| Full name: dickkopf like acrosomal protein 1 | Alias Symbol: SGY-1|CT34 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 27120 | HGNC ID: HGNC:16528 | Ensembl Gene: ENSG00000104901 | OMIM ID: 605418 |
| Drug and gene relationship at DGIdb | |||
Expression of DKKL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DKKL1 | 27120 | 220284_at | 0.0756 | 0.8184 | |
| GSE20347 | DKKL1 | 27120 | 220284_at | -0.0080 | 0.9294 | |
| GSE23400 | DKKL1 | 27120 | 220284_at | -0.0907 | 0.0104 | |
| GSE26886 | DKKL1 | 27120 | 220284_at | 0.3528 | 0.0090 | |
| GSE29001 | DKKL1 | 27120 | 220284_at | -0.3043 | 0.0090 | |
| GSE38129 | DKKL1 | 27120 | 220284_at | -0.0950 | 0.2032 | |
| GSE45670 | DKKL1 | 27120 | 220284_at | 0.0486 | 0.5919 | |
| GSE53622 | DKKL1 | 27120 | 3275 | 0.1808 | 0.0328 | |
| GSE53624 | DKKL1 | 27120 | 3275 | 0.3246 | 0.0000 | |
| GSE63941 | DKKL1 | 27120 | 220284_at | 0.2747 | 0.1493 | |
| GSE77861 | DKKL1 | 27120 | 220284_at | 0.1145 | 0.5573 | |
| GSE97050 | DKKL1 | A_21_P0000139 | 0.0842 | 0.7382 | ||
| TCGA | DKKL1 | 27120 | RNAseq | 0.5959 | 0.3879 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DKKL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DKKL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DKKL1 | 27120 | 4 | 4 | 22 | |
| GSE20123 | DKKL1 | 27120 | 4 | 3 | 23 | |
| GSE43470 | DKKL1 | 27120 | 4 | 11 | 28 | |
| GSE46452 | DKKL1 | 27120 | 45 | 1 | 13 | |
| GSE47630 | DKKL1 | 27120 | 10 | 6 | 24 | |
| GSE54993 | DKKL1 | 27120 | 17 | 4 | 49 | |
| GSE54994 | DKKL1 | 27120 | 4 | 14 | 35 | |
| GSE60625 | DKKL1 | 27120 | 9 | 0 | 2 | |
| GSE74703 | DKKL1 | 27120 | 4 | 7 | 25 | |
| GSE74704 | DKKL1 | 27120 | 4 | 1 | 15 | |
| TCGA | DKKL1 | 27120 | 15 | 19 | 62 |
Total number of gains: 120; Total number of losses: 70; Total Number of normals: 298.
Somatic mutations of DKKL1:
Generating mutation plots.
Highly correlated genes for DKKL1:
Showing top 20/356 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DKKL1 | LRRC18 | 0.713388 | 3 | 0 | 3 |
| DKKL1 | PENK | 0.677773 | 3 | 0 | 3 |
| DKKL1 | RIN1 | 0.673534 | 3 | 0 | 3 |
| DKKL1 | CPAMD8 | 0.672401 | 3 | 0 | 3 |
| DKKL1 | PCDH10 | 0.66875 | 3 | 0 | 3 |
| DKKL1 | TMEM102 | 0.667377 | 4 | 0 | 3 |
| DKKL1 | DMGDH | 0.665786 | 3 | 0 | 3 |
| DKKL1 | SNAP25 | 0.660167 | 4 | 0 | 4 |
| DKKL1 | PROC | 0.654825 | 4 | 0 | 3 |
| DKKL1 | NPAS4 | 0.652143 | 3 | 0 | 3 |
| DKKL1 | SP7 | 0.651957 | 3 | 0 | 3 |
| DKKL1 | FRS3 | 0.651019 | 3 | 0 | 3 |
| DKKL1 | PM20D1 | 0.641257 | 3 | 0 | 3 |
| DKKL1 | CCDC142 | 0.638122 | 3 | 0 | 3 |
| DKKL1 | MAMSTR | 0.632325 | 3 | 0 | 3 |
| DKKL1 | CELA3B | 0.624638 | 5 | 0 | 5 |
| DKKL1 | CNIH2 | 0.62136 | 4 | 0 | 4 |
| DKKL1 | CLCN1 | 0.619077 | 4 | 0 | 3 |
| DKKL1 | MOS | 0.616441 | 5 | 0 | 4 |
| DKKL1 | SNORA71A | 0.616183 | 4 | 0 | 3 |
For details and further investigation, click here
