FGF20

 

Full name: fibroblast growth factor 20 Alias Symbol: 
Type: protein-coding gene Cytoband: 8p22
Entrez ID: 26281 HGNC ID: HGNC:3677 Ensembl Gene: ENSG00000078579 OMIM ID: 605558
Drug and gene relationship at DGIdb

 

FGF20 involved pathways:

KEGG pathway Description View
hsa04010MAPK signaling pathway
hsa04014Ras signaling pathway
hsa04015Rap1 signaling pathway
hsa04151PI3K-Akt signaling pathway
hsa05200Pathways in cancer
hsa05218Melanoma

 

Expression of FGF20:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FGF20 26281 220394_at 0.0061 0.9845
GSE20347 FGF20 26281 220394_at -0.0224 0.7162
GSE23400 FGF20 26281 220394_at -0.0714 0.0020
GSE26886 FGF20 26281 220394_at 0.1094 0.2173
GSE29001 FGF20 26281 220394_at -0.0109 0.9307
GSE38129 FGF20 26281 220394_at -0.0687 0.1414
GSE45670 FGF20 26281 220394_at 0.0261 0.7283
GSE53622 FGF20 26281 115187 -0.5761 0.0362
GSE53624 FGF20 26281 115187 -0.8870 0.0000
GSE63941 FGF20 26281 220394_at -0.2210 0.1296
GSE77861 FGF20 26281 220394_at 0.1621 0.6422
TCGA FGF20 26281 RNAseq -2.4191 0.0543

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by FGF20 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FGF20:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FGF20 26281 3 11 16
GSE20123 FGF20 26281 4 11 15
GSE43470 FGF20 26281 4 8 31
GSE46452 FGF20 26281 14 13 32
GSE47630 FGF20 26281 10 8 22
GSE54993 FGF20 26281 3 13 54
GSE54994 FGF20 26281 8 18 27
GSE60625 FGF20 26281 3 0 8
GSE74703 FGF20 26281 4 7 25
GSE74704 FGF20 26281 3 7 10
TCGA FGF20 26281 14 40 42

Total number of gains: 70; Total number of losses: 136; Total Number of normals: 282.  


 

Somatic mutations of FGF20:

 

Generating mutation plots.

 

Highly correlated genes for FGF20:

 

Showing top 20/173 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FGF20CCR90.727192303
FGF20SPO110.705171303
FGF20GPR220.704994303
FGF20ARPP210.671227303
FGF20NPPA0.669604303
FGF20KIAA00870.662628403
FGF20DNER0.659808303
FGF20C11orf160.658366303
FGF20KHDRBS20.657534303
FGF20C19orf470.655555303
FGF20ACVRL10.651716303
FGF20CCL10.649205303
FGF20GRIN2B0.648652303
FGF20LILRA30.647904303
FGF20GRM70.64133303
FGF20IL17A0.639649303
FGF20ODF3L10.639536303
FGF20SERPINA20.638827303
FGF20CALCB0.635214403
FGF20GBX10.632729303

For details and further investigation, click here