| Full name: doublesex and mab-3 related transcription factor 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p24.3 | ||
| Entrez ID: 10655 | HGNC ID: HGNC:2935 | Ensembl Gene: ENSG00000173253 | OMIM ID: 604935 |
| Drug and gene relationship at DGIdb | |||
Expression of DMRT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMRT2 | 10655 | 223986_x_at | 0.2260 | 0.4990 | |
| GSE26886 | DMRT2 | 10655 | 223986_x_at | 1.0787 | 0.0000 | |
| GSE45670 | DMRT2 | 10655 | 223704_s_at | 1.0775 | 0.1439 | |
| GSE53622 | DMRT2 | 10655 | 164798 | 2.0372 | 0.0000 | |
| GSE53624 | DMRT2 | 10655 | 164798 | 2.2997 | 0.0000 | |
| GSE63941 | DMRT2 | 10655 | 223986_x_at | 0.8792 | 0.2411 | |
| GSE77861 | DMRT2 | 10655 | 223704_s_at | 1.1935 | 0.0100 | |
| SRP007169 | DMRT2 | 10655 | RNAseq | 4.9146 | 0.0000 | |
| SRP159526 | DMRT2 | 10655 | RNAseq | 4.6984 | 0.0000 | |
| TCGA | DMRT2 | 10655 | RNAseq | 2.0771 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by DMRT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMRT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMRT2 | 10655 | 1 | 15 | 14 | |
| GSE20123 | DMRT2 | 10655 | 1 | 14 | 15 | |
| GSE43470 | DMRT2 | 10655 | 3 | 14 | 26 | |
| GSE46452 | DMRT2 | 10655 | 2 | 23 | 34 | |
| GSE47630 | DMRT2 | 10655 | 4 | 27 | 9 | |
| GSE54993 | DMRT2 | 10655 | 6 | 3 | 61 | |
| GSE54994 | DMRT2 | 10655 | 9 | 18 | 26 | |
| GSE60625 | DMRT2 | 10655 | 0 | 2 | 9 | |
| GSE74703 | DMRT2 | 10655 | 3 | 10 | 23 | |
| GSE74704 | DMRT2 | 10655 | 0 | 12 | 8 | |
| TCGA | DMRT2 | 10655 | 13 | 51 | 32 |
Total number of gains: 42; Total number of losses: 189; Total Number of normals: 257.
Somatic mutations of DMRT2:
Generating mutation plots.
Highly correlated genes for DMRT2:
Showing top 20/411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMRT2 | SCLY | 0.716417 | 3 | 0 | 3 |
| DMRT2 | OGDH | 0.710997 | 3 | 0 | 3 |
| DMRT2 | FAXC | 0.698187 | 4 | 0 | 4 |
| DMRT2 | TMTC1 | 0.693095 | 3 | 0 | 3 |
| DMRT2 | PLTP | 0.691161 | 3 | 0 | 3 |
| DMRT2 | FBRSL1 | 0.689481 | 3 | 0 | 3 |
| DMRT2 | NTRK2 | 0.686123 | 7 | 0 | 7 |
| DMRT2 | DVL2 | 0.683221 | 3 | 0 | 3 |
| DMRT2 | PHIP | 0.683157 | 4 | 0 | 4 |
| DMRT2 | ZC3H12C | 0.672675 | 3 | 0 | 3 |
| DMRT2 | LTBR | 0.672144 | 3 | 0 | 3 |
| DMRT2 | SCN9A | 0.663514 | 6 | 0 | 5 |
| DMRT2 | SOX2-OT | 0.663075 | 7 | 0 | 6 |
| DMRT2 | BAHCC1 | 0.660156 | 3 | 0 | 3 |
| DMRT2 | ZNF148 | 0.657435 | 4 | 0 | 4 |
| DMRT2 | SCYL1 | 0.656247 | 3 | 0 | 3 |
| DMRT2 | QRFPR | 0.654855 | 6 | 0 | 6 |
| DMRT2 | C11orf95 | 0.653392 | 3 | 0 | 3 |
| DMRT2 | CHST7 | 0.651414 | 6 | 0 | 5 |
| DMRT2 | ZIC5 | 0.64913 | 3 | 0 | 3 |
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