| Full name: autophagy related 2A | Alias Symbol: KIAA0404 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 23130 | HGNC ID: HGNC:29028 | Ensembl Gene: ENSG00000110046 | OMIM ID: 616225 |
| Drug and gene relationship at DGIdb | |||
Expression of ATG2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG2A | 23130 | 213300_at | 0.5670 | 0.0438 | |
| GSE20347 | ATG2A | 23130 | 213300_at | 0.1623 | 0.2180 | |
| GSE23400 | ATG2A | 23130 | 213300_at | 0.1993 | 0.0000 | |
| GSE26886 | ATG2A | 23130 | 213300_at | 0.8395 | 0.0000 | |
| GSE29001 | ATG2A | 23130 | 213300_at | 0.0621 | 0.8706 | |
| GSE38129 | ATG2A | 23130 | 213300_at | 0.0872 | 0.3517 | |
| GSE45670 | ATG2A | 23130 | 213300_at | 0.3171 | 0.0208 | |
| GSE53622 | ATG2A | 23130 | 46107 | -0.0226 | 0.7526 | |
| GSE53624 | ATG2A | 23130 | 46107 | 0.2725 | 0.0000 | |
| GSE63941 | ATG2A | 23130 | 213300_at | -0.3153 | 0.4240 | |
| GSE77861 | ATG2A | 23130 | 213300_at | 0.1140 | 0.2738 | |
| GSE97050 | ATG2A | 23130 | A_33_P3257312 | 0.1506 | 0.5256 | |
| SRP007169 | ATG2A | 23130 | RNAseq | 0.1116 | 0.8264 | |
| SRP008496 | ATG2A | 23130 | RNAseq | 0.1445 | 0.6120 | |
| SRP064894 | ATG2A | 23130 | RNAseq | 0.2417 | 0.1205 | |
| SRP133303 | ATG2A | 23130 | RNAseq | 0.2631 | 0.1179 | |
| SRP159526 | ATG2A | 23130 | RNAseq | 0.3278 | 0.2048 | |
| SRP193095 | ATG2A | 23130 | RNAseq | 0.6472 | 0.0000 | |
| SRP219564 | ATG2A | 23130 | RNAseq | -0.0400 | 0.9062 | |
| TCGA | ATG2A | 23130 | RNAseq | -0.0818 | 0.0798 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATG2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATG2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG2A | 23130 | 7 | 6 | 17 | |
| GSE20123 | ATG2A | 23130 | 7 | 6 | 17 | |
| GSE43470 | ATG2A | 23130 | 1 | 3 | 39 | |
| GSE46452 | ATG2A | 23130 | 10 | 4 | 45 | |
| GSE47630 | ATG2A | 23130 | 5 | 6 | 29 | |
| GSE54993 | ATG2A | 23130 | 3 | 0 | 67 | |
| GSE54994 | ATG2A | 23130 | 6 | 5 | 42 | |
| GSE60625 | ATG2A | 23130 | 0 | 3 | 8 | |
| GSE74703 | ATG2A | 23130 | 1 | 1 | 34 | |
| GSE74704 | ATG2A | 23130 | 5 | 4 | 11 | |
| TCGA | ATG2A | 23130 | 23 | 7 | 66 |
Total number of gains: 68; Total number of losses: 45; Total Number of normals: 375.
Somatic mutations of ATG2A:
Generating mutation plots.
Highly correlated genes for ATG2A:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG2A | SERPINF2 | 0.747922 | 3 | 0 | 3 |
| ATG2A | HOXC13 | 0.730038 | 3 | 0 | 3 |
| ATG2A | ADAM15 | 0.723319 | 3 | 0 | 3 |
| ATG2A | DCUN1D5 | 0.717512 | 3 | 0 | 3 |
| ATG2A | NTPCR | 0.708812 | 3 | 0 | 3 |
| ATG2A | KIF21B | 0.691464 | 3 | 0 | 3 |
| ATG2A | RAB15 | 0.691261 | 4 | 0 | 3 |
| ATG2A | STIM2 | 0.682932 | 3 | 0 | 3 |
| ATG2A | SLC45A3 | 0.681577 | 3 | 0 | 3 |
| ATG2A | ABCC10 | 0.677925 | 4 | 0 | 3 |
| ATG2A | INO80B | 0.673116 | 3 | 0 | 3 |
| ATG2A | UCN2 | 0.672163 | 4 | 0 | 4 |
| ATG2A | DNAJC30 | 0.668902 | 6 | 0 | 5 |
| ATG2A | CTU2 | 0.667748 | 4 | 0 | 4 |
| ATG2A | SHANK1 | 0.66758 | 3 | 0 | 3 |
| ATG2A | ATP11A | 0.665147 | 3 | 0 | 3 |
| ATG2A | GEMIN4 | 0.66439 | 3 | 0 | 3 |
| ATG2A | CASP6 | 0.656984 | 4 | 0 | 4 |
| ATG2A | ZNF362 | 0.65587 | 3 | 0 | 3 |
| ATG2A | TMEM104 | 0.653456 | 4 | 0 | 3 |
For details and further investigation, click here
