| Full name: alpha hemoglobin stabilizing protein | Alias Symbol: EDRF | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 51327 | HGNC ID: HGNC:18075 | Ensembl Gene: ENSG00000169877 | OMIM ID: 605821 |
| Drug and gene relationship at DGIdb | |||
Expression of AHSP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AHSP | 51327 | 219672_at | -0.0373 | 0.8925 | |
| GSE20347 | AHSP | 51327 | 219672_at | 0.0269 | 0.7161 | |
| GSE23400 | AHSP | 51327 | 219672_at | -0.0899 | 0.0094 | |
| GSE26886 | AHSP | 51327 | 219672_at | -0.1608 | 0.1336 | |
| GSE29001 | AHSP | 51327 | 219672_at | -0.3647 | 0.0116 | |
| GSE38129 | AHSP | 51327 | 219672_at | -0.0529 | 0.3899 | |
| GSE45670 | AHSP | 51327 | 219672_at | 0.0124 | 0.9142 | |
| GSE53622 | AHSP | 51327 | 22274 | -0.3003 | 0.0005 | |
| GSE53624 | AHSP | 51327 | 22274 | -0.0698 | 0.4212 | |
| GSE63941 | AHSP | 51327 | 219672_at | 0.2554 | 0.0647 | |
| GSE77861 | AHSP | 51327 | 219672_at | -0.0722 | 0.6403 | |
| GSE97050 | AHSP | 51327 | A_23_P135486 | -0.2267 | 0.2991 | |
| TCGA | AHSP | 51327 | RNAseq | -1.3930 | 0.1973 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AHSP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AHSP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AHSP | 51327 | 4 | 4 | 22 | |
| GSE20123 | AHSP | 51327 | 3 | 3 | 24 | |
| GSE43470 | AHSP | 51327 | 3 | 3 | 37 | |
| GSE46452 | AHSP | 51327 | 38 | 1 | 20 | |
| GSE47630 | AHSP | 51327 | 11 | 7 | 22 | |
| GSE54993 | AHSP | 51327 | 2 | 5 | 63 | |
| GSE54994 | AHSP | 51327 | 4 | 10 | 39 | |
| GSE60625 | AHSP | 51327 | 4 | 0 | 7 | |
| GSE74703 | AHSP | 51327 | 3 | 2 | 31 | |
| GSE74704 | AHSP | 51327 | 3 | 2 | 15 | |
| TCGA | AHSP | 51327 | 20 | 10 | 66 |
Total number of gains: 95; Total number of losses: 47; Total Number of normals: 346.
Somatic mutations of AHSP:
Generating mutation plots.
Highly correlated genes for AHSP:
Showing top 20/630 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AHSP | ARHGAP1 | 0.7849 | 3 | 0 | 3 |
| AHSP | PPP1R15A | 0.772246 | 3 | 0 | 3 |
| AHSP | MUC6 | 0.758119 | 4 | 0 | 4 |
| AHSP | VAMP2 | 0.754683 | 3 | 0 | 3 |
| AHSP | SSNA1 | 0.722045 | 3 | 0 | 3 |
| AHSP | GRM8 | 0.721705 | 4 | 0 | 4 |
| AHSP | SCAF1 | 0.716965 | 3 | 0 | 3 |
| AHSP | ITGA8 | 0.711505 | 4 | 0 | 4 |
| AHSP | EPN3 | 0.704331 | 3 | 0 | 3 |
| AHSP | GRIN2D | 0.703782 | 3 | 0 | 3 |
| AHSP | LYPLA2 | 0.703728 | 4 | 0 | 3 |
| AHSP | TSC22D4 | 0.693595 | 4 | 0 | 3 |
| AHSP | RILP | 0.691586 | 3 | 0 | 3 |
| AHSP | CA5B | 0.69069 | 4 | 0 | 3 |
| AHSP | AKT1S1 | 0.687927 | 4 | 0 | 4 |
| AHSP | TP53I11 | 0.686744 | 4 | 0 | 3 |
| AHSP | LAMP1 | 0.675737 | 3 | 0 | 3 |
| AHSP | CASKIN2 | 0.675059 | 3 | 0 | 3 |
| AHSP | BTD | 0.67483 | 3 | 0 | 3 |
| AHSP | RHOT2 | 0.674441 | 3 | 0 | 3 |
For details and further investigation, click here
