| Full name: solute carrier family 4 member 5 | Alias Symbol: NBC4 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 57835 | HGNC ID: HGNC:18168 | Ensembl Gene: ENSG00000188687 | OMIM ID: 606757 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC4A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC4A5 | 57835 | 221723_s_at | -0.0158 | 0.9646 | |
| GSE20347 | SLC4A5 | 57835 | 221723_s_at | -0.0066 | 0.9284 | |
| GSE23400 | SLC4A5 | 57835 | 221723_s_at | -0.0219 | 0.4162 | |
| GSE26886 | SLC4A5 | 57835 | 1555277_a_at | 0.1887 | 0.0666 | |
| GSE29001 | SLC4A5 | 57835 | 221723_s_at | -0.1701 | 0.3336 | |
| GSE38129 | SLC4A5 | 57835 | 221723_s_at | -0.1212 | 0.1938 | |
| GSE45670 | SLC4A5 | 57835 | 221723_s_at | 0.0299 | 0.6932 | |
| GSE63941 | SLC4A5 | 57835 | 221723_s_at | 0.4279 | 0.0096 | |
| GSE77861 | SLC4A5 | 57835 | 1555277_a_at | 0.0105 | 0.9345 | |
| GSE97050 | SLC4A5 | 57835 | A_33_P3241388 | -0.2229 | 0.4124 | |
| SRP064894 | SLC4A5 | 57835 | RNAseq | 0.1077 | 0.6623 | |
| SRP133303 | SLC4A5 | 57835 | RNAseq | -0.3916 | 0.0182 | |
| SRP159526 | SLC4A5 | 57835 | RNAseq | 0.5692 | 0.3009 | |
| SRP193095 | SLC4A5 | 57835 | RNAseq | 0.4872 | 0.0115 | |
| SRP219564 | SLC4A5 | 57835 | RNAseq | 0.1183 | 0.7908 | |
| TCGA | SLC4A5 | 57835 | RNAseq | -0.0509 | 0.5770 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC4A5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SLC4A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC4A5 | 57835 | 10 | 1 | 19 | |
| GSE20123 | SLC4A5 | 57835 | 11 | 1 | 18 | |
| GSE43470 | SLC4A5 | 57835 | 4 | 0 | 39 | |
| GSE46452 | SLC4A5 | 57835 | 2 | 3 | 54 | |
| GSE47630 | SLC4A5 | 57835 | 7 | 0 | 33 | |
| GSE54993 | SLC4A5 | 57835 | 0 | 6 | 64 | |
| GSE54994 | SLC4A5 | 57835 | 10 | 0 | 43 | |
| GSE60625 | SLC4A5 | 57835 | 0 | 3 | 8 | |
| GSE74703 | SLC4A5 | 57835 | 4 | 0 | 32 | |
| GSE74704 | SLC4A5 | 57835 | 8 | 0 | 12 | |
| TCGA | SLC4A5 | 57835 | 38 | 2 | 56 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of SLC4A5:
Generating mutation plots.
Highly correlated genes for SLC4A5:
Showing top 20/242 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC4A5 | DDX51 | 0.747352 | 3 | 0 | 3 |
| SLC4A5 | PIGX | 0.73726 | 3 | 0 | 3 |
| SLC4A5 | LRRC55 | 0.729056 | 3 | 0 | 3 |
| SLC4A5 | EHD1 | 0.728079 | 3 | 0 | 3 |
| SLC4A5 | USP19 | 0.715649 | 3 | 0 | 3 |
| SLC4A5 | CSF2RA | 0.714283 | 4 | 0 | 3 |
| SLC4A5 | TEAD4 | 0.707049 | 3 | 0 | 3 |
| SLC4A5 | TMEM214 | 0.705401 | 4 | 0 | 4 |
| SLC4A5 | HDAC11 | 0.704471 | 4 | 0 | 3 |
| SLC4A5 | NPFF | 0.697296 | 4 | 0 | 4 |
| SLC4A5 | SELPLG | 0.687645 | 4 | 0 | 4 |
| SLC4A5 | RFX2 | 0.687231 | 4 | 0 | 3 |
| SLC4A5 | LRRC36 | 0.684212 | 3 | 0 | 3 |
| SLC4A5 | ZNF467 | 0.68402 | 4 | 0 | 4 |
| SLC4A5 | NAPA | 0.680286 | 3 | 0 | 3 |
| SLC4A5 | EDA2R | 0.672433 | 4 | 0 | 3 |
| SLC4A5 | VRK3 | 0.6637 | 4 | 0 | 3 |
| SLC4A5 | GAK | 0.662671 | 3 | 0 | 3 |
| SLC4A5 | RAPGEF1 | 0.658305 | 4 | 0 | 3 |
| SLC4A5 | SCN10A | 0.658208 | 3 | 0 | 3 |
For details and further investigation, click here
