| Full name: PDZ and LIM domain 7 | Alias Symbol: ENIGMA | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 9260 | HGNC ID: HGNC:22958 | Ensembl Gene: ENSG00000196923 | OMIM ID: 605903 |
| Drug and gene relationship at DGIdb | |||
Expression of PDLIM7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDLIM7 | 9260 | 203370_s_at | 0.0679 | 0.9554 | |
| GSE20347 | PDLIM7 | 9260 | 203370_s_at | 0.4335 | 0.0981 | |
| GSE23400 | PDLIM7 | 9260 | 203370_s_at | 0.0229 | 0.9078 | |
| GSE26886 | PDLIM7 | 9260 | 214122_at | 0.1376 | 0.3936 | |
| GSE29001 | PDLIM7 | 9260 | 203370_s_at | 0.1617 | 0.5790 | |
| GSE38129 | PDLIM7 | 9260 | 203370_s_at | 0.0367 | 0.9086 | |
| GSE45670 | PDLIM7 | 9260 | 1569150_x_at | -0.6368 | 0.0628 | |
| GSE53622 | PDLIM7 | 9260 | 141977 | 0.0687 | 0.6880 | |
| GSE53624 | PDLIM7 | 9260 | 87895 | -0.0281 | 0.7533 | |
| GSE63941 | PDLIM7 | 9260 | 214121_x_at | 0.7599 | 0.2552 | |
| GSE77861 | PDLIM7 | 9260 | 203370_s_at | 0.5950 | 0.1151 | |
| GSE97050 | PDLIM7 | 9260 | A_23_P144896 | -0.6683 | 0.1775 | |
| SRP007169 | PDLIM7 | 9260 | RNAseq | 1.6050 | 0.0005 | |
| SRP008496 | PDLIM7 | 9260 | RNAseq | 1.7819 | 0.0000 | |
| SRP064894 | PDLIM7 | 9260 | RNAseq | 0.8102 | 0.0070 | |
| SRP133303 | PDLIM7 | 9260 | RNAseq | 0.5176 | 0.1675 | |
| SRP159526 | PDLIM7 | 9260 | RNAseq | -0.2171 | 0.6672 | |
| SRP193095 | PDLIM7 | 9260 | RNAseq | 1.9621 | 0.0000 | |
| SRP219564 | PDLIM7 | 9260 | RNAseq | -0.4945 | 0.5302 | |
| TCGA | PDLIM7 | 9260 | RNAseq | 0.1056 | 0.2047 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PDLIM7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDLIM7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDLIM7 | 9260 | 2 | 13 | 15 | |
| GSE20123 | PDLIM7 | 9260 | 2 | 13 | 15 | |
| GSE43470 | PDLIM7 | 9260 | 1 | 11 | 31 | |
| GSE46452 | PDLIM7 | 9260 | 0 | 27 | 32 | |
| GSE47630 | PDLIM7 | 9260 | 1 | 20 | 19 | |
| GSE54993 | PDLIM7 | 9260 | 10 | 2 | 58 | |
| GSE54994 | PDLIM7 | 9260 | 2 | 17 | 34 | |
| GSE60625 | PDLIM7 | 9260 | 1 | 0 | 10 | |
| GSE74703 | PDLIM7 | 9260 | 1 | 7 | 28 | |
| GSE74704 | PDLIM7 | 9260 | 1 | 6 | 13 | |
| TCGA | PDLIM7 | 9260 | 8 | 34 | 54 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of PDLIM7:
Generating mutation plots.
Highly correlated genes for PDLIM7:
Showing top 20/799 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDLIM7 | FLNA | 0.778848 | 10 | 0 | 10 |
| PDLIM7 | C9orf47 | 0.775972 | 3 | 0 | 3 |
| PDLIM7 | ANKRD9 | 0.757459 | 3 | 0 | 3 |
| PDLIM7 | TTC7B | 0.74029 | 5 | 0 | 5 |
| PDLIM7 | MYADM | 0.731428 | 4 | 0 | 3 |
| PDLIM7 | ILK | 0.728466 | 9 | 0 | 9 |
| PDLIM7 | KCNIP3 | 0.726208 | 3 | 0 | 3 |
| PDLIM7 | MICAL2 | 0.722502 | 8 | 0 | 7 |
| PDLIM7 | SLC39A1 | 0.718581 | 3 | 0 | 3 |
| PDLIM7 | PIP5K1C | 0.716024 | 8 | 0 | 7 |
| PDLIM7 | SGIP1 | 0.715264 | 4 | 0 | 4 |
| PDLIM7 | KATNAL1 | 0.710042 | 5 | 0 | 5 |
| PDLIM7 | CHIC1 | 0.708592 | 3 | 0 | 3 |
| PDLIM7 | AMOTL1 | 0.707722 | 3 | 0 | 3 |
| PDLIM7 | FOXF2 | 0.706553 | 7 | 0 | 7 |
| PDLIM7 | TGFB1I1 | 0.70464 | 10 | 0 | 8 |
| PDLIM7 | CLMP | 0.70379 | 6 | 0 | 6 |
| PDLIM7 | MEIS3 | 0.70254 | 4 | 0 | 4 |
| PDLIM7 | ZYX | 0.702142 | 9 | 0 | 7 |
| PDLIM7 | CTNNA2 | 0.701721 | 3 | 0 | 3 |
For details and further investigation, click here
