| Full name: glucoside xylosyltransferase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p13 | ||
| Entrez ID: 727936 | HGNC ID: HGNC:33383 | Ensembl Gene: ENSG00000172986 | OMIM ID: 613322 |
| Drug and gene relationship at DGIdb | |||
Expression of GXYLT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GXYLT2 | 727936 | 235371_at | 1.2473 | 0.1802 | |
| GSE26886 | GXYLT2 | 727936 | 235733_at | 1.3974 | 0.0004 | |
| GSE45670 | GXYLT2 | 727936 | 235371_at | -0.1986 | 0.6377 | |
| GSE53622 | GXYLT2 | 727936 | 11299 | 1.3553 | 0.0000 | |
| GSE53624 | GXYLT2 | 727936 | 11299 | 1.5656 | 0.0000 | |
| GSE63941 | GXYLT2 | 727936 | 235371_at | -2.5038 | 0.0190 | |
| GSE77861 | GXYLT2 | 727936 | 235733_at | 0.3950 | 0.2562 | |
| GSE97050 | GXYLT2 | 727936 | A_24_P118196 | 0.7968 | 0.1420 | |
| SRP007169 | GXYLT2 | 727936 | RNAseq | 3.5905 | 0.0000 | |
| SRP008496 | GXYLT2 | 727936 | RNAseq | 3.6231 | 0.0000 | |
| SRP064894 | GXYLT2 | 727936 | RNAseq | 1.6262 | 0.0001 | |
| SRP133303 | GXYLT2 | 727936 | RNAseq | 1.4849 | 0.0000 | |
| SRP159526 | GXYLT2 | 727936 | RNAseq | 2.2668 | 0.0028 | |
| SRP193095 | GXYLT2 | 727936 | RNAseq | 1.5824 | 0.0000 | |
| SRP219564 | GXYLT2 | 727936 | RNAseq | 1.7709 | 0.0066 | |
| TCGA | GXYLT2 | 727936 | RNAseq | 0.0447 | 0.8307 |
Upregulated datasets: 10; Downregulated datasets: 1.
Survival by GXYLT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GXYLT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GXYLT2 | 727936 | 1 | 21 | 8 | |
| GSE20123 | GXYLT2 | 727936 | 1 | 21 | 8 | |
| GSE43470 | GXYLT2 | 727936 | 0 | 21 | 22 | |
| GSE46452 | GXYLT2 | 727936 | 2 | 17 | 40 | |
| GSE47630 | GXYLT2 | 727936 | 1 | 23 | 16 | |
| GSE54993 | GXYLT2 | 727936 | 4 | 3 | 63 | |
| GSE54994 | GXYLT2 | 727936 | 1 | 31 | 21 | |
| GSE60625 | GXYLT2 | 727936 | 3 | 1 | 7 | |
| GSE74703 | GXYLT2 | 727936 | 0 | 17 | 19 | |
| GSE74704 | GXYLT2 | 727936 | 1 | 13 | 6 | |
| TCGA | GXYLT2 | 727936 | 1 | 79 | 16 |
Total number of gains: 15; Total number of losses: 247; Total Number of normals: 226.
Somatic mutations of GXYLT2:
Generating mutation plots.
Highly correlated genes for GXYLT2:
Showing top 20/1045 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GXYLT2 | RAB34 | 0.774179 | 3 | 0 | 3 |
| GXYLT2 | APOLD1 | 0.764757 | 3 | 0 | 3 |
| GXYLT2 | FARP1 | 0.74886 | 5 | 0 | 5 |
| GXYLT2 | CAPN12 | 0.739737 | 3 | 0 | 3 |
| GXYLT2 | LAMB1 | 0.736743 | 7 | 0 | 7 |
| GXYLT2 | AP3B2 | 0.735494 | 3 | 0 | 3 |
| GXYLT2 | IFITM1 | 0.733798 | 4 | 0 | 4 |
| GXYLT2 | SYNPO | 0.733443 | 4 | 0 | 4 |
| GXYLT2 | SPON2 | 0.732826 | 3 | 0 | 3 |
| GXYLT2 | GRINA | 0.731288 | 3 | 0 | 3 |
| GXYLT2 | VKORC1 | 0.73123 | 5 | 0 | 5 |
| GXYLT2 | NCKIPSD | 0.730652 | 3 | 0 | 3 |
| GXYLT2 | LAPTM4B | 0.729395 | 5 | 0 | 5 |
| GXYLT2 | TNS3 | 0.721014 | 7 | 0 | 6 |
| GXYLT2 | GPX8 | 0.720891 | 7 | 0 | 6 |
| GXYLT2 | CEP250 | 0.719824 | 4 | 0 | 4 |
| GXYLT2 | NEK6 | 0.719778 | 6 | 0 | 6 |
| GXYLT2 | DZIP1 | 0.718237 | 7 | 0 | 7 |
| GXYLT2 | GPR137B | 0.717401 | 5 | 0 | 5 |
| GXYLT2 | CDH11 | 0.71482 | 6 | 0 | 6 |
For details and further investigation, click here
