| Full name: DEP domain containing 4 | Alias Symbol: DEP.4|FLJ33505 | ||
| Type: protein-coding gene | Cytoband: 12q23.1 | ||
| Entrez ID: 120863 | HGNC ID: HGNC:22952 | Ensembl Gene: ENSG00000166153 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DEPDC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DEPDC4 | 120863 | 1553365_at | 0.0698 | 0.8426 | |
| GSE26886 | DEPDC4 | 120863 | 1553365_at | -0.0781 | 0.4886 | |
| GSE45670 | DEPDC4 | 120863 | 1553365_at | 0.0660 | 0.6076 | |
| GSE53622 | DEPDC4 | 120863 | 7127 | 0.5390 | 0.0000 | |
| GSE53624 | DEPDC4 | 120863 | 7127 | 0.6794 | 0.0000 | |
| GSE63941 | DEPDC4 | 120863 | 1561114_a_at | 0.5412 | 0.0842 | |
| GSE77861 | DEPDC4 | 120863 | 1553365_at | -0.1385 | 0.3078 | |
| GSE97050 | DEPDC4 | 120863 | A_32_P137966 | 0.1885 | 0.3431 | |
| SRP007169 | DEPDC4 | 120863 | RNAseq | 0.7735 | 0.2553 | |
| SRP064894 | DEPDC4 | 120863 | RNAseq | 0.2845 | 0.1515 | |
| SRP133303 | DEPDC4 | 120863 | RNAseq | 0.1675 | 0.3798 | |
| SRP159526 | DEPDC4 | 120863 | RNAseq | 0.6260 | 0.1712 | |
| SRP193095 | DEPDC4 | 120863 | RNAseq | 0.1974 | 0.0914 | |
| SRP219564 | DEPDC4 | 120863 | RNAseq | 0.1147 | 0.7357 | |
| TCGA | DEPDC4 | 120863 | RNAseq | 0.0786 | 0.7580 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DEPDC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DEPDC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DEPDC4 | 120863 | 2 | 2 | 26 | |
| GSE20123 | DEPDC4 | 120863 | 2 | 2 | 26 | |
| GSE43470 | DEPDC4 | 120863 | 2 | 0 | 41 | |
| GSE46452 | DEPDC4 | 120863 | 9 | 1 | 49 | |
| GSE47630 | DEPDC4 | 120863 | 9 | 1 | 30 | |
| GSE54993 | DEPDC4 | 120863 | 0 | 5 | 65 | |
| GSE54994 | DEPDC4 | 120863 | 4 | 2 | 47 | |
| GSE60625 | DEPDC4 | 120863 | 0 | 0 | 11 | |
| GSE74703 | DEPDC4 | 120863 | 2 | 0 | 34 | |
| GSE74704 | DEPDC4 | 120863 | 1 | 2 | 17 | |
| TCGA | DEPDC4 | 120863 | 18 | 11 | 67 |
Total number of gains: 49; Total number of losses: 26; Total Number of normals: 413.
Somatic mutations of DEPDC4:
Generating mutation plots.
Highly correlated genes for DEPDC4:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DEPDC4 | FANCM | 0.750547 | 3 | 0 | 3 |
| DEPDC4 | BICD2 | 0.74696 | 3 | 0 | 3 |
| DEPDC4 | SLC15A2 | 0.745586 | 3 | 0 | 3 |
| DEPDC4 | LPCAT2 | 0.706924 | 3 | 0 | 3 |
| DEPDC4 | PPP1R3D | 0.688506 | 3 | 0 | 3 |
| DEPDC4 | S1PR5 | 0.685051 | 3 | 0 | 3 |
| DEPDC4 | ANAPC1 | 0.676912 | 3 | 0 | 3 |
| DEPDC4 | TMEM97 | 0.672028 | 3 | 0 | 3 |
| DEPDC4 | RTN4R | 0.660733 | 3 | 0 | 3 |
| DEPDC4 | ZFYVE16 | 0.660113 | 3 | 0 | 3 |
| DEPDC4 | WNT10A | 0.659536 | 3 | 0 | 3 |
| DEPDC4 | STARD7-AS1 | 0.655828 | 3 | 0 | 3 |
| DEPDC4 | C19orf54 | 0.654215 | 3 | 0 | 3 |
| DEPDC4 | STAR | 0.654027 | 3 | 0 | 3 |
| DEPDC4 | REPS1 | 0.652632 | 3 | 0 | 3 |
| DEPDC4 | PYGL | 0.649253 | 3 | 0 | 3 |
| DEPDC4 | CDK18 | 0.648091 | 3 | 0 | 3 |
| DEPDC4 | ZNF785 | 0.646981 | 3 | 0 | 3 |
| DEPDC4 | LRRC28 | 0.644948 | 3 | 0 | 3 |
| DEPDC4 | B3GNT5 | 0.64255 | 3 | 0 | 3 |
For details and further investigation, click here
