| Full name: R3H domain containing 4 | Alias Symbol: MGC16353 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 91300 | HGNC ID: HGNC:28270 | Ensembl Gene: ENSG00000198858 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of R3HDM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | R3HDM4 | 91300 | 55705_at | 0.1457 | 0.5455 | |
| GSE20347 | R3HDM4 | 91300 | 55705_at | -0.2203 | 0.0679 | |
| GSE23400 | R3HDM4 | 91300 | 55705_at | -0.0310 | 0.4619 | |
| GSE26886 | R3HDM4 | 91300 | 55705_at | -0.6032 | 0.0006 | |
| GSE29001 | R3HDM4 | 91300 | 55705_at | -0.1981 | 0.5577 | |
| GSE38129 | R3HDM4 | 91300 | 55705_at | -0.1192 | 0.3402 | |
| GSE45670 | R3HDM4 | 91300 | 55705_at | 0.3055 | 0.0020 | |
| GSE53622 | R3HDM4 | 91300 | 129759 | -0.1439 | 0.1523 | |
| GSE53624 | R3HDM4 | 91300 | 129759 | -0.2081 | 0.0050 | |
| GSE63941 | R3HDM4 | 91300 | 55705_at | 0.5069 | 0.0302 | |
| GSE77861 | R3HDM4 | 91300 | 55705_at | 0.0997 | 0.6487 | |
| SRP007169 | R3HDM4 | 91300 | RNAseq | -1.2592 | 0.0026 | |
| SRP008496 | R3HDM4 | 91300 | RNAseq | -1.2973 | 0.0000 | |
| SRP064894 | R3HDM4 | 91300 | RNAseq | 0.1716 | 0.4600 | |
| SRP133303 | R3HDM4 | 91300 | RNAseq | -0.0303 | 0.8427 | |
| SRP159526 | R3HDM4 | 91300 | RNAseq | -0.5047 | 0.0436 | |
| SRP193095 | R3HDM4 | 91300 | RNAseq | -0.1812 | 0.2047 | |
| SRP219564 | R3HDM4 | 91300 | RNAseq | 0.0459 | 0.8870 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by R3HDM4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of R3HDM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | R3HDM4 | 91300 | 4 | 6 | 20 | |
| GSE20123 | R3HDM4 | 91300 | 4 | 5 | 21 | |
| GSE43470 | R3HDM4 | 91300 | 1 | 9 | 33 | |
| GSE46452 | R3HDM4 | 91300 | 47 | 1 | 11 | |
| GSE47630 | R3HDM4 | 91300 | 5 | 7 | 28 | |
| GSE54993 | R3HDM4 | 91300 | 13 | 4 | 53 | |
| GSE54994 | R3HDM4 | 91300 | 8 | 15 | 30 | |
| GSE60625 | R3HDM4 | 91300 | 9 | 0 | 2 | |
| GSE74703 | R3HDM4 | 91300 | 1 | 7 | 28 | |
| GSE74704 | R3HDM4 | 91300 | 3 | 3 | 14 | |
| TCGA | R3HDM4 | 91300 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 82; Total Number of normals: 303.
Somatic mutations of R3HDM4:
Generating mutation plots.
Highly correlated genes for R3HDM4:
Showing top 20/469 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| R3HDM4 | ABHD4 | 0.687333 | 4 | 0 | 3 |
| R3HDM4 | CYP2A13 | 0.665775 | 3 | 0 | 3 |
| R3HDM4 | FPGS | 0.661311 | 3 | 0 | 3 |
| R3HDM4 | CC2D1B | 0.648519 | 4 | 0 | 4 |
| R3HDM4 | ATG9A | 0.645388 | 5 | 0 | 5 |
| R3HDM4 | MKNK1 | 0.640419 | 4 | 0 | 3 |
| R3HDM4 | SLC39A5 | 0.63921 | 3 | 0 | 3 |
| R3HDM4 | RCC2 | 0.636861 | 3 | 0 | 3 |
| R3HDM4 | GPSM3 | 0.636524 | 3 | 0 | 3 |
| R3HDM4 | NFAM1 | 0.634823 | 3 | 0 | 3 |
| R3HDM4 | OLFM2 | 0.634675 | 5 | 0 | 4 |
| R3HDM4 | AATK | 0.630945 | 4 | 0 | 3 |
| R3HDM4 | HM13 | 0.630433 | 7 | 0 | 6 |
| R3HDM4 | TTC38 | 0.63001 | 3 | 0 | 3 |
| R3HDM4 | FUT6 | 0.629833 | 4 | 0 | 4 |
| R3HDM4 | NRG1 | 0.62875 | 3 | 0 | 3 |
| R3HDM4 | SYNGR2 | 0.627776 | 5 | 0 | 4 |
| R3HDM4 | CDC42BPB | 0.627215 | 4 | 0 | 3 |
| R3HDM4 | PIP4K2C | 0.62636 | 5 | 0 | 4 |
| R3HDM4 | BCL2L1 | 0.624055 | 7 | 0 | 6 |
For details and further investigation, click here
