| Full name: interleukin 31 receptor A | Alias Symbol: CRL3|GLM-R|CRL|Glmr|IL-31RA | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 133396 | HGNC ID: HGNC:18969 | Ensembl Gene: ENSG00000164509 | OMIM ID: 609510 |
| Drug and gene relationship at DGIdb | |||
Expression of IL31RA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL31RA | 133396 | 243541_at | 0.5164 | 0.6051 | |
| GSE26886 | IL31RA | 133396 | 243541_at | 2.1875 | 0.0000 | |
| GSE45670 | IL31RA | 133396 | 243541_at | 1.0626 | 0.0073 | |
| GSE53622 | IL31RA | 133396 | 30497 | 1.3426 | 0.0000 | |
| GSE53624 | IL31RA | 133396 | 30497 | 1.5574 | 0.0000 | |
| GSE63941 | IL31RA | 133396 | 243541_at | 0.0158 | 0.9767 | |
| GSE77861 | IL31RA | 133396 | 243541_at | 0.4411 | 0.0554 | |
| SRP133303 | IL31RA | 133396 | RNAseq | 3.0137 | 0.0000 | |
| TCGA | IL31RA | 133396 | RNAseq | 1.7234 | 0.0007 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by IL31RA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL31RA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL31RA | 133396 | 0 | 13 | 17 | |
| GSE20123 | IL31RA | 133396 | 0 | 13 | 17 | |
| GSE43470 | IL31RA | 133396 | 1 | 12 | 30 | |
| GSE46452 | IL31RA | 133396 | 1 | 27 | 31 | |
| GSE47630 | IL31RA | 133396 | 2 | 16 | 22 | |
| GSE54993 | IL31RA | 133396 | 8 | 1 | 61 | |
| GSE54994 | IL31RA | 133396 | 3 | 19 | 31 | |
| GSE60625 | IL31RA | 133396 | 0 | 0 | 11 | |
| GSE74703 | IL31RA | 133396 | 1 | 9 | 26 | |
| GSE74704 | IL31RA | 133396 | 0 | 6 | 14 | |
| TCGA | IL31RA | 133396 | 7 | 46 | 43 |
Total number of gains: 23; Total number of losses: 162; Total Number of normals: 303.
Somatic mutations of IL31RA:
Generating mutation plots.
Highly correlated genes for IL31RA:
Showing top 20/611 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL31RA | SLCO1B3 | 0.778163 | 4 | 0 | 4 |
| IL31RA | AMDHD1 | 0.772757 | 3 | 0 | 3 |
| IL31RA | B4GALNT1 | 0.74868 | 3 | 0 | 3 |
| IL31RA | TGIF1 | 0.737978 | 4 | 0 | 4 |
| IL31RA | C14orf119 | 0.725042 | 3 | 0 | 3 |
| IL31RA | CD276 | 0.716775 | 3 | 0 | 3 |
| IL31RA | TBCE | 0.702311 | 4 | 0 | 4 |
| IL31RA | LAMA5 | 0.701107 | 3 | 0 | 3 |
| IL31RA | CPT1A | 0.694877 | 3 | 0 | 3 |
| IL31RA | TGFBI | 0.691293 | 6 | 0 | 6 |
| IL31RA | MFAP2 | 0.689336 | 5 | 0 | 5 |
| IL31RA | TRAM2 | 0.684682 | 5 | 0 | 5 |
| IL31RA | SLC52A1 | 0.681614 | 3 | 0 | 3 |
| IL31RA | ACVR1 | 0.678924 | 6 | 0 | 6 |
| IL31RA | SNAI2 | 0.677251 | 4 | 0 | 4 |
| IL31RA | COPS8 | 0.675887 | 4 | 0 | 3 |
| IL31RA | ITGA3 | 0.675311 | 6 | 0 | 6 |
| IL31RA | NPW | 0.671981 | 3 | 0 | 3 |
| IL31RA | TENM2 | 0.667613 | 6 | 0 | 6 |
| IL31RA | PLOD1 | 0.666905 | 5 | 0 | 5 |
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