| Full name: KH domain containing 1 | Alias Symbol: MGC10818|bA257K9.4|NDG1|Em:AC019205.8 | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 80759 | HGNC ID: HGNC:21366 | Ensembl Gene: ENSG00000135314 | OMIM ID: 611688 |
Expression of KHDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KHDC1 | 80759 | 230055_at | 0.1422 | 0.6397 | |
| GSE26886 | KHDC1 | 80759 | 230055_at | 0.3815 | 0.0882 | |
| GSE45670 | KHDC1 | 80759 | 230055_at | 0.1725 | 0.1796 | |
| GSE53622 | KHDC1 | 80759 | 124799 | 1.3521 | 0.0000 | |
| GSE53624 | KHDC1 | 80759 | 124799 | 1.4966 | 0.0000 | |
| GSE63941 | KHDC1 | 80759 | 230055_at | -0.4917 | 0.2951 | |
| GSE77861 | KHDC1 | 80759 | 230055_at | -0.0450 | 0.6891 | |
| GSE97050 | KHDC1 | 80759 | A_33_P3248842 | 0.4507 | 0.1837 | |
| SRP007169 | KHDC1 | 80759 | RNAseq | 1.0631 | 0.1209 | |
| SRP064894 | KHDC1 | 80759 | RNAseq | 1.2331 | 0.0000 | |
| SRP133303 | KHDC1 | 80759 | RNAseq | 0.2426 | 0.0251 | |
| SRP159526 | KHDC1 | 80759 | RNAseq | 1.4090 | 0.0007 | |
| SRP193095 | KHDC1 | 80759 | RNAseq | 0.1615 | 0.2424 | |
| SRP219564 | KHDC1 | 80759 | RNAseq | 0.4833 | 0.2002 | |
| TCGA | KHDC1 | 80759 | RNAseq | 0.4788 | 0.0039 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by KHDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KHDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KHDC1 | 80759 | 1 | 3 | 26 | |
| GSE20123 | KHDC1 | 80759 | 1 | 2 | 27 | |
| GSE43470 | KHDC1 | 80759 | 3 | 0 | 40 | |
| GSE46452 | KHDC1 | 80759 | 2 | 11 | 46 | |
| GSE47630 | KHDC1 | 80759 | 8 | 4 | 28 | |
| GSE54993 | KHDC1 | 80759 | 3 | 2 | 65 | |
| GSE54994 | KHDC1 | 80759 | 8 | 9 | 36 | |
| GSE60625 | KHDC1 | 80759 | 0 | 1 | 10 | |
| GSE74703 | KHDC1 | 80759 | 3 | 0 | 33 | |
| GSE74704 | KHDC1 | 80759 | 0 | 1 | 19 | |
| TCGA | KHDC1 | 80759 | 10 | 21 | 65 |
Total number of gains: 39; Total number of losses: 54; Total Number of normals: 395.
Somatic mutations of KHDC1:
Generating mutation plots.
Highly correlated genes for KHDC1:
Showing top 20/493 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KHDC1 | GLIPR1 | 0.759798 | 3 | 0 | 3 |
| KHDC1 | DHRSX | 0.757144 | 3 | 0 | 3 |
| KHDC1 | SNRPB2 | 0.746772 | 3 | 0 | 3 |
| KHDC1 | HLTF | 0.739245 | 3 | 0 | 3 |
| KHDC1 | RBL1 | 0.72972 | 3 | 0 | 3 |
| KHDC1 | C18orf54 | 0.728901 | 3 | 0 | 3 |
| KHDC1 | LAPTM4B | 0.726357 | 3 | 0 | 3 |
| KHDC1 | CDC27 | 0.721768 | 3 | 0 | 3 |
| KHDC1 | SHC1 | 0.720202 | 3 | 0 | 3 |
| KHDC1 | DARS2 | 0.717796 | 3 | 0 | 3 |
| KHDC1 | RAB34 | 0.715684 | 3 | 0 | 3 |
| KHDC1 | CSE1L | 0.715672 | 3 | 0 | 3 |
| KHDC1 | KCNN1 | 0.714717 | 3 | 0 | 3 |
| KHDC1 | HSPD1 | 0.709032 | 3 | 0 | 3 |
| KHDC1 | AGT | 0.708532 | 3 | 0 | 3 |
| KHDC1 | NEK3 | 0.703295 | 3 | 0 | 3 |
| KHDC1 | SCNM1 | 0.701937 | 3 | 0 | 3 |
| KHDC1 | MPHOSPH9 | 0.700895 | 3 | 0 | 3 |
| KHDC1 | PYCR2 | 0.699423 | 3 | 0 | 3 |
| KHDC1 | NKX2-5 | 0.698574 | 3 | 0 | 3 |
For details and further investigation, click here
