TGFBI

 

Full name: transforming growth factor beta induced Alias Symbol: BIGH3|CDB1|CDGG1
Type: protein-coding gene Cytoband: 5q31.1
Entrez ID: 7045 HGNC ID: HGNC:11771 Ensembl Gene: ENSG00000120708 OMIM ID: 601692
Drug and gene relationship at DGIdb

 

Expression of TGFBI:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TGFBI 7045 201506_at 1.6255 0.1765
GSE20347 TGFBI 7045 201506_at 2.6172 0.0000
GSE23400 TGFBI 7045 201506_at 2.0126 0.0000
GSE26886 TGFBI 7045 201506_at 3.4654 0.0000
GSE29001 TGFBI 7045 201506_at 2.7618 0.0000
GSE38129 TGFBI 7045 201506_at 2.1964 0.0000
GSE45670 TGFBI 7045 201506_at 1.6975 0.0062
GSE53622 TGFBI 7045 149586 1.8601 0.0000
GSE53624 TGFBI 7045 149586 2.7264 0.0000
GSE63941 TGFBI 7045 201506_at -3.5262 0.0858
GSE77861 TGFBI 7045 201506_at 2.2272 0.0016
GSE97050 TGFBI 7045 A_23_P156327 1.8766 0.0680
SRP007169 TGFBI 7045 RNAseq 4.3701 0.0000
SRP008496 TGFBI 7045 RNAseq 4.1434 0.0000
SRP064894 TGFBI 7045 RNAseq 2.9221 0.0000
SRP133303 TGFBI 7045 RNAseq 3.6515 0.0000
SRP159526 TGFBI 7045 RNAseq 2.2573 0.0000
SRP193095 TGFBI 7045 RNAseq 3.4625 0.0000
SRP219564 TGFBI 7045 RNAseq 3.1132 0.0001
TCGA TGFBI 7045 RNAseq 0.5827 0.0000

Upregulated datasets: 16; Downregulated datasets: 0.  

 

Survival by TGFBI expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TGFBI:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TGFBI 7045 3 11 16
GSE20123 TGFBI 7045 4 11 15
GSE43470 TGFBI 7045 4 5 34
GSE46452 TGFBI 7045 0 27 32
GSE47630 TGFBI 7045 0 21 19
GSE54993 TGFBI 7045 9 1 60
GSE54994 TGFBI 7045 3 13 37
GSE60625 TGFBI 7045 0 0 11
GSE74703 TGFBI 7045 3 4 29
GSE74704 TGFBI 7045 3 5 12
TCGA TGFBI 7045 4 36 56

Total number of gains: 33; Total number of losses: 134; Total Number of normals: 321.  

 

Somatic mutations of TGFBI:

 

Generating mutation plots.

 

Highly correlated genes for TGFBI:

 

Showing top 20/1741 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TGFBILOXL20.82960212012
TGFBIINHBA0.81491912012
TGFBICOL5A20.80339913012
TGFBIMFAP20.79439212011
TGFBILAMC20.79260412012
TGFBILPCAT10.78570212011
TGFBIWDR540.784727707
TGFBIHOMER30.78181711011
TGFBIMMP10.7806813012
TGFBITMEM184B0.77777811011
TGFBIFMNL20.775785808
TGFBITTYH30.774694707
TGFBISERPINH10.77261612012
TGFBIENAH0.76659312011
TGFBICOL5A10.7664413011
TGFBIAHR0.76250411011
TGFBIMYO5A0.76062612011
TGFBIFNDC3B0.7604212011
TGFBIARPC1B0.76018912011
TGFBILRP120.75937811011

For details and further investigation, click here