| Full name: delta/notch like EGF repeat containing | Alias Symbol: UNQ26|bet | ||
| Type: protein-coding gene | Cytoband: 2q36.3 | ||
| Entrez ID: 92737 | HGNC ID: HGNC:24456 | Ensembl Gene: ENSG00000187957 | OMIM ID: 607299 |
| Drug and gene relationship at DGIdb | |||
Expression of DNER:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNER | 92737 | 226281_at | 0.4057 | 0.7396 | |
| GSE26886 | DNER | 92737 | 226281_at | 0.7454 | 0.0157 | |
| GSE45670 | DNER | 92737 | 226281_at | 0.4996 | 0.3281 | |
| GSE53622 | DNER | 92737 | 18174 | -0.0393 | 0.9158 | |
| GSE53624 | DNER | 92737 | 18174 | 0.0815 | 0.7692 | |
| GSE63941 | DNER | 92737 | 226281_at | -1.6333 | 0.1993 | |
| GSE77861 | DNER | 92737 | 226281_at | 0.8412 | 0.2319 | |
| SRP133303 | DNER | 92737 | RNAseq | 0.3379 | 0.5025 | |
| SRP159526 | DNER | 92737 | RNAseq | 1.4430 | 0.1973 | |
| TCGA | DNER | 92737 | RNAseq | -1.8982 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNER expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNER:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNER | 92737 | 1 | 12 | 17 | |
| GSE20123 | DNER | 92737 | 1 | 12 | 17 | |
| GSE43470 | DNER | 92737 | 2 | 8 | 33 | |
| GSE46452 | DNER | 92737 | 0 | 5 | 54 | |
| GSE47630 | DNER | 92737 | 4 | 5 | 31 | |
| GSE54993 | DNER | 92737 | 1 | 2 | 67 | |
| GSE54994 | DNER | 92737 | 6 | 13 | 34 | |
| GSE60625 | DNER | 92737 | 0 | 3 | 8 | |
| GSE74703 | DNER | 92737 | 2 | 7 | 27 | |
| GSE74704 | DNER | 92737 | 1 | 6 | 13 | |
| TCGA | DNER | 92737 | 14 | 27 | 55 |
Total number of gains: 32; Total number of losses: 100; Total Number of normals: 356.
Somatic mutations of DNER:
Generating mutation plots.
Highly correlated genes for DNER:
Showing top 20/98 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNER | MUCL1 | 0.697017 | 4 | 0 | 3 |
| DNER | FOXL1 | 0.685146 | 4 | 0 | 4 |
| DNER | LFNG | 0.678911 | 3 | 0 | 3 |
| DNER | TGFB2 | 0.671681 | 3 | 0 | 3 |
| DNER | ZNF511 | 0.671238 | 3 | 0 | 3 |
| DNER | BIRC2 | 0.670401 | 3 | 0 | 3 |
| DNER | SH3BP4 | 0.668403 | 4 | 0 | 4 |
| DNER | POU6F2-AS2 | 0.666879 | 3 | 0 | 3 |
| DNER | FGF20 | 0.659808 | 3 | 0 | 3 |
| DNER | FOXC2 | 0.654253 | 5 | 0 | 4 |
| DNER | KLF7 | 0.652973 | 4 | 0 | 3 |
| DNER | PMEPA1 | 0.648957 | 4 | 0 | 3 |
| DNER | IL31RA | 0.647082 | 4 | 0 | 4 |
| DNER | DCBLD2 | 0.646401 | 3 | 0 | 3 |
| DNER | PRTFDC1 | 0.641796 | 3 | 0 | 3 |
| DNER | OCIAD2 | 0.636588 | 3 | 0 | 3 |
| DNER | MYO10 | 0.635774 | 3 | 0 | 3 |
| DNER | TGFBI | 0.62809 | 4 | 0 | 4 |
| DNER | NOL9 | 0.624264 | 3 | 0 | 3 |
| DNER | SPRY4 | 0.623054 | 4 | 0 | 4 |
For details and further investigation, click here
