| Full name: protease associated domain containing 1 | Alias Symbol: MGC13004|PAP21|hPAP21 | ||
| Type: protein-coding gene | Cytoband: 2p13.2 | ||
| Entrez ID: 84279 | HGNC ID: HGNC:16047 | Ensembl Gene: ENSG00000135617 | OMIM ID: |
Expression of PRADC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRADC1 | 84279 | 223312_at | -0.1826 | 0.6541 | |
| GSE26886 | PRADC1 | 84279 | 223312_at | -0.8949 | 0.0000 | |
| GSE45670 | PRADC1 | 84279 | 223312_at | -0.3987 | 0.0051 | |
| GSE53622 | PRADC1 | 84279 | 112389 | -0.6292 | 0.0000 | |
| GSE53624 | PRADC1 | 84279 | 112389 | -0.3124 | 0.0017 | |
| GSE63941 | PRADC1 | 84279 | 223312_at | -0.9828 | 0.0434 | |
| GSE77861 | PRADC1 | 84279 | 223312_at | -0.4843 | 0.0449 | |
| GSE97050 | PRADC1 | 84279 | A_23_P131596 | 0.0459 | 0.9019 | |
| SRP007169 | PRADC1 | 84279 | RNAseq | -1.7114 | 0.0000 | |
| SRP008496 | PRADC1 | 84279 | RNAseq | -1.4127 | 0.0000 | |
| SRP064894 | PRADC1 | 84279 | RNAseq | -0.2468 | 0.5077 | |
| SRP133303 | PRADC1 | 84279 | RNAseq | -0.3888 | 0.0033 | |
| SRP159526 | PRADC1 | 84279 | RNAseq | -0.2789 | 0.2464 | |
| SRP193095 | PRADC1 | 84279 | RNAseq | -0.8402 | 0.0000 | |
| SRP219564 | PRADC1 | 84279 | RNAseq | -0.2831 | 0.5647 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PRADC1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PRADC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRADC1 | 84279 | 11 | 1 | 18 | |
| GSE20123 | PRADC1 | 84279 | 11 | 1 | 18 | |
| GSE43470 | PRADC1 | 84279 | 4 | 0 | 39 | |
| GSE46452 | PRADC1 | 84279 | 2 | 3 | 54 | |
| GSE47630 | PRADC1 | 84279 | 7 | 0 | 33 | |
| GSE54993 | PRADC1 | 84279 | 0 | 6 | 64 | |
| GSE54994 | PRADC1 | 84279 | 11 | 0 | 42 | |
| GSE60625 | PRADC1 | 84279 | 0 | 3 | 8 | |
| GSE74703 | PRADC1 | 84279 | 4 | 0 | 32 | |
| GSE74704 | PRADC1 | 84279 | 9 | 0 | 11 | |
| TCGA | PRADC1 | 84279 | 38 | 2 | 56 |
Total number of gains: 97; Total number of losses: 16; Total Number of normals: 375.
Somatic mutations of PRADC1:
Generating mutation plots.
Highly correlated genes for PRADC1:
Showing top 20/975 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRADC1 | HIBCH | 0.807131 | 3 | 0 | 3 |
| PRADC1 | ATP11B | 0.791328 | 3 | 0 | 3 |
| PRADC1 | SMPD1 | 0.788945 | 3 | 0 | 3 |
| PRADC1 | VPS26A | 0.765594 | 3 | 0 | 3 |
| PRADC1 | TPD52L2 | 0.761017 | 3 | 0 | 3 |
| PRADC1 | GGA3 | 0.75711 | 3 | 0 | 3 |
| PRADC1 | GCDH | 0.752319 | 3 | 0 | 3 |
| PRADC1 | NDUFA13 | 0.750367 | 5 | 0 | 5 |
| PRADC1 | TADA3 | 0.748826 | 3 | 0 | 3 |
| PRADC1 | AGPAT3 | 0.748568 | 3 | 0 | 3 |
| PRADC1 | OSBPL2 | 0.745933 | 4 | 0 | 4 |
| PRADC1 | PLEKHA5 | 0.74518 | 3 | 0 | 3 |
| PRADC1 | SLC25A3 | 0.744715 | 5 | 0 | 5 |
| PRADC1 | SERPINB1 | 0.744008 | 3 | 0 | 3 |
| PRADC1 | WDR47 | 0.74269 | 3 | 0 | 3 |
| PRADC1 | DEXI | 0.742368 | 3 | 0 | 3 |
| PRADC1 | GMPPB | 0.741998 | 3 | 0 | 3 |
| PRADC1 | HEMK1 | 0.74161 | 3 | 0 | 3 |
| PRADC1 | TBC1D20 | 0.741039 | 3 | 0 | 3 |
| PRADC1 | STXBP3 | 0.740247 | 4 | 0 | 4 |
For details and further investigation, click here
