| Full name: cytotoxic and regulatory T cell molecule | Alias Symbol: CD355 | ||
| Type: protein-coding gene | Cytoband: 11q24.1 | ||
| Entrez ID: 56253 | HGNC ID: HGNC:24313 | Ensembl Gene: ENSG00000109943 | OMIM ID: 612597 |
| Drug and gene relationship at DGIdb | |||
Expression of CRTAM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRTAM | 56253 | 206914_at | 0.4021 | 0.6794 | |
| GSE20347 | CRTAM | 56253 | 206914_at | -0.1196 | 0.3155 | |
| GSE23400 | CRTAM | 56253 | 206914_at | -0.0316 | 0.1173 | |
| GSE26886 | CRTAM | 56253 | 206914_at | -0.2130 | 0.3393 | |
| GSE29001 | CRTAM | 56253 | 206914_at | 0.1289 | 0.6770 | |
| GSE38129 | CRTAM | 56253 | 206914_at | -0.1193 | 0.3460 | |
| GSE45670 | CRTAM | 56253 | 206914_at | -0.3090 | 0.1445 | |
| GSE63941 | CRTAM | 56253 | 206914_at | -0.0673 | 0.6115 | |
| GSE77861 | CRTAM | 56253 | 206914_at | 0.0423 | 0.6203 | |
| SRP133303 | CRTAM | 56253 | RNAseq | -0.4127 | 0.0538 | |
| SRP193095 | CRTAM | 56253 | RNAseq | -0.2049 | 0.2459 | |
| SRP219564 | CRTAM | 56253 | RNAseq | 0.5900 | 0.2943 | |
| TCGA | CRTAM | 56253 | RNAseq | 0.5231 | 0.2667 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRTAM expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CRTAM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRTAM | 56253 | 0 | 13 | 17 | |
| GSE20123 | CRTAM | 56253 | 0 | 13 | 17 | |
| GSE43470 | CRTAM | 56253 | 2 | 7 | 34 | |
| GSE46452 | CRTAM | 56253 | 3 | 26 | 30 | |
| GSE47630 | CRTAM | 56253 | 2 | 19 | 19 | |
| GSE54993 | CRTAM | 56253 | 10 | 0 | 60 | |
| GSE54994 | CRTAM | 56253 | 5 | 19 | 29 | |
| GSE60625 | CRTAM | 56253 | 0 | 3 | 8 | |
| GSE74703 | CRTAM | 56253 | 1 | 5 | 30 | |
| GSE74704 | CRTAM | 56253 | 0 | 9 | 11 | |
| TCGA | CRTAM | 56253 | 5 | 50 | 41 |
Total number of gains: 28; Total number of losses: 164; Total Number of normals: 296.
Somatic mutations of CRTAM:
Generating mutation plots.
Highly correlated genes for CRTAM:
Showing top 20/87 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRTAM | LAPTM5 | 0.68317 | 4 | 0 | 4 |
| CRTAM | CD37 | 0.671218 | 3 | 0 | 3 |
| CRTAM | NKG7 | 0.668963 | 6 | 0 | 5 |
| CRTAM | HLA-DPB1 | 0.66789 | 4 | 0 | 4 |
| CRTAM | CCL5 | 0.664381 | 5 | 0 | 4 |
| CRTAM | GZMA | 0.663685 | 5 | 0 | 5 |
| CRTAM | IL2RG | 0.662884 | 3 | 0 | 3 |
| CRTAM | CD96 | 0.659746 | 5 | 0 | 5 |
| CRTAM | IL2RB | 0.653326 | 5 | 0 | 5 |
| CRTAM | CD84 | 0.650907 | 6 | 0 | 6 |
| CRTAM | AKAP5 | 0.647806 | 4 | 0 | 3 |
| CRTAM | KLRD1 | 0.645523 | 4 | 0 | 3 |
| CRTAM | CD52 | 0.638058 | 4 | 0 | 4 |
| CRTAM | CD53 | 0.633291 | 5 | 0 | 5 |
| CRTAM | CD8A | 0.630134 | 6 | 0 | 4 |
| CRTAM | CYTIP | 0.622136 | 6 | 0 | 4 |
| CRTAM | EVI2B | 0.619524 | 6 | 0 | 5 |
| CRTAM | CD247 | 0.616483 | 6 | 0 | 5 |
| CRTAM | CCR5 | 0.612849 | 6 | 0 | 4 |
| CRTAM | STAT4 | 0.606302 | 5 | 0 | 3 |
For details and further investigation, click here
