| Full name: ventral anterior homeobox 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 11023 | HGNC ID: HGNC:12660 | Ensembl Gene: ENSG00000148704 | OMIM ID: 604294 |
| Drug and gene relationship at DGIdb | |||
Expression of VAX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | VAX1 | 11023 | 102015 | 1.4077 | 0.0000 | |
| GSE53624 | VAX1 | 11023 | 102015 | 2.3491 | 0.0000 | |
| GSE97050 | VAX1 | 11023 | A_33_P3381393 | 0.2882 | 0.4339 | |
| SRP159526 | VAX1 | 11023 | RNAseq | 7.0232 | 0.0000 | |
| TCGA | VAX1 | 11023 | RNAseq | 4.7988 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by VAX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VAX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VAX1 | 11023 | 1 | 7 | 22 | |
| GSE20123 | VAX1 | 11023 | 1 | 7 | 22 | |
| GSE43470 | VAX1 | 11023 | 0 | 9 | 34 | |
| GSE46452 | VAX1 | 11023 | 0 | 11 | 48 | |
| GSE47630 | VAX1 | 11023 | 2 | 14 | 24 | |
| GSE54993 | VAX1 | 11023 | 8 | 0 | 62 | |
| GSE54994 | VAX1 | 11023 | 1 | 9 | 43 | |
| GSE60625 | VAX1 | 11023 | 0 | 0 | 11 | |
| GSE74703 | VAX1 | 11023 | 0 | 6 | 30 | |
| GSE74704 | VAX1 | 11023 | 1 | 3 | 16 | |
| TCGA | VAX1 | 11023 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 94; Total Number of normals: 376.
Somatic mutations of VAX1:
Generating mutation plots.
Highly correlated genes for VAX1:
Showing top 20/294 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VAX1 | PFN2 | 0.736059 | 3 | 0 | 3 |
| VAX1 | DLX2 | 0.724832 | 3 | 0 | 3 |
| VAX1 | TRMT112 | 0.721137 | 3 | 0 | 3 |
| VAX1 | HOXB7 | 0.717899 | 3 | 0 | 3 |
| VAX1 | CABYR | 0.710888 | 3 | 0 | 3 |
| VAX1 | WDR54 | 0.708439 | 3 | 0 | 3 |
| VAX1 | STC2 | 0.706799 | 3 | 0 | 3 |
| VAX1 | CHD1L | 0.706481 | 3 | 0 | 3 |
| VAX1 | DVL3 | 0.706367 | 3 | 0 | 3 |
| VAX1 | XPR1 | 0.706207 | 3 | 0 | 3 |
| VAX1 | LHX2 | 0.704891 | 3 | 0 | 3 |
| VAX1 | RNF2 | 0.703026 | 3 | 0 | 3 |
| VAX1 | ACTL6A | 0.702115 | 3 | 0 | 3 |
| VAX1 | PFDN2 | 0.699234 | 3 | 0 | 3 |
| VAX1 | XPO6 | 0.696581 | 3 | 0 | 3 |
| VAX1 | DNMT1 | 0.696515 | 3 | 0 | 3 |
| VAX1 | SENP3 | 0.695868 | 3 | 0 | 3 |
| VAX1 | DNAJB11 | 0.695813 | 3 | 0 | 3 |
| VAX1 | XPO1 | 0.694303 | 3 | 0 | 3 |
| VAX1 | PLOD1 | 0.693917 | 3 | 0 | 3 |
For details and further investigation, click here
