| Full name: CWC22 spliceosome associated protein homolog | Alias Symbol: KIAA1604|EIF4GL|fSAPb|NCM | ||
| Type: protein-coding gene | Cytoband: 2q31.3 | ||
| Entrez ID: 57703 | HGNC ID: HGNC:29322 | Ensembl Gene: ENSG00000163510 | OMIM ID: 615186 |
| Drug and gene relationship at DGIdb | |||
Expression of CWC22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CWC22 | 57703 | 226588_at | -0.0052 | 0.9955 | |
| GSE26886 | CWC22 | 57703 | 226588_at | 0.7290 | 0.0011 | |
| GSE45670 | CWC22 | 57703 | 226588_at | -0.0696 | 0.6542 | |
| GSE53622 | CWC22 | 57703 | 79531 | -0.0370 | 0.5781 | |
| GSE53624 | CWC22 | 57703 | 79531 | 0.0259 | 0.6392 | |
| GSE63941 | CWC22 | 57703 | 226588_at | 0.1854 | 0.7255 | |
| GSE77861 | CWC22 | 57703 | 226588_at | 0.0512 | 0.8379 | |
| GSE97050 | CWC22 | 57703 | A_23_P373799 | -0.4217 | 0.2150 | |
| SRP007169 | CWC22 | 57703 | RNAseq | 0.8871 | 0.0290 | |
| SRP008496 | CWC22 | 57703 | RNAseq | 0.6459 | 0.0255 | |
| SRP064894 | CWC22 | 57703 | RNAseq | -0.1262 | 0.5102 | |
| SRP133303 | CWC22 | 57703 | RNAseq | 0.0682 | 0.4139 | |
| SRP159526 | CWC22 | 57703 | RNAseq | -0.1475 | 0.4499 | |
| SRP193095 | CWC22 | 57703 | RNAseq | -0.2559 | 0.0026 | |
| SRP219564 | CWC22 | 57703 | RNAseq | -0.3894 | 0.0928 | |
| TCGA | CWC22 | 57703 | RNAseq | 0.0076 | 0.8807 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CWC22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CWC22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CWC22 | 57703 | 6 | 1 | 23 | |
| GSE20123 | CWC22 | 57703 | 6 | 1 | 23 | |
| GSE43470 | CWC22 | 57703 | 5 | 1 | 37 | |
| GSE46452 | CWC22 | 57703 | 1 | 4 | 54 | |
| GSE47630 | CWC22 | 57703 | 4 | 4 | 32 | |
| GSE54993 | CWC22 | 57703 | 0 | 5 | 65 | |
| GSE54994 | CWC22 | 57703 | 11 | 5 | 37 | |
| GSE60625 | CWC22 | 57703 | 0 | 3 | 8 | |
| GSE74703 | CWC22 | 57703 | 4 | 1 | 31 | |
| GSE74704 | CWC22 | 57703 | 3 | 1 | 16 | |
| TCGA | CWC22 | 57703 | 27 | 6 | 63 |
Total number of gains: 67; Total number of losses: 32; Total Number of normals: 389.
Somatic mutations of CWC22:
Generating mutation plots.
Highly correlated genes for CWC22:
Showing top 20/204 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CWC22 | TIGD1 | 0.800563 | 3 | 0 | 3 |
| CWC22 | ANAPC4 | 0.795907 | 3 | 0 | 3 |
| CWC22 | CYP1A2 | 0.78866 | 3 | 0 | 3 |
| CWC22 | RP9 | 0.783836 | 3 | 0 | 3 |
| CWC22 | RBMS1 | 0.782766 | 3 | 0 | 3 |
| CWC22 | COCH | 0.781839 | 3 | 0 | 3 |
| CWC22 | DLGAP4 | 0.780226 | 3 | 0 | 3 |
| CWC22 | ALKBH6 | 0.7707 | 3 | 0 | 3 |
| CWC22 | DYNC1I2 | 0.760846 | 4 | 0 | 3 |
| CWC22 | PNPLA8 | 0.750367 | 3 | 0 | 3 |
| CWC22 | DGKH | 0.747877 | 3 | 0 | 3 |
| CWC22 | LRP5L | 0.7471 | 3 | 0 | 3 |
| CWC22 | DNAJC2 | 0.746697 | 3 | 0 | 3 |
| CWC22 | DEGS1 | 0.746256 | 3 | 0 | 3 |
| CWC22 | ZNF280C | 0.742524 | 3 | 0 | 3 |
| CWC22 | MLH3 | 0.732231 | 3 | 0 | 3 |
| CWC22 | SYNE2 | 0.72912 | 3 | 0 | 3 |
| CWC22 | VPS13B | 0.726902 | 3 | 0 | 3 |
| CWC22 | RPL24 | 0.726602 | 3 | 0 | 3 |
| CWC22 | CEP95 | 0.726055 | 3 | 0 | 3 |
For details and further investigation, click here
