| Full name: transmembrane protein 97 | Alias Symbol: MAC30 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 27346 | HGNC ID: HGNC:28106 | Ensembl Gene: ENSG00000109084 | OMIM ID: 612912 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM97:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM97 | 27346 | 212282_at | 1.6993 | 0.0355 | |
| GSE20347 | TMEM97 | 27346 | 212279_at | 1.3617 | 0.0000 | |
| GSE23400 | TMEM97 | 27346 | 212282_at | 1.1267 | 0.0000 | |
| GSE26886 | TMEM97 | 27346 | 212281_s_at | 2.2217 | 0.0000 | |
| GSE29001 | TMEM97 | 27346 | 212281_s_at | 1.2921 | 0.0027 | |
| GSE38129 | TMEM97 | 27346 | 212282_at | 1.6030 | 0.0000 | |
| GSE45670 | TMEM97 | 27346 | 212282_at | 0.9848 | 0.0210 | |
| GSE53622 | TMEM97 | 27346 | 2416 | 1.1958 | 0.0000 | |
| GSE53624 | TMEM97 | 27346 | 2416 | 1.4922 | 0.0000 | |
| GSE63941 | TMEM97 | 27346 | 212282_at | 1.8808 | 0.0058 | |
| GSE77861 | TMEM97 | 27346 | 212279_at | 1.6104 | 0.0034 | |
| GSE97050 | TMEM97 | 27346 | A_24_P190168 | 0.4159 | 0.2586 | |
| SRP007169 | TMEM97 | 27346 | RNAseq | 1.8312 | 0.0001 | |
| SRP008496 | TMEM97 | 27346 | RNAseq | 1.5186 | 0.0000 | |
| SRP064894 | TMEM97 | 27346 | RNAseq | 1.0318 | 0.0000 | |
| SRP133303 | TMEM97 | 27346 | RNAseq | 1.2181 | 0.0001 | |
| SRP159526 | TMEM97 | 27346 | RNAseq | 1.6090 | 0.0000 | |
| SRP193095 | TMEM97 | 27346 | RNAseq | 0.7092 | 0.0103 | |
| SRP219564 | TMEM97 | 27346 | RNAseq | 0.5550 | 0.2302 | |
| TCGA | TMEM97 | 27346 | RNAseq | -0.1661 | 0.0854 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by TMEM97 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM97:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM97 | 27346 | 9 | 1 | 20 | |
| GSE20123 | TMEM97 | 27346 | 9 | 1 | 20 | |
| GSE43470 | TMEM97 | 27346 | 0 | 1 | 42 | |
| GSE46452 | TMEM97 | 27346 | 33 | 1 | 25 | |
| GSE47630 | TMEM97 | 27346 | 7 | 1 | 32 | |
| GSE54993 | TMEM97 | 27346 | 2 | 3 | 65 | |
| GSE54994 | TMEM97 | 27346 | 7 | 6 | 40 | |
| GSE60625 | TMEM97 | 27346 | 4 | 0 | 7 | |
| GSE74703 | TMEM97 | 27346 | 0 | 1 | 35 | |
| GSE74704 | TMEM97 | 27346 | 7 | 1 | 12 | |
| TCGA | TMEM97 | 27346 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of TMEM97:
Generating mutation plots.
Highly correlated genes for TMEM97:
Showing top 20/2125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM97 | DNAJC2 | 0.773452 | 11 | 0 | 11 |
| TMEM97 | EXOC8 | 0.76859 | 3 | 0 | 3 |
| TMEM97 | FLVCR1 | 0.767937 | 8 | 0 | 7 |
| TMEM97 | MCM6 | 0.764438 | 13 | 0 | 12 |
| TMEM97 | HAS3 | 0.764243 | 3 | 0 | 3 |
| TMEM97 | DHX33 | 0.763127 | 7 | 0 | 7 |
| TMEM97 | SLC35B2 | 0.762399 | 3 | 0 | 3 |
| TMEM97 | SLC39A3 | 0.757188 | 4 | 0 | 4 |
| TMEM97 | MIER2 | 0.755048 | 3 | 0 | 3 |
| TMEM97 | SPAG5 | 0.754114 | 13 | 0 | 13 |
| TMEM97 | DTL | 0.745489 | 13 | 0 | 12 |
| TMEM97 | GMNN | 0.745315 | 13 | 0 | 12 |
| TMEM97 | MCM3 | 0.740947 | 12 | 0 | 11 |
| TMEM97 | RAD51AP1 | 0.738241 | 12 | 0 | 12 |
| TMEM97 | DNMT1 | 0.737577 | 13 | 0 | 12 |
| TMEM97 | SSBP4 | 0.736999 | 5 | 0 | 4 |
| TMEM97 | SNRPE | 0.736439 | 12 | 0 | 12 |
| TMEM97 | XAB2 | 0.735943 | 3 | 0 | 3 |
| TMEM97 | ZNRF3 | 0.735409 | 3 | 0 | 3 |
| TMEM97 | NOSIP | 0.735238 | 3 | 0 | 3 |
For details and further investigation, click here
