| Full name: CDGSH iron sulfur domain 3 | Alias Symbol: Miner2 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 284106 | HGNC ID: HGNC:27578 | Ensembl Gene: | OMIM ID: 611933 |
| Drug and gene relationship at DGIdb | |||
Expression of CISD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CISD3 | 284106 | 226727_at | -0.0379 | 0.9204 | |
| GSE26886 | CISD3 | 284106 | 226727_at | -0.3507 | 0.0383 | |
| GSE45670 | CISD3 | 284106 | 226727_at | 0.1333 | 0.5043 | |
| GSE63941 | CISD3 | 284106 | 226727_at | 0.1614 | 0.6580 | |
| GSE77861 | CISD3 | 284106 | 226727_at | -0.0486 | 0.7931 | |
| GSE97050 | CISD3 | 284106 | A_33_P3362636 | 0.1994 | 0.4610 | |
| SRP007169 | CISD3 | 284106 | RNAseq | 0.0527 | 0.8823 | |
| SRP008496 | CISD3 | 284106 | RNAseq | 0.2661 | 0.3650 | |
| SRP064894 | CISD3 | 284106 | RNAseq | 0.8998 | 0.0222 | |
| SRP133303 | CISD3 | 284106 | RNAseq | 0.0796 | 0.6251 | |
| SRP159526 | CISD3 | 284106 | RNAseq | 0.0581 | 0.8289 | |
| SRP193095 | CISD3 | 284106 | RNAseq | -0.2567 | 0.2084 | |
| SRP219564 | CISD3 | 284106 | RNAseq | -0.1980 | 0.6879 | |
| TCGA | CISD3 | 284106 | RNAseq | -0.1521 | 0.0063 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CISD3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CISD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CISD3 | 284106 | 7 | 1 | 22 | |
| GSE20123 | CISD3 | 284106 | 7 | 1 | 22 | |
| GSE43470 | CISD3 | 284106 | 0 | 1 | 42 | |
| GSE46452 | CISD3 | 284106 | 34 | 0 | 25 | |
| GSE47630 | CISD3 | 284106 | 8 | 1 | 31 | |
| GSE54993 | CISD3 | 284106 | 3 | 4 | 63 | |
| GSE54994 | CISD3 | 284106 | 8 | 5 | 40 | |
| GSE60625 | CISD3 | 284106 | 4 | 0 | 7 | |
| GSE74703 | CISD3 | 284106 | 0 | 0 | 36 | |
| GSE74704 | CISD3 | 284106 | 4 | 1 | 15 | |
| TCGA | CISD3 | 284106 | 19 | 9 | 68 |
Total number of gains: 94; Total number of losses: 23; Total Number of normals: 371.
Somatic mutations of CISD3:
Generating mutation plots.
Highly correlated genes for CISD3:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CISD3 | KLHL11 | 0.777094 | 3 | 0 | 3 |
| CISD3 | SIK1 | 0.750532 | 3 | 0 | 3 |
| CISD3 | B4GALNT4 | 0.749431 | 3 | 0 | 3 |
| CISD3 | LSM12 | 0.743715 | 3 | 0 | 3 |
| CISD3 | STOML1 | 0.742391 | 3 | 0 | 3 |
| CISD3 | ROBO4 | 0.741411 | 3 | 0 | 3 |
| CISD3 | NES | 0.725115 | 3 | 0 | 3 |
| CISD3 | DHX30 | 0.723729 | 3 | 0 | 3 |
| CISD3 | MAPRE3 | 0.721615 | 3 | 0 | 3 |
| CISD3 | CACHD1 | 0.721484 | 3 | 0 | 3 |
| CISD3 | CWC25 | 0.717826 | 3 | 0 | 3 |
| CISD3 | ATP1A4 | 0.711157 | 3 | 0 | 3 |
| CISD3 | CXCR5 | 0.708857 | 3 | 0 | 3 |
| CISD3 | RSPH9 | 0.700494 | 3 | 0 | 3 |
| CISD3 | CSDE1 | 0.694238 | 3 | 0 | 3 |
| CISD3 | POU3F4 | 0.692465 | 3 | 0 | 3 |
| CISD3 | RTF1 | 0.69059 | 3 | 0 | 3 |
| CISD3 | CRX | 0.687894 | 3 | 0 | 3 |
| CISD3 | RNF207 | 0.687501 | 3 | 0 | 3 |
| CISD3 | DMRTA1 | 0.683947 | 3 | 0 | 3 |
For details and further investigation, click here
