| Full name: DnaJ heat shock protein family (Hsp40) member B5 | Alias Symbol: Hsc40 | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 25822 | HGNC ID: HGNC:14887 | Ensembl Gene: ENSG00000137094 | OMIM ID: 611328 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJB5 | 25822 | 212817_at | -0.5873 | 0.4861 | |
| GSE20347 | DNAJB5 | 25822 | 212817_at | 0.1591 | 0.4004 | |
| GSE23400 | DNAJB5 | 25822 | 212817_at | -0.1674 | 0.0666 | |
| GSE26886 | DNAJB5 | 25822 | 212817_at | 0.2874 | 0.0935 | |
| GSE29001 | DNAJB5 | 25822 | 212817_at | 0.2098 | 0.3656 | |
| GSE38129 | DNAJB5 | 25822 | 212817_at | -0.4638 | 0.1115 | |
| GSE45670 | DNAJB5 | 25822 | 212817_at | -0.5058 | 0.0120 | |
| GSE53622 | DNAJB5 | 25822 | 26377 | -0.4136 | 0.0217 | |
| GSE53624 | DNAJB5 | 25822 | 26377 | 0.1437 | 0.1996 | |
| GSE63941 | DNAJB5 | 25822 | 212817_at | -0.6769 | 0.0321 | |
| GSE77861 | DNAJB5 | 25822 | 212817_at | 0.0439 | 0.7725 | |
| GSE97050 | DNAJB5 | 25822 | A_33_P3369317 | -0.6796 | 0.2503 | |
| SRP007169 | DNAJB5 | 25822 | RNAseq | 3.0646 | 0.0000 | |
| SRP008496 | DNAJB5 | 25822 | RNAseq | 3.1916 | 0.0000 | |
| SRP064894 | DNAJB5 | 25822 | RNAseq | -0.3768 | 0.1743 | |
| SRP133303 | DNAJB5 | 25822 | RNAseq | -0.0372 | 0.9193 | |
| SRP159526 | DNAJB5 | 25822 | RNAseq | -1.0446 | 0.0341 | |
| SRP193095 | DNAJB5 | 25822 | RNAseq | 0.9592 | 0.0000 | |
| SRP219564 | DNAJB5 | 25822 | RNAseq | -0.4820 | 0.5165 | |
| TCGA | DNAJB5 | 25822 | RNAseq | -0.2080 | 0.1013 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by DNAJB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJB5 | 25822 | 3 | 13 | 14 | |
| GSE20123 | DNAJB5 | 25822 | 3 | 13 | 14 | |
| GSE43470 | DNAJB5 | 25822 | 3 | 10 | 30 | |
| GSE46452 | DNAJB5 | 25822 | 6 | 15 | 38 | |
| GSE47630 | DNAJB5 | 25822 | 1 | 20 | 19 | |
| GSE54993 | DNAJB5 | 25822 | 6 | 0 | 64 | |
| GSE54994 | DNAJB5 | 25822 | 6 | 12 | 35 | |
| GSE60625 | DNAJB5 | 25822 | 0 | 0 | 11 | |
| GSE74703 | DNAJB5 | 25822 | 2 | 7 | 27 | |
| GSE74704 | DNAJB5 | 25822 | 0 | 11 | 9 | |
| TCGA | DNAJB5 | 25822 | 16 | 44 | 36 |
Total number of gains: 46; Total number of losses: 145; Total Number of normals: 297.
Somatic mutations of DNAJB5:
Generating mutation plots.
Highly correlated genes for DNAJB5:
Showing top 20/707 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJB5 | EPHA7 | 0.757909 | 4 | 0 | 4 |
| DNAJB5 | DPH3 | 0.74666 | 3 | 0 | 3 |
| DNAJB5 | FNIP2 | 0.745135 | 4 | 0 | 4 |
| DNAJB5 | GIPC3 | 0.743303 | 4 | 0 | 4 |
| DNAJB5 | C20orf194 | 0.706949 | 3 | 0 | 3 |
| DNAJB5 | NKX6-1 | 0.697949 | 6 | 0 | 5 |
| DNAJB5 | CTNNA2 | 0.696254 | 3 | 0 | 3 |
| DNAJB5 | GSTT2 | 0.686451 | 3 | 0 | 3 |
| DNAJB5 | RBM24 | 0.684957 | 5 | 0 | 5 |
| DNAJB5 | ITGA1 | 0.683583 | 9 | 0 | 7 |
| DNAJB5 | HAND2-AS1 | 0.682731 | 5 | 0 | 5 |
| DNAJB5 | PDLIM7 | 0.681473 | 9 | 0 | 9 |
| DNAJB5 | LONRF2 | 0.681343 | 3 | 0 | 3 |
| DNAJB5 | CORO6 | 0.679362 | 3 | 0 | 3 |
| DNAJB5 | PALLD | 0.676198 | 8 | 0 | 7 |
| DNAJB5 | TGFB1I1 | 0.674009 | 11 | 0 | 10 |
| DNAJB5 | DHDH | 0.673696 | 3 | 0 | 3 |
| DNAJB5 | BCHE | 0.673627 | 6 | 0 | 5 |
| DNAJB5 | FLNC | 0.67258 | 9 | 0 | 8 |
| DNAJB5 | TMOD1 | 0.67257 | 7 | 0 | 5 |
For details and further investigation, click here
