| Full name: ADP ribosylation factor GTPase activating protein 1 | Alias Symbol: FLJ10767|bA261N11.3 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 55738 | HGNC ID: HGNC:15852 | Ensembl Gene: ENSG00000101199 | OMIM ID: 608377 |
| Drug and gene relationship at DGIdb | |||
Expression of ARFGAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARFGAP1 | 55738 | 217888_s_at | 0.9520 | 0.0451 | |
| GSE20347 | ARFGAP1 | 55738 | 217888_s_at | 0.4869 | 0.0001 | |
| GSE23400 | ARFGAP1 | 55738 | 217888_s_at | 0.3649 | 0.0000 | |
| GSE26886 | ARFGAP1 | 55738 | 217888_s_at | 0.4791 | 0.0162 | |
| GSE29001 | ARFGAP1 | 55738 | 217888_s_at | 0.6792 | 0.1408 | |
| GSE38129 | ARFGAP1 | 55738 | 217888_s_at | 0.4281 | 0.0000 | |
| GSE45670 | ARFGAP1 | 55738 | 217888_s_at | 0.5360 | 0.0001 | |
| GSE53622 | ARFGAP1 | 55738 | 135817 | 0.7402 | 0.0000 | |
| GSE53624 | ARFGAP1 | 55738 | 135817 | 0.8315 | 0.0000 | |
| GSE63941 | ARFGAP1 | 55738 | 217888_s_at | -0.6957 | 0.0766 | |
| GSE77861 | ARFGAP1 | 55738 | 217888_s_at | 0.2445 | 0.0387 | |
| GSE97050 | ARFGAP1 | 55738 | A_23_P210379 | 0.3081 | 0.2729 | |
| SRP007169 | ARFGAP1 | 55738 | RNAseq | 0.8173 | 0.0370 | |
| SRP008496 | ARFGAP1 | 55738 | RNAseq | 1.0154 | 0.0006 | |
| SRP064894 | ARFGAP1 | 55738 | RNAseq | 1.3020 | 0.0000 | |
| SRP133303 | ARFGAP1 | 55738 | RNAseq | 0.8107 | 0.0000 | |
| SRP159526 | ARFGAP1 | 55738 | RNAseq | 0.8688 | 0.0585 | |
| SRP193095 | ARFGAP1 | 55738 | RNAseq | 0.6905 | 0.0000 | |
| SRP219564 | ARFGAP1 | 55738 | RNAseq | 1.0163 | 0.0023 | |
| TCGA | ARFGAP1 | 55738 | RNAseq | 0.0278 | 0.5628 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ARFGAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARFGAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARFGAP1 | 55738 | 14 | 2 | 14 | |
| GSE20123 | ARFGAP1 | 55738 | 14 | 2 | 14 | |
| GSE43470 | ARFGAP1 | 55738 | 11 | 1 | 31 | |
| GSE46452 | ARFGAP1 | 55738 | 35 | 0 | 24 | |
| GSE47630 | ARFGAP1 | 55738 | 25 | 1 | 14 | |
| GSE54993 | ARFGAP1 | 55738 | 0 | 17 | 53 | |
| GSE54994 | ARFGAP1 | 55738 | 29 | 0 | 24 | |
| GSE60625 | ARFGAP1 | 55738 | 0 | 0 | 11 | |
| GSE74703 | ARFGAP1 | 55738 | 10 | 0 | 26 | |
| GSE74704 | ARFGAP1 | 55738 | 11 | 0 | 9 | |
| TCGA | ARFGAP1 | 55738 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 27; Total Number of normals: 268.
Somatic mutations of ARFGAP1:
Generating mutation plots.
Highly correlated genes for ARFGAP1:
Showing top 20/1000 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARFGAP1 | SLC19A1 | 0.738185 | 3 | 0 | 3 |
| ARFGAP1 | KCNS2 | 0.719099 | 3 | 0 | 3 |
| ARFGAP1 | CABLES2 | 0.702698 | 3 | 0 | 3 |
| ARFGAP1 | UTP23 | 0.686914 | 5 | 0 | 5 |
| ARFGAP1 | DDX51 | 0.685198 | 3 | 0 | 3 |
| ARFGAP1 | SH3BP2 | 0.680319 | 3 | 0 | 3 |
| ARFGAP1 | FUCA2 | 0.677178 | 5 | 0 | 4 |
| ARFGAP1 | DDX55 | 0.676634 | 6 | 0 | 6 |
| ARFGAP1 | AGRN | 0.671716 | 12 | 0 | 12 |
| ARFGAP1 | NSMF | 0.671084 | 3 | 0 | 3 |
| ARFGAP1 | UBE2J2 | 0.668868 | 3 | 0 | 3 |
| ARFGAP1 | INTS1 | 0.66101 | 10 | 0 | 8 |
| ARFGAP1 | ZNF335 | 0.659486 | 9 | 0 | 8 |
| ARFGAP1 | ADRM1 | 0.658998 | 10 | 0 | 9 |
| ARFGAP1 | MAF1 | 0.657084 | 4 | 0 | 4 |
| ARFGAP1 | COL27A1 | 0.656852 | 6 | 0 | 5 |
| ARFGAP1 | SDK1 | 0.656117 | 3 | 0 | 3 |
| ARFGAP1 | KPNA1 | 0.655389 | 3 | 0 | 3 |
| ARFGAP1 | C4orf48 | 0.654686 | 8 | 0 | 7 |
| ARFGAP1 | B4GALT7 | 0.653196 | 10 | 0 | 9 |
For details and further investigation, click here
