| Full name: NMD3 ribosome export adaptor | Alias Symbol: CGI-07 | ||
| Type: protein-coding gene | Cytoband: 3q26.1 | ||
| Entrez ID: 51068 | HGNC ID: HGNC:24250 | Ensembl Gene: ENSG00000169251 | OMIM ID: 611021 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NMD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NMD3 | 51068 | 231870_s_at | 0.5312 | 0.1977 | |
| GSE20347 | NMD3 | 51068 | 218036_x_at | 0.7368 | 0.0055 | |
| GSE23400 | NMD3 | 51068 | 218036_x_at | 0.7876 | 0.0000 | |
| GSE26886 | NMD3 | 51068 | 231870_s_at | 0.7210 | 0.0000 | |
| GSE29001 | NMD3 | 51068 | 218036_x_at | 0.3966 | 0.2721 | |
| GSE38129 | NMD3 | 51068 | 218036_x_at | 0.8815 | 0.0001 | |
| GSE45670 | NMD3 | 51068 | 231870_s_at | 0.2298 | 0.1804 | |
| GSE53622 | NMD3 | 51068 | 8616 | 0.4467 | 0.0000 | |
| GSE53624 | NMD3 | 51068 | 8616 | 0.4035 | 0.0000 | |
| GSE63941 | NMD3 | 51068 | 231870_s_at | 0.2254 | 0.6265 | |
| GSE77861 | NMD3 | 51068 | 231870_s_at | 0.2069 | 0.1617 | |
| GSE97050 | NMD3 | 51068 | A_23_P32861 | 0.4071 | 0.1832 | |
| SRP007169 | NMD3 | 51068 | RNAseq | 1.0514 | 0.0047 | |
| SRP008496 | NMD3 | 51068 | RNAseq | 1.1557 | 0.0000 | |
| SRP064894 | NMD3 | 51068 | RNAseq | 0.2204 | 0.1963 | |
| SRP133303 | NMD3 | 51068 | RNAseq | 0.6929 | 0.0010 | |
| SRP159526 | NMD3 | 51068 | RNAseq | 0.5574 | 0.0937 | |
| SRP193095 | NMD3 | 51068 | RNAseq | 0.1039 | 0.4254 | |
| SRP219564 | NMD3 | 51068 | RNAseq | 0.0408 | 0.9141 | |
| TCGA | NMD3 | 51068 | RNAseq | -0.0529 | 0.2583 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NMD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NMD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NMD3 | 51068 | 22 | 0 | 8 | |
| GSE20123 | NMD3 | 51068 | 22 | 0 | 8 | |
| GSE43470 | NMD3 | 51068 | 23 | 0 | 20 | |
| GSE46452 | NMD3 | 51068 | 18 | 2 | 39 | |
| GSE47630 | NMD3 | 51068 | 19 | 3 | 18 | |
| GSE54993 | NMD3 | 51068 | 1 | 11 | 58 | |
| GSE54994 | NMD3 | 51068 | 38 | 1 | 14 | |
| GSE60625 | NMD3 | 51068 | 0 | 6 | 5 | |
| GSE74703 | NMD3 | 51068 | 20 | 0 | 16 | |
| GSE74704 | NMD3 | 51068 | 14 | 0 | 6 | |
| TCGA | NMD3 | 51068 | 77 | 0 | 19 |
Total number of gains: 254; Total number of losses: 23; Total Number of normals: 211.
Somatic mutations of NMD3:
Generating mutation plots.
Highly correlated genes for NMD3:
Showing top 20/1516 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NMD3 | ZNF628 | 0.800456 | 3 | 0 | 3 |
| NMD3 | AURKAIP1 | 0.79818 | 3 | 0 | 3 |
| NMD3 | DDX60L | 0.785102 | 3 | 0 | 3 |
| NMD3 | ZNF496 | 0.755114 | 3 | 0 | 3 |
| NMD3 | ZNF766 | 0.741857 | 3 | 0 | 3 |
| NMD3 | LRRC58 | 0.734485 | 5 | 0 | 5 |
| NMD3 | FAM161A | 0.727146 | 4 | 0 | 3 |
| NMD3 | DHX30 | 0.717634 | 3 | 0 | 3 |
| NMD3 | NOSIP | 0.716181 | 3 | 0 | 3 |
| NMD3 | NRM | 0.71262 | 3 | 0 | 3 |
| NMD3 | TIA1 | 0.705356 | 3 | 0 | 3 |
| NMD3 | UBTD2 | 0.702288 | 5 | 0 | 4 |
| NMD3 | RRAS2 | 0.702174 | 7 | 0 | 6 |
| NMD3 | PRR12 | 0.699836 | 3 | 0 | 3 |
| NMD3 | ACACA | 0.698715 | 3 | 0 | 3 |
| NMD3 | ORC2 | 0.697048 | 4 | 0 | 4 |
| NMD3 | CCNT1 | 0.695983 | 4 | 0 | 3 |
| NMD3 | TXNDC16 | 0.694964 | 3 | 0 | 3 |
| NMD3 | JKAMP | 0.692526 | 4 | 0 | 3 |
| NMD3 | CDC42EP3 | 0.692125 | 3 | 0 | 3 |
For details and further investigation, click here
