RAX

 

Full name: retina and anterior neural fold homeobox Alias Symbol: RX
Type: protein-coding gene Cytoband: 18q21.32
Entrez ID: 30062 HGNC ID: HGNC:18662 Ensembl Gene: ENSG00000134438 OMIM ID: 601881
Drug and gene relationship at DGIdb

 

Expression of RAX:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RAX 30062 208242_at -0.0888 0.7835
GSE20347 RAX 30062 208242_at -0.1802 0.0264
GSE23400 RAX 30062 208242_at -0.2731 0.0000
GSE26886 RAX 30062 208242_at -0.0426 0.7240
GSE29001 RAX 30062 208242_at -0.5275 0.0009
GSE38129 RAX 30062 208242_at -0.2522 0.0009
GSE45670 RAX 30062 208242_at -0.1036 0.2674
GSE53622 RAX 30062 60421 -0.3184 0.0047
GSE53624 RAX 30062 60421 -0.2755 0.0017
GSE63941 RAX 30062 208242_at 0.3428 0.0437
GSE77861 RAX 30062 208242_at -0.0751 0.6501
GSE97050 RAX 30062 A_33_P3370944 0.2687 0.3225
TCGA RAX 30062 RNAseq 1.6577 0.2357

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RAX expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RAX:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RAX 30062 1 9 20
GSE20123 RAX 30062 1 9 20
GSE43470 RAX 30062 0 5 38
GSE46452 RAX 30062 1 26 32
GSE47630 RAX 30062 5 20 15
GSE54993 RAX 30062 10 0 60
GSE54994 RAX 30062 0 18 35
GSE60625 RAX 30062 0 4 7
GSE74703 RAX 30062 0 5 31
GSE74704 RAX 30062 1 6 13
TCGA RAX 30062 9 44 43

Total number of gains: 28; Total number of losses: 146; Total Number of normals: 314.  


 

Somatic mutations of RAX:

 

Generating mutation plots.

 

Highly correlated genes for RAX:

 

Showing top 20/894 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RAXCCDC1660.741675303
RAXPTPRS0.741145303
RAXOR2H20.739999606
RAXPHGR10.731225303
RAXRASGRF20.730231303
RAXFOLH10.718808303
RAXSCGN0.71383403
RAXMYL70.707698606
RAXMATN10.701625403
RAXSNX110.701439303
RAXZNF4910.698585303
RAXTLE60.694688404
RAXVIL10.692884303
RAXABCC60.692822303
RAXC3orf360.689634505
RAXPGC0.687754403
RAXMAGEA80.687675303
RAXOR10C10.683039303
RAXTMEM59L0.682499807
RAXSLC22A120.679434504

For details and further investigation, click here