Full name: semaphorin 6B | Alias Symbol: semaZ|SEMA-VIB|SEM-SEMA-Y | ||
Type: protein-coding gene | Cytoband: 19p13.3 | ||
Entrez ID: 10501 | HGNC ID: HGNC:10739 | Ensembl Gene: ENSG00000167680 | OMIM ID: 608873 |
Drug and gene relationship at DGIdb |
Expression of SEMA6B:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | SEMA6B | 10501 | 224182_x_at | -0.1243 | 0.6344 | |
GSE20347 | SEMA6B | 10501 | 220778_x_at | -0.1135 | 0.0949 | |
GSE23400 | SEMA6B | 10501 | 220778_x_at | -0.1118 | 0.0016 | |
GSE26886 | SEMA6B | 10501 | 224182_x_at | 0.2787 | 0.0201 | |
GSE29001 | SEMA6B | 10501 | 220778_x_at | -0.0784 | 0.7315 | |
GSE38129 | SEMA6B | 10501 | 220778_x_at | -0.1754 | 0.0117 | |
GSE45670 | SEMA6B | 10501 | 224182_x_at | -0.0521 | 0.5357 | |
GSE53622 | SEMA6B | 10501 | 42350 | 0.3129 | 0.0003 | |
GSE53624 | SEMA6B | 10501 | 42350 | 0.0744 | 0.2815 | |
GSE63941 | SEMA6B | 10501 | 224182_x_at | -0.0276 | 0.8896 | |
GSE77861 | SEMA6B | 10501 | 220778_x_at | -0.0990 | 0.4363 | |
GSE97050 | SEMA6B | 10501 | A_33_P3263651 | 0.1278 | 0.6679 | |
SRP007169 | SEMA6B | 10501 | RNAseq | 1.8767 | 0.0218 | |
SRP064894 | SEMA6B | 10501 | RNAseq | 1.5805 | 0.0001 | |
SRP133303 | SEMA6B | 10501 | RNAseq | 0.5184 | 0.0690 | |
SRP159526 | SEMA6B | 10501 | RNAseq | 0.6745 | 0.1310 | |
SRP219564 | SEMA6B | 10501 | RNAseq | 0.4815 | 0.4919 | |
TCGA | SEMA6B | 10501 | RNAseq | -0.2263 | 0.0319 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SEMA6B expression:
Note: Click image to view full size file.
Copy number change of SEMA6B:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | SEMA6B | 10501 | 5 | 3 | 22 | |
GSE20123 | SEMA6B | 10501 | 4 | 2 | 24 | |
GSE43470 | SEMA6B | 10501 | 1 | 8 | 34 | |
GSE46452 | SEMA6B | 10501 | 47 | 1 | 11 | |
GSE47630 | SEMA6B | 10501 | 5 | 7 | 28 | |
GSE54993 | SEMA6B | 10501 | 16 | 3 | 51 | |
GSE54994 | SEMA6B | 10501 | 6 | 16 | 31 | |
GSE60625 | SEMA6B | 10501 | 9 | 0 | 2 | |
GSE74703 | SEMA6B | 10501 | 1 | 5 | 30 | |
GSE74704 | SEMA6B | 10501 | 1 | 2 | 17 | |
TCGA | SEMA6B | 10501 | 12 | 18 | 66 |
Total number of gains: 107; Total number of losses: 65; Total Number of normals: 316.
Somatic mutations of SEMA6B:
Generating mutation plots.
Highly correlated genes for SEMA6B:
Showing top 20/934 corelated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
SEMA6B | TSPYL2 | 0.790412 | 3 | 0 | 3 |
SEMA6B | ZNF358 | 0.704216 | 3 | 0 | 3 |
SEMA6B | HGF | 0.697432 | 4 | 0 | 4 |
SEMA6B | UBASH3B | 0.69738 | 3 | 0 | 3 |
SEMA6B | ZMAT4 | 0.693199 | 3 | 0 | 3 |
SEMA6B | TMEM214 | 0.692302 | 3 | 0 | 3 |
SEMA6B | ARC | 0.681746 | 3 | 0 | 3 |
SEMA6B | TFAP4 | 0.681449 | 3 | 0 | 3 |
SEMA6B | FAM163A | 0.675587 | 3 | 0 | 3 |
SEMA6B | ZP2 | 0.672119 | 3 | 0 | 3 |
SEMA6B | SYDE1 | 0.665825 | 3 | 0 | 3 |
SEMA6B | COL26A1 | 0.665723 | 4 | 0 | 3 |
SEMA6B | ZNF653 | 0.662413 | 3 | 0 | 3 |
SEMA6B | CPA2 | 0.661844 | 3 | 0 | 3 |
SEMA6B | MYH8 | 0.660347 | 3 | 0 | 3 |
SEMA6B | ASCL1 | 0.659295 | 3 | 0 | 3 |
SEMA6B | LINC00652 | 0.657747 | 4 | 0 | 4 |
SEMA6B | CYP27A1 | 0.656863 | 3 | 0 | 3 |
SEMA6B | RFX2 | 0.656858 | 4 | 0 | 4 |
SEMA6B | MIR146A | 0.649065 | 4 | 0 | 3 |
For details and further investigation, click here