| Full name: transmembrane channel like 7 | Alias Symbol: FLJ21240 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 79905 | HGNC ID: HGNC:23000 | Ensembl Gene: ENSG00000170537 | OMIM ID: 617198 |
| Drug and gene relationship at DGIdb | |||
Expression of TMC7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMC7 | 79905 | 220021_at | 0.3450 | 0.1782 | |
| GSE20347 | TMC7 | 79905 | 220021_at | 0.1636 | 0.0035 | |
| GSE23400 | TMC7 | 79905 | 220021_at | -0.0024 | 0.9214 | |
| GSE26886 | TMC7 | 79905 | 220021_at | 0.3578 | 0.0550 | |
| GSE29001 | TMC7 | 79905 | 220021_at | 0.0853 | 0.5949 | |
| GSE38129 | TMC7 | 79905 | 220021_at | 0.1307 | 0.0643 | |
| GSE45670 | TMC7 | 79905 | 220021_at | 0.3939 | 0.0319 | |
| GSE53622 | TMC7 | 79905 | 112558 | 0.8607 | 0.0000 | |
| GSE53624 | TMC7 | 79905 | 112558 | 1.1597 | 0.0000 | |
| GSE63941 | TMC7 | 79905 | 220021_at | 0.3532 | 0.1944 | |
| GSE77861 | TMC7 | 79905 | 220021_at | 0.0800 | 0.5078 | |
| GSE97050 | TMC7 | 79905 | A_23_P140928 | 0.4210 | 0.1791 | |
| SRP007169 | TMC7 | 79905 | RNAseq | 3.1281 | 0.0001 | |
| SRP008496 | TMC7 | 79905 | RNAseq | 4.0849 | 0.0000 | |
| SRP064894 | TMC7 | 79905 | RNAseq | 1.1702 | 0.0000 | |
| SRP133303 | TMC7 | 79905 | RNAseq | 0.6483 | 0.0000 | |
| SRP159526 | TMC7 | 79905 | RNAseq | 1.1928 | 0.0000 | |
| SRP193095 | TMC7 | 79905 | RNAseq | 0.5448 | 0.0170 | |
| SRP219564 | TMC7 | 79905 | RNAseq | 0.6289 | 0.1087 | |
| TCGA | TMC7 | 79905 | RNAseq | 0.3659 | 0.0173 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by TMC7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMC7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMC7 | 79905 | 5 | 3 | 22 | |
| GSE20123 | TMC7 | 79905 | 5 | 2 | 23 | |
| GSE43470 | TMC7 | 79905 | 3 | 3 | 37 | |
| GSE46452 | TMC7 | 79905 | 38 | 1 | 20 | |
| GSE47630 | TMC7 | 79905 | 11 | 6 | 23 | |
| GSE54993 | TMC7 | 79905 | 3 | 5 | 62 | |
| GSE54994 | TMC7 | 79905 | 3 | 10 | 40 | |
| GSE60625 | TMC7 | 79905 | 4 | 0 | 7 | |
| GSE74703 | TMC7 | 79905 | 3 | 2 | 31 | |
| GSE74704 | TMC7 | 79905 | 2 | 1 | 17 | |
| TCGA | TMC7 | 79905 | 20 | 12 | 64 |
Total number of gains: 97; Total number of losses: 45; Total Number of normals: 346.
Somatic mutations of TMC7:
Generating mutation plots.
Highly correlated genes for TMC7:
Showing top 20/873 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMC7 | FAM161A | 0.829164 | 3 | 0 | 3 |
| TMC7 | PAPOLG | 0.797217 | 3 | 0 | 3 |
| TMC7 | CENPBD1 | 0.774533 | 3 | 0 | 3 |
| TMC7 | GNS | 0.773511 | 3 | 0 | 3 |
| TMC7 | ZNF789 | 0.757152 | 3 | 0 | 3 |
| TMC7 | CPT1C | 0.740217 | 4 | 0 | 4 |
| TMC7 | MAPKAPK5 | 0.737098 | 4 | 0 | 4 |
| TMC7 | DOCK7 | 0.733191 | 3 | 0 | 3 |
| TMC7 | MOB3C | 0.725347 | 3 | 0 | 3 |
| TMC7 | ZDHHC16 | 0.722241 | 5 | 0 | 4 |
| TMC7 | SLC7A6OS | 0.721909 | 3 | 0 | 3 |
| TMC7 | RFNG | 0.718651 | 3 | 0 | 3 |
| TMC7 | ZFP69B | 0.714685 | 3 | 0 | 3 |
| TMC7 | PHRF1 | 0.713232 | 3 | 0 | 3 |
| TMC7 | TAF1C | 0.712472 | 3 | 0 | 3 |
| TMC7 | RCBTB1 | 0.709047 | 3 | 0 | 3 |
| TMC7 | CLEC12A | 0.708801 | 3 | 0 | 3 |
| TMC7 | RNF220 | 0.706191 | 3 | 0 | 3 |
| TMC7 | PTCD3 | 0.706064 | 3 | 0 | 3 |
| TMC7 | KLHL8 | 0.705645 | 3 | 0 | 3 |
For details and further investigation, click here
