| Full name: signal recognition particle 19 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q22.2 | ||
| Entrez ID: 6728 | HGNC ID: HGNC:11300 | Ensembl Gene: ENSG00000153037 | OMIM ID: 182175 |
| Drug and gene relationship at DGIdb | |||
Expression of SRP19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRP19 | 6728 | 205335_s_at | 0.1447 | 0.8106 | |
| GSE20347 | SRP19 | 6728 | 205335_s_at | -0.1589 | 0.2723 | |
| GSE23400 | SRP19 | 6728 | 205335_s_at | 0.2375 | 0.0047 | |
| GSE26886 | SRP19 | 6728 | 205335_s_at | 0.4821 | 0.0090 | |
| GSE29001 | SRP19 | 6728 | 205335_s_at | 0.0485 | 0.8623 | |
| GSE38129 | SRP19 | 6728 | 205335_s_at | 0.1145 | 0.2675 | |
| GSE45670 | SRP19 | 6728 | 205335_s_at | 0.3014 | 0.0330 | |
| GSE63941 | SRP19 | 6728 | 205335_s_at | -0.4670 | 0.3395 | |
| GSE77861 | SRP19 | 6728 | 205335_s_at | -0.0780 | 0.8151 | |
| GSE97050 | SRP19 | 6728 | A_23_P93009 | -0.1462 | 0.6638 | |
| SRP007169 | SRP19 | 6728 | RNAseq | -0.9210 | 0.0098 | |
| SRP008496 | SRP19 | 6728 | RNAseq | -0.7268 | 0.0041 | |
| SRP064894 | SRP19 | 6728 | RNAseq | 0.0327 | 0.8237 | |
| SRP133303 | SRP19 | 6728 | RNAseq | 0.5141 | 0.0041 | |
| SRP159526 | SRP19 | 6728 | RNAseq | -0.1795 | 0.4182 | |
| SRP193095 | SRP19 | 6728 | RNAseq | -0.3517 | 0.0001 | |
| SRP219564 | SRP19 | 6728 | RNAseq | 0.1714 | 0.5841 | |
| TCGA | SRP19 | 6728 | RNAseq | 0.0209 | 0.7094 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SRP19 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SRP19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRP19 | 6728 | 1 | 13 | 16 | |
| GSE20123 | SRP19 | 6728 | 1 | 13 | 16 | |
| GSE43470 | SRP19 | 6728 | 3 | 8 | 32 | |
| GSE46452 | SRP19 | 6728 | 0 | 28 | 31 | |
| GSE47630 | SRP19 | 6728 | 0 | 21 | 19 | |
| GSE54993 | SRP19 | 6728 | 9 | 1 | 60 | |
| GSE54994 | SRP19 | 6728 | 1 | 17 | 35 | |
| GSE60625 | SRP19 | 6728 | 0 | 0 | 11 | |
| GSE74703 | SRP19 | 6728 | 2 | 6 | 28 | |
| GSE74704 | SRP19 | 6728 | 1 | 7 | 12 | |
| TCGA | SRP19 | 6728 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 155; Total Number of normals: 313.
Somatic mutations of SRP19:
Generating mutation plots.
Highly correlated genes for SRP19:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRP19 | DLGAP4 | 0.73338 | 3 | 0 | 3 |
| SRP19 | TMEM33 | 0.706066 | 6 | 0 | 6 |
| SRP19 | COMMD9 | 0.694233 | 3 | 0 | 3 |
| SRP19 | FARS2 | 0.685556 | 3 | 0 | 3 |
| SRP19 | AGTRAP | 0.682964 | 3 | 0 | 3 |
| SRP19 | DEGS1 | 0.681307 | 4 | 0 | 4 |
| SRP19 | C6orf163 | 0.673419 | 3 | 0 | 3 |
| SRP19 | DNAJC15 | 0.66858 | 4 | 0 | 3 |
| SRP19 | KLRC4 | 0.666137 | 3 | 0 | 3 |
| SRP19 | COL2A1 | 0.651559 | 3 | 0 | 3 |
| SRP19 | DHX36 | 0.650198 | 3 | 0 | 3 |
| SRP19 | SREK1IP1 | 0.647191 | 4 | 0 | 3 |
| SRP19 | THBD | 0.646938 | 4 | 0 | 3 |
| SRP19 | LINC00958 | 0.644354 | 4 | 0 | 3 |
| SRP19 | NDUFA6 | 0.641654 | 3 | 0 | 3 |
| SRP19 | JOSD2 | 0.641123 | 3 | 0 | 3 |
| SRP19 | ZNF503 | 0.640651 | 3 | 0 | 3 |
| SRP19 | THOC2 | 0.634254 | 3 | 0 | 3 |
| SRP19 | RPF2 | 0.634187 | 5 | 0 | 4 |
| SRP19 | CD47 | 0.633551 | 7 | 0 | 5 |
For details and further investigation, click here
