes for ILF3:
Showing top 20/1881 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ILF3 | NIPA1 | 0.835913 | 3 | 0 | 3 |
| ILF3 | CEP41 | 0.795042 | 3 | 0 | 3 |
| ILF3 | SCNM1 | 0.781629 | 3 | 0 | 3 |
| ILF3 | DNMT1 | 0.780899 | 12 | 0 | 12 |
| ILF3 | SUPT16H | 0.768385 | 8 | 0 | 7 |
| ILF3 | U2SURP | 0.763824 | 9 | 0 | 9 |
| ILF3 | ELOF1 | 0.761658 | 5 | 0 | 4 |
| ILF3 | VMA21 | 0.759546 | 4 | 0 | 4 |
| ILF3 | CHERP | 0.758701 | 11 | 0 | 10 |
| ILF3 | RNPS1 | 0.753305 | 11 | 0 | 10 |
| ILF3 | NASP | 0.751284 | 9 | 0 | 8 |
| ILF3 | SRRT | 0.748447 | 11 | 0 | 11 |
| ILF3 | LRRC58 | 0.742098 | 5 | 0 | 4 |
| ILF3 | TMEM63B | 0.74115 | 4 | 0 | 4 |
| ILF3 | SIX4 | 0.739992 | 7 | 0 | 7 |
| ILF3 | SPDYE3 | 0.736701 | 3 | 0 | 3 |
| ILF3 | TRMT1 | 0.734233 | 12 | 0 | 12 |
| ILF3 | FXR1 | 0.734037 | 8 | 0 | 8 |
| ILF3 | DYRK2 | 0.733619 | 3 | 0 | 3 |
| ILF3 | FZD6 | 0.732647 | 8 | 0 | 8 |
For details and further investigation, click here
