| Full name: solute carrier family 6 member 9 | Alias Symbol: GLYT1 | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 6536 | HGNC ID: HGNC:11056 | Ensembl Gene: ENSG00000196517 | OMIM ID: 601019 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A9 | 6536 | 207043_s_at | -0.1569 | 0.7963 | |
| GSE20347 | SLC6A9 | 6536 | 207043_s_at | -0.0883 | 0.1704 | |
| GSE23400 | SLC6A9 | 6536 | 207043_s_at | -0.0706 | 0.1247 | |
| GSE26886 | SLC6A9 | 6536 | 207043_s_at | 0.1905 | 0.1957 | |
| GSE29001 | SLC6A9 | 6536 | 207043_s_at | -0.1144 | 0.4116 | |
| GSE38129 | SLC6A9 | 6536 | 207043_s_at | -0.1465 | 0.0398 | |
| GSE45670 | SLC6A9 | 6536 | 207043_s_at | 0.0263 | 0.7650 | |
| GSE53622 | SLC6A9 | 6536 | 38557 | -0.4703 | 0.0000 | |
| GSE53624 | SLC6A9 | 6536 | 172856 | -0.4783 | 0.0000 | |
| GSE63941 | SLC6A9 | 6536 | 207043_s_at | 1.3263 | 0.0339 | |
| GSE77861 | SLC6A9 | 6536 | 207043_s_at | -0.1851 | 0.2118 | |
| GSE97050 | SLC6A9 | 6536 | A_23_P11984 | 0.0954 | 0.8260 | |
| SRP007169 | SLC6A9 | 6536 | RNAseq | -1.6786 | 0.0135 | |
| SRP008496 | SLC6A9 | 6536 | RNAseq | -1.9269 | 0.0000 | |
| SRP064894 | SLC6A9 | 6536 | RNAseq | -0.1822 | 0.4983 | |
| SRP133303 | SLC6A9 | 6536 | RNAseq | -0.5778 | 0.1173 | |
| SRP159526 | SLC6A9 | 6536 | RNAseq | -0.0632 | 0.8398 | |
| SRP193095 | SLC6A9 | 6536 | RNAseq | 0.0236 | 0.9193 | |
| SRP219564 | SLC6A9 | 6536 | RNAseq | -0.4579 | 0.3671 | |
| TCGA | SLC6A9 | 6536 | RNAseq | 0.1206 | 0.2036 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by SLC6A9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A9 | 6536 | 4 | 3 | 23 | |
| GSE20123 | SLC6A9 | 6536 | 4 | 2 | 24 | |
| GSE43470 | SLC6A9 | 6536 | 7 | 2 | 34 | |
| GSE46452 | SLC6A9 | 6536 | 2 | 1 | 56 | |
| GSE47630 | SLC6A9 | 6536 | 9 | 3 | 28 | |
| GSE54993 | SLC6A9 | 6536 | 0 | 2 | 68 | |
| GSE54994 | SLC6A9 | 6536 | 14 | 2 | 37 | |
| GSE60625 | SLC6A9 | 6536 | 0 | 0 | 11 | |
| GSE74703 | SLC6A9 | 6536 | 6 | 1 | 29 | |
| GSE74704 | SLC6A9 | 6536 | 2 | 0 | 18 | |
| TCGA | SLC6A9 | 6536 | 14 | 16 | 66 |
Total number of gains: 62; Total number of losses: 32; Total Number of normals: 394.
Somatic mutations of SLC6A9:
Generating mutation plots.
Highly correlated genes for SLC6A9:
Showing top 20/351 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A9 | SLC1A5 | 0.781799 | 3 | 0 | 3 |
| SLC6A9 | RAP2A | 0.740623 | 3 | 0 | 3 |
| SLC6A9 | GBF1 | 0.733431 | 3 | 0 | 3 |
| SLC6A9 | DNHD1 | 0.719649 | 3 | 0 | 3 |
| SLC6A9 | RBP2 | 0.708032 | 3 | 0 | 3 |
| SLC6A9 | XRRA1 | 0.700873 | 4 | 0 | 3 |
| SLC6A9 | BCL9L | 0.700714 | 3 | 0 | 3 |
| SLC6A9 | RNASEH2B | 0.691258 | 3 | 0 | 3 |
| SLC6A9 | REPS1 | 0.688028 | 3 | 0 | 3 |
| SLC6A9 | STRN4 | 0.687875 | 4 | 0 | 4 |
| SLC6A9 | MYO3B | 0.687276 | 3 | 0 | 3 |
| SLC6A9 | BARHL1 | 0.682756 | 3 | 0 | 3 |
| SLC6A9 | DNAH11 | 0.682403 | 3 | 0 | 3 |
| SLC6A9 | DERL3 | 0.681962 | 3 | 0 | 3 |
| SLC6A9 | DDX51 | 0.680125 | 3 | 0 | 3 |
| SLC6A9 | TBC1D22A | 0.679237 | 4 | 0 | 3 |
| SLC6A9 | AKAP7 | 0.676924 | 3 | 0 | 3 |
| SLC6A9 | ZNF814 | 0.675618 | 3 | 0 | 3 |
| SLC6A9 | NDUFV1 | 0.670916 | 3 | 0 | 3 |
| SLC6A9 | TAS2R4 | 0.669897 | 3 | 0 | 3 |
For details and further investigation, click here
