SEMA6B

 

Full name: semaphorin 6B Alias Symbol: semaZ|SEMA-VIB|SEM-SEMA-Y
Type: protein-coding gene Cytoband: 19p13.3
Entrez ID: 10501 HGNC ID: HGNC:10739 Ensembl Gene: ENSG00000167680 OMIM ID: 608873
Drug and gene relationship at DGIdb

 

Expression of SEMA6B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SEMA6B 10501 224182_x_at -0.1243 0.6344
GSE20347 SEMA6B 10501 220778_x_at -0.1135 0.0949
GSE23400 SEMA6B 10501 220778_x_at -0.1118 0.0016
GSE26886 SEMA6B 10501 224182_x_at 0.2787 0.0201
GSE29001 SEMA6B 10501 220778_x_at -0.0784 0.7315
GSE38129 SEMA6B 10501 220778_x_at -0.1754 0.0117
GSE45670 SEMA6B 10501 224182_x_at -0.0521 0.5357
GSE53622 SEMA6B 10501 42350 0.3129 0.0003
GSE53624 SEMA6B 10501 42350 0.0744 0.2815
GSE63941 SEMA6B 10501 224182_x_at -0.0276 0.8896
GSE77861 SEMA6B 10501 220778_x_at -0.0990 0.4363
GSE97050 SEMA6B 10501 A_33_P3263651 0.1278 0.6679
SRP007169 SEMA6B 10501 RNAseq 1.8767 0.0218
SRP064894 SEMA6B 10501 RNAseq 1.5805 0.0001
SRP133303 SEMA6B 10501 RNAseq 0.5184 0.0690
SRP159526 SEMA6B 10501 RNAseq 0.6745 0.1310
SRP219564 SEMA6B 10501 RNAseq 0.4815 0.4919
TCGA SEMA6B 10501 RNAseq -0.2263 0.0319

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by SEMA6B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SEMA6B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SEMA6B 10501 5 3 22
GSE20123 SEMA6B 10501 4 2 24
GSE43470 SEMA6B 10501 1 8 34
GSE46452 SEMA6B 10501 47 1 11
GSE47630 SEMA6B 10501 5 7 28
GSE54993 SEMA6B 10501 16 3 51
GSE54994 SEMA6B 10501 6 16 31
GSE60625 SEMA6B 10501 9 0 2
GSE74703 SEMA6B 10501 1 5 30
GSE74704 SEMA6B 10501 1 2 17
TCGA SEMA6B 10501 12 18 66

Total number of gains: 107; Total number of losses: 65; Total Number of normals: 316.  


 

Somatic mutations of SEMA6B:

 

Generating mutation plots.

 

Highly correlated genes for SEMA6B:

 

Showing top 20/934 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SEMA6BTSPYL20.790412303
SEMA6BZNF3580.704216303
SEMA6BHGF0.697432404
SEMA6BUBASH3B0.69738303
SEMA6BZMAT40.693199303
SEMA6BTMEM2140.692302303
SEMA6BARC0.681746303
SEMA6BTFAP40.681449303
SEMA6BFAM163A0.675587303
SEMA6BZP20.672119303
SEMA6BSYDE10.665825303
SEMA6BCOL26A10.665723403
SEMA6BZNF6530.662413303
SEMA6BCPA20.661844303
SEMA6BMYH80.660347303
SEMA6BASCL10.659295303
SEMA6BLINC006520.657747404
SEMA6BCYP27A10.656863303
SEMA6BRFX20.656858404
SEMA6BMIR146A0.649065403

For details and further investigation, click here