| Full name: coiled-coil-helix-coiled-coil-helix domain containing 7 | Alias Symbol: MGC2217|COX23 | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 79145 | HGNC ID: HGNC:28314 | Ensembl Gene: ENSG00000170791 | OMIM ID: 611238 |
| Drug and gene relationship at DGIdb | |||
Expression of CHCHD7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHCHD7 | 79145 | 222701_s_at | 0.7205 | 0.4035 | |
| GSE20347 | CHCHD7 | 79145 | 218642_s_at | 0.5714 | 0.0116 | |
| GSE23400 | CHCHD7 | 79145 | 218642_s_at | 0.3146 | 0.0003 | |
| GSE26886 | CHCHD7 | 79145 | 218642_s_at | 0.6562 | 0.0119 | |
| GSE29001 | CHCHD7 | 79145 | 218642_s_at | 0.6294 | 0.0169 | |
| GSE38129 | CHCHD7 | 79145 | 218642_s_at | 0.1649 | 0.4039 | |
| GSE45670 | CHCHD7 | 79145 | 222701_s_at | 0.7714 | 0.0016 | |
| GSE53622 | CHCHD7 | 79145 | 21223 | -0.1627 | 0.1163 | |
| GSE53624 | CHCHD7 | 79145 | 21223 | 0.2924 | 0.0004 | |
| GSE63941 | CHCHD7 | 79145 | 222701_s_at | 1.4090 | 0.0315 | |
| GSE77861 | CHCHD7 | 79145 | 222701_s_at | 0.2110 | 0.5971 | |
| GSE97050 | CHCHD7 | 79145 | A_23_P170626 | -0.3086 | 0.2946 | |
| SRP007169 | CHCHD7 | 79145 | RNAseq | 1.1339 | 0.0751 | |
| SRP008496 | CHCHD7 | 79145 | RNAseq | 1.8148 | 0.0011 | |
| SRP064894 | CHCHD7 | 79145 | RNAseq | 0.1576 | 0.3390 | |
| SRP133303 | CHCHD7 | 79145 | RNAseq | 0.4778 | 0.0170 | |
| SRP159526 | CHCHD7 | 79145 | RNAseq | 0.4843 | 0.0297 | |
| SRP193095 | CHCHD7 | 79145 | RNAseq | -0.0755 | 0.6413 | |
| SRP219564 | CHCHD7 | 79145 | RNAseq | 0.4836 | 0.1591 | |
| TCGA | CHCHD7 | 79145 | RNAseq | -0.1332 | 0.0631 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CHCHD7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHCHD7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHCHD7 | 79145 | 14 | 1 | 15 | |
| GSE20123 | CHCHD7 | 79145 | 14 | 1 | 15 | |
| GSE43470 | CHCHD7 | 79145 | 13 | 3 | 27 | |
| GSE46452 | CHCHD7 | 79145 | 20 | 3 | 36 | |
| GSE47630 | CHCHD7 | 79145 | 23 | 1 | 16 | |
| GSE54993 | CHCHD7 | 79145 | 1 | 17 | 52 | |
| GSE54994 | CHCHD7 | 79145 | 28 | 0 | 25 | |
| GSE60625 | CHCHD7 | 79145 | 0 | 4 | 7 | |
| GSE74703 | CHCHD7 | 79145 | 12 | 2 | 22 | |
| GSE74704 | CHCHD7 | 79145 | 10 | 0 | 10 | |
| TCGA | CHCHD7 | 79145 | 43 | 8 | 45 |
Total number of gains: 178; Total number of losses: 40; Total Number of normals: 270.
Somatic mutations of CHCHD7:
Generating mutation plots.
Highly correlated genes for CHCHD7:
Showing top 20/765 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHCHD7 | ACSL1 | 0.823465 | 3 | 0 | 3 |
| CHCHD7 | ABCD4 | 0.778076 | 3 | 0 | 3 |
| CHCHD7 | CORO1C | 0.774544 | 3 | 0 | 3 |
| CHCHD7 | ZFYVE26 | 0.770045 | 3 | 0 | 3 |
| CHCHD7 | PSMB6 | 0.753953 | 3 | 0 | 3 |
| CHCHD7 | ZNF550 | 0.74831 | 3 | 0 | 3 |
| CHCHD7 | BRD2 | 0.739416 | 3 | 0 | 3 |
| CHCHD7 | DCP2 | 0.739306 | 3 | 0 | 3 |
| CHCHD7 | DGKH | 0.73803 | 3 | 0 | 3 |
| CHCHD7 | ACBD6 | 0.715566 | 3 | 0 | 3 |
| CHCHD7 | HNRNPUL1 | 0.714159 | 4 | 0 | 4 |
| CHCHD7 | ARHGAP18 | 0.713893 | 3 | 0 | 3 |
| CHCHD7 | BRD9 | 0.713719 | 3 | 0 | 3 |
| CHCHD7 | WDR75 | 0.712135 | 3 | 0 | 3 |
| CHCHD7 | NEK7 | 0.708214 | 4 | 0 | 4 |
| CHCHD7 | CHD1 | 0.706546 | 3 | 0 | 3 |
| CHCHD7 | LDB1 | 0.703361 | 4 | 0 | 4 |
| CHCHD7 | RNMT | 0.702657 | 3 | 0 | 3 |
| CHCHD7 | POMP | 0.702107 | 3 | 0 | 3 |
| CHCHD7 | RP9 | 0.699823 | 4 | 0 | 3 |
For details and further investigation, click here
