| Full name: BICD cargo adaptor 2 | Alias Symbol: KIAA0699 | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 23299 | HGNC ID: HGNC:17208 | Ensembl Gene: ENSG00000185963 | OMIM ID: 609797 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BICD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BICD2 | 23299 | 213154_s_at | -0.0917 | 0.8561 | |
| GSE20347 | BICD2 | 23299 | 213154_s_at | -0.0795 | 0.7520 | |
| GSE23400 | BICD2 | 23299 | 213154_s_at | 0.3210 | 0.0108 | |
| GSE26886 | BICD2 | 23299 | 213154_s_at | -0.0539 | 0.8663 | |
| GSE29001 | BICD2 | 23299 | 213154_s_at | 0.1753 | 0.5264 | |
| GSE38129 | BICD2 | 23299 | 213154_s_at | 0.1018 | 0.6718 | |
| GSE45670 | BICD2 | 23299 | 213154_s_at | 0.5456 | 0.0006 | |
| GSE53622 | BICD2 | 23299 | 56599 | -0.0670 | 0.6222 | |
| GSE53624 | BICD2 | 23299 | 56599 | 0.0466 | 0.6349 | |
| GSE63941 | BICD2 | 23299 | 213154_s_at | -0.2950 | 0.6317 | |
| GSE77861 | BICD2 | 23299 | 213154_s_at | 0.4860 | 0.1082 | |
| GSE97050 | BICD2 | 23299 | A_24_P419120 | -0.1438 | 0.5473 | |
| SRP007169 | BICD2 | 23299 | RNAseq | 1.3728 | 0.0046 | |
| SRP008496 | BICD2 | 23299 | RNAseq | 1.2101 | 0.0009 | |
| SRP064894 | BICD2 | 23299 | RNAseq | 0.2931 | 0.2775 | |
| SRP133303 | BICD2 | 23299 | RNAseq | 0.2517 | 0.3278 | |
| SRP159526 | BICD2 | 23299 | RNAseq | -0.4228 | 0.2544 | |
| SRP193095 | BICD2 | 23299 | RNAseq | 0.2997 | 0.2470 | |
| SRP219564 | BICD2 | 23299 | RNAseq | -0.5018 | 0.2409 | |
| TCGA | BICD2 | 23299 | RNAseq | 0.3752 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by BICD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BICD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BICD2 | 23299 | 5 | 9 | 16 | |
| GSE20123 | BICD2 | 23299 | 5 | 9 | 16 | |
| GSE43470 | BICD2 | 23299 | 6 | 3 | 34 | |
| GSE46452 | BICD2 | 23299 | 6 | 14 | 39 | |
| GSE47630 | BICD2 | 23299 | 1 | 17 | 22 | |
| GSE54993 | BICD2 | 23299 | 4 | 2 | 64 | |
| GSE54994 | BICD2 | 23299 | 8 | 11 | 34 | |
| GSE60625 | BICD2 | 23299 | 0 | 0 | 11 | |
| GSE74703 | BICD2 | 23299 | 5 | 3 | 28 | |
| GSE74704 | BICD2 | 23299 | 2 | 7 | 11 | |
| TCGA | BICD2 | 23299 | 24 | 24 | 48 |
Total number of gains: 66; Total number of losses: 99; Total Number of normals: 323.
Somatic mutations of BICD2:
Generating mutation plots.
Highly correlated genes for BICD2:
Showing top 20/207 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BICD2 | SPIRE1 | 0.762351 | 3 | 0 | 3 |
| BICD2 | KCTD2 | 0.75104 | 3 | 0 | 3 |
| BICD2 | DEPDC4 | 0.74696 | 3 | 0 | 3 |
| BICD2 | PARP2 | 0.744679 | 3 | 0 | 3 |
| BICD2 | TRAF3IP1 | 0.73403 | 3 | 0 | 3 |
| BICD2 | MAPK9 | 0.731872 | 3 | 0 | 3 |
| BICD2 | CLASP1 | 0.728379 | 3 | 0 | 3 |
| BICD2 | ARL13B | 0.723246 | 3 | 0 | 3 |
| BICD2 | ZBTB11 | 0.716974 | 3 | 0 | 3 |
| BICD2 | DCTN1 | 0.704208 | 3 | 0 | 3 |
| BICD2 | ZNF319 | 0.702663 | 3 | 0 | 3 |
| BICD2 | EXOSC6 | 0.693091 | 3 | 0 | 3 |
| BICD2 | TSPAN17 | 0.690943 | 3 | 0 | 3 |
| BICD2 | RAB11FIP5 | 0.689933 | 3 | 0 | 3 |
| BICD2 | TAOK1 | 0.688976 | 3 | 0 | 3 |
| BICD2 | TRIB1 | 0.677266 | 3 | 0 | 3 |
| BICD2 | MRPL21 | 0.673649 | 3 | 0 | 3 |
| BICD2 | STUB1 | 0.66803 | 3 | 0 | 3 |
| BICD2 | SAMD4B | 0.66533 | 3 | 0 | 3 |
| BICD2 | XRCC4 | 0.664472 | 3 | 0 | 3 |
For details and further investigation, click here
