| Full name: distal-less homeobox 2 | Alias Symbol: TES-1 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 1746 | HGNC ID: HGNC:2915 | Ensembl Gene: ENSG00000115844 | OMIM ID: 126255 |
| Drug and gene relationship at DGIdb | |||
Expression of DLX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLX2 | 1746 | 215685_s_at | -0.0483 | 0.8743 | |
| GSE20347 | DLX2 | 1746 | 215685_s_at | -0.1176 | 0.1792 | |
| GSE23400 | DLX2 | 1746 | 215685_s_at | -0.0483 | 0.2851 | |
| GSE26886 | DLX2 | 1746 | 215685_s_at | -0.0694 | 0.7152 | |
| GSE29001 | DLX2 | 1746 | 215685_s_at | -0.4618 | 0.0006 | |
| GSE38129 | DLX2 | 1746 | 215685_s_at | -0.2436 | 0.1924 | |
| GSE45670 | DLX2 | 1746 | 215685_s_at | -0.0428 | 0.7278 | |
| GSE53622 | DLX2 | 1746 | 132003 | 3.4493 | 0.0000 | |
| GSE53624 | DLX2 | 1746 | 132003 | 3.8042 | 0.0000 | |
| GSE63941 | DLX2 | 1746 | 207147_at | 1.2698 | 0.2749 | |
| GSE77861 | DLX2 | 1746 | 215685_s_at | -0.1485 | 0.1799 | |
| GSE97050 | DLX2 | 1746 | A_23_P28598 | 0.3736 | 0.3064 | |
| TCGA | DLX2 | 1746 | RNAseq | 1.5468 | 0.0002 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by DLX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLX2 | 1746 | 9 | 0 | 21 | |
| GSE20123 | DLX2 | 1746 | 9 | 0 | 21 | |
| GSE43470 | DLX2 | 1746 | 6 | 1 | 36 | |
| GSE46452 | DLX2 | 1746 | 1 | 4 | 54 | |
| GSE47630 | DLX2 | 1746 | 5 | 3 | 32 | |
| GSE54993 | DLX2 | 1746 | 0 | 5 | 65 | |
| GSE54994 | DLX2 | 1746 | 11 | 3 | 39 | |
| GSE60625 | DLX2 | 1746 | 0 | 3 | 8 | |
| GSE74703 | DLX2 | 1746 | 5 | 1 | 30 | |
| GSE74704 | DLX2 | 1746 | 5 | 0 | 15 | |
| TCGA | DLX2 | 1746 | 28 | 6 | 62 |
Total number of gains: 79; Total number of losses: 26; Total Number of normals: 383.
Somatic mutations of DLX2:
Generating mutation plots.
Highly correlated genes for DLX2:
Showing top 20/377 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLX2 | C16orf74 | 0.73612 | 3 | 0 | 3 |
| DLX2 | CENPA | 0.734108 | 3 | 0 | 3 |
| DLX2 | VAX1 | 0.724832 | 3 | 0 | 3 |
| DLX2 | TREM2 | 0.711905 | 3 | 0 | 3 |
| DLX2 | SPON2 | 0.696428 | 3 | 0 | 3 |
| DLX2 | SMARCD1 | 0.694821 | 3 | 0 | 3 |
| DLX2 | LY9 | 0.688653 | 6 | 0 | 6 |
| DLX2 | FAM89A | 0.687789 | 3 | 0 | 3 |
| DLX2 | RTN4R | 0.68505 | 3 | 0 | 3 |
| DLX2 | ZNF707 | 0.682274 | 3 | 0 | 3 |
| DLX2 | BRAT1 | 0.679099 | 3 | 0 | 3 |
| DLX2 | MTBP | 0.678065 | 4 | 0 | 3 |
| DLX2 | SNAP47 | 0.677869 | 3 | 0 | 3 |
| DLX2 | KHDC1 | 0.676722 | 3 | 0 | 3 |
| DLX2 | PODNL1 | 0.675873 | 4 | 0 | 4 |
| DLX2 | B3GALT6 | 0.67327 | 3 | 0 | 3 |
| DLX2 | HABP2 | 0.672346 | 3 | 0 | 3 |
| DLX2 | SAAL1 | 0.671292 | 3 | 0 | 3 |
| DLX2 | C18orf54 | 0.66607 | 3 | 0 | 3 |
| DLX2 | MORN1 | 0.662987 | 4 | 0 | 4 |
For details and further investigation, click here
